Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA.
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Abstract
References (17)
Characterization of Herpes Simplex Virus Strains Differing in their Effects on Social Behaviour of Infected Cells
1968 • 874 citations
The superfamily of arginine/serine-rich splicing factors.
1995 • 671 citations
Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors
1994 • 612 citations
Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators
1991 • 508 citations
The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.
1984 • 371 citations
An Inquiry into the Mechanisms of Herpes Simplex Virus Latency
1987 • 323 citations
Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA
1996 • 258 citations
Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies
1984 • 184 citations
Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways.
1995 • 174 citations
Herpes simplex genes: the blueprint of a succesful human pathogen
1994 • 122 citations
Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript
1994 • 93 citations
The promoter and transcriptional unit of a novel herpes simplex virus 1 alpha gene are contained in, and encode a protein in frame with, the open reading frame of the alpha 22 gene
1996 • 81 citations
The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genome
1995 • 63 citations
SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element
1996 • 62 citations
Cloning and expression of a cDNA covering the complete coding region of the P32 subunit of human pre-m RNA splicing factor SF2
1993 • 60 citations
Application of antibody to synthetic peptides for characterization of the intact and truncated alpha 22 protein specified by herpes simplex virus 1 and the R325 alpha 22- deletion mutant
1985 • 52 citations
Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene
1996 • 37 citations