HSV-1 virulence for mice by the intracerebral route is encoded by the BamHI-L DNA fragment containing the cell fusion gene

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

An Improved Technique for Obtaining Enhanced Infectivity with Herpes Simplex Virus Type 1 DNA

1976 • 304 citations

Molecular Genetics of Herpes Simplex Virus II. Mapping of the Major Viral Glycoproteins and of the Genetic Loci Specifying the Social Behavior of Infected Cells

1979 • 303 citations

Comparative Neurovirulence of Herpes Simplex Virus Type 1 Strains After Peripheral or Intracerebral Inoculation of BALB/c Mice

1983 • 226 citations

Ocular disease pattern induced by herpes simplex virus is genetically determined by a specific region of viral DNA.

1982 • 131 citations

Physical location of a herpes simplex virus type-1 gene function(s) specifically associated with a 10 million-fold increase in HSV neurovirulence

1983 • 128 citations

Nucleotide sequence of a herpes simplex virus type 1 gene that causes cell fusion

1985 • 125 citations

Functional and molecular analyses of the avirulent wild-type herpes simplex virus type 1 strain KOS

1986 • 100 citations

Expression of the syncytial (syn) phenotype in HSV-1, strain KOS: Genetic and phenotypic studies of mutants in two syn loci

1981 • 74 citations

A sequence in HpaI-P fragment of herpes simplex virus-1 DNA determines intraperitoneal virulence in mice

1986 • 63 citations

Rescue of a herpes simplex virus type 1 neurovirulence function with a cloned DNA fragment

1985 • 61 citations

Transduction of virulence in herpes simplex virus type 1 from a pathogenic to an apathogenic strain by a cloned viral DMA fragment

1985 • 50 citations

Replacement of the deletion in the genome (0.762–0.789 mu) of avirulent HSV-1 HFEM using cloned Mlul DNA fragment (0.7615–0.796 mu) of virulent HSV-1 F leads to generation of virulent intratypic recombinant

1986 • 43 citations

Mapping of the deletion in the genome of HSV-1 strain HFEM responsible for its avirulent phenotype

1985 • 36 citations

Herpes simplex virus type 1 DNA sequences which direct spread of virus from comes to central nervous system

1986 • 32 citations

In vitro cytopathology and pathogenicity to inbred mice shown by five variants of a laboratory strain of type 1 herpes simplex virus

1986 • 15 citations