Spatiotemporal responses of astrocytes, ramified microglia, and brain macrophages to central neuronal infection with pseudorabies virus

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

Cytology & cellular pathology of the nervous system

1965 • 1,037 citations

Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

1982 • 1,021 citations

Functional plasticity of microglia: A review

1988 • 931 citations

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

1985 • 881 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Cellular immune reactivity within the CNS

1986 • 771 citations

Mapping of Herpes Simplex Virus-1 Neurovirulence to γ ₁ 34.5, a Gene Nonessential for Growth in Culture

1990 • 705 citations

Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization

1988 • 587 citations

A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections

1989 • 574 citations

The central organization of the vagus nerve innervating the stomach of the rat

1985 • 490 citations

CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labelling with pseudorabies virus

1989 • 484 citations

Amygdaloid and basal forebrain direct connections with the nucleus of the solitary tract and the dorsal motor nucleus

1982 • 432 citations

Immunoregulators in the nervous system

1991 • 380 citations

Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

1988 • 368 citations

Neurotropic properties of pseudorabies virus: uptake and transneuronal passage in the rat central nervous system

1990 • 337 citations

Astrocytes increase in glial fibrillary acidic protein during retrograde changes of facial motor neurons

1986 • 255 citations

Viral particles induce Ia antigen expression on astrocytes

1986 • 241 citations

Viruses as transneuronal tracers

1990 • 236 citations

Direction of transneuronal transport of herpes simplex virus 1 in the primate motor system is strain-dependent.

1991 • 221 citations

Glial changes following an excitotoxic lesion in the CNS—I. Microglia/macrophages

1991 • 215 citations

New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury

1990 • 213 citations

Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system

1992 • 212 citations

Retrograde transneuronal transfer of Herpes simplex virus type 1 (HSV 1) from motoneurones

1987 • 195 citations

Effect of cloned interferon‐γ on expression of H‐2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin

1984 • 192 citations

Effect of brefeldin A on alphaherpesvirus membrane protein glycosylation and virus egress

1991 • 183 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

Transneuronal Transfer of Herpes Virus from Peripheral Nerves to Cortex and Brainstem

1989 • 175 citations

Transneuronal labeling of spinal interneurons and sympathetic preganglionic neurons after pseudorabies virus injections in the rat medial gastrocnemius muscle

1992 • 143 citations

Molecular Biology of Pseudorabies Virus

1985 • 141 citations

Neuron to neuron transmission of herpes simplex virus

1982 • 136 citations

VIRUSES AND THE VERSATILE MACROPHAGE

1985 • 136 citations

Neuronal and transneuronal tracing in the trigeminal system of the rat using the herpes virus suis

1983 • 134 citations

Aujeszky’s Disease (Pseudorabies) in Pigs

1989 • 129 citations

Neural spread of herpes simplex virus types 1 and 2 in mice after corneal or subcutaneous (footpad) inoculation

1978 • 127 citations

An investigation into the early stages of the inflammatory response following ibotenic acid-induced neuronal degeneration

1990 • 115 citations

Study on the propagation of Herpes simplex virus (type 2) into the brain after intraocular injection

1974 • 111 citations

Mechanisms of antiviral immunity induced by a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: cytotoxic T cells

1987 • 108 citations

Human cytotoxic T cell clones directed against herpes simplex virus-infected cells. IV. Recognition and activation by cloned glycoproteins gB and gD.

1986 • 101 citations

Macrophages in the central nervous system of the rat

1987 • 100 citations

Differences in attachment between herpes simplex type 1 and type 2 viruses to neurons and glial cells

1980 • 97 citations

Modification of astrocytes in the spinal cord following dorsal root or peripheral nerve lesions

1990 • 90 citations

Attachment of Herpes Simplex Virus to Neurons and Glial Cells

1978 • 86 citations

Intraaxonal transport of Herpes simplex virus in the rat central nervous system

1977 • 86 citations

Microglial mitogens are produced in the developing and injured mammalian brain.

1991 • 85 citations

Identification of herpes simplex virus type 1 (HSV-1) glycoprotein gC as the immunodominant antigen for HSV-1-specific memory cytotoxic T lymphocytes.

1985 • 82 citations

Golgi-like, transneuronal retrograde labelling with CNS injections of herpes simplex virus type

1989 • 80 citations

The Pathogenesis of Pseudorabies in Mice following Peripheral Inoculation

1974 • 79 citations

Herpes simplex virus type I infection of the CNS induces major histocompatibility complex antigen expression on rat microglia

1990 • 79 citations

Abortive and productive infections of human mononuclear phagocytes by type I herpes simplex virus.

1978 • 79 citations

Herpes simplex virus type 1-specific cytotoxic T lymphocytes recognize virus nonstructural proteins

1988 • 78 citations

Persistence of fluoro-gold following degeneration of labeled motoneurons is due to phagocytosis by microglia and macrophages

1991 • 77 citations

Transneuronal transport of herpes simplex virus from the cervical vagus to brain neurons with axonal inputs to central vagal sensory nuclei in the rat

1991 • 74 citations

Somatostatinergic projections from the central nucleus of the amygdala to the vagal nuclei

1983 • 73 citations

Projections from rabbit caudal medulla to C1 and A5 sympathetic premotor neurons, demonstrated with phaseolus leucoagglutinin and herpes simplex virus

1992 • 66 citations

The gene encoding the gIII envelope protein of pseudorabies virus vaccine strain Bartha contains a mutation affecting protein localization

1989 • 62 citations

Neuronal organization of the stapedius reflex pathways in the rat: a retrograde HRP and viral transneuronal tracing study

1989 • 52 citations

Selective spread of herpes simplex virus in the central nervous system after ocular inoculation

1989 • 51 citations

Herpes simplex virus (HSV)-specific proliferative and cytotoxic T-cell responses in humans immunized with an HSV type 2 glycoprotein subunit vaccine

1988 • 41 citations

Interactions of Pseudorabies virus with swine alveolar macrophages I: virus replication

1989 • 41 citations

Intrinsic resistance to viral infection. Mouse macrophage restriction of herpes simplex virus replication.

1988 • 39 citations

Herpes simplex virus glycoprotein D is recognized as antigen by CD4+ and CD8+ T lymphocytes from infected mice. Characterization of T cell clones.

1990 • 39 citations

Tensor tympani reflex pathways studied with retrograde horseradish peroxidase and transneuronal viral tracing techniques

1986 • 39 citations

Evaluation of Antiviral Immunity Using Vaccinia Virus Recombinants Expressing Cloned Genes for Herpes Simplex Virus Type 1 Glycoproteins

1989 • 37 citations

Retrograde transneuronal transport of Herpex simplex virus in the retina after injection in the superior colliculus, hypothalamus and optic chiasm

1989 • 36 citations

Herpes simplex virus, type 1 invasion of the rabbit and mouse nervous systems revealed by in situ hybridization

1987 • 26 citations

The morphology of somatostatin-immunoreactive neurons in the lateral nucleus of the rat amygdala

1983 • 24 citations

Spread of herpes simplex virus type 1 in the central nervous system during experimentally reactivated encephalitis

1990 • 24 citations

Innate resistance to herpes simplex virus infection. Human lymphocyte and monocyte inhibition of viral replication.

1990 • 22 citations

Identifying HSV infected neurons after ocular inoculation

1987 • 22 citations

Infiltration of carbon-labelled monocytes into the dorsal motor nucleus following an intraneural injection of ricinus communis agglutinin-60 into the vagus nerve in rats.

1988 • 21 citations

Variation in resistance to herpes simplex virus type 1 of oligodendrocytes derived from inbred strains of mice

1991 • 18 citations

The different interactions of a gIII mutant of pseudorabies virus with several different cell types

1992 • 14 citations

Herpes simplex virus: neuroinvasiveness, neurovirulence and latency

1991 • 12 citations

Viruses, the immune system and central nervous system diseases

1988 • 7 citations