Phosphorylation and Sequestration of Serotonin Transporters Differentially Modulated by Psychostimulants

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

Structure and function of the brain serotonin system

1992 • 2,507 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Pharmacological profile of antidepressants and related compounds at human monoamine transporters

1997 • 906 citations

Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter

1994 • 904 citations

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 • 883 citations

Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity

1999 • 873 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

Altered Brain Serotonin Homeostasis and Locomotor Insensitivity to 3,4-Methylenedioxymethamphetamine (“Ecstasy”) in Serotonin Transporter-Deficient Mice

1998 • 704 citations

Mechanisms of Amphetamine Action Revealed in Mice Lacking the Dopamine Transporter

1998 • 622 citations

Cloning of a Serotonin Transporter Affected by Antidepressants

1991 • 613 citations

Primary Structure of the Human Platelet Serotonin Uptake Site: Identity with the Brain Serotonin Transporter

1993 • 543 citations

Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake

1984 • 528 citations

The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release.

1992 • 526 citations

Cocaine self-administration in dopamine-transporter knockout mice

1998 • 523 citations

Cocaine reward models: Conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice

1998 • 502 citations

Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides

1982 • 478 citations

Mechanism of Transport and Storage of Neurotransmitter

1987 • 471 citations

Evidence of linkage between the serotonin transporter and autistic disorder

1997 • 435 citations

Molecular Physiology of Norepinephrine and Serotonin Transporters

1994 • 404 citations

Cocaine, Ethanol, and Genotype Effects on Human Midbrain Serotonin Transporter Binding Sites and mRNA Levels

1998 • 390 citations

Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression

1997 • 377 citations

Phosphorylation and Regulation of Antidepressant-sensitive Serotonin Transporters

1998 • 312 citations

Protein Kinase C-mediated Phosphorylation and Functional Regulation of Dopamine Transporters in Striatal Synaptosomes

1997 • 298 citations

Amphetamine and Other Weak Bases Act to Promote Reverse Transport of Dopamine in Ventral Midbrain Neurons

1993 • 290 citations

Conducting states of a mammalian serotonin transporter

1994 • 286 citations

Uptake inhibitors increase extracellular serotonin concentration measured by brain microdialysis

1994 • 261 citations

Neurotransmitter transporters : structure, function, and regulation

2002 • 251 citations

Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders

1998 • 248 citations

Role of Serotonin in Depression^a

1990 • 239 citations

Serotonin Uptake in Blood Platelets of Psychiatric Patients

1981 • 235 citations

Addiction to Cocaine and Amphetamine

1996 • 234 citations

The peripheral actions of 5-Hydroxytryptamine

1990 • 234 citations

Biology of serotonergic transmission

1983 • 214 citations

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

1994 • 211 citations

The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

1992 • 209 citations

The Third Transmembrane Domain of the Serotonin Transporter Contains Residues Associated with Substrate and Cocaine Binding

1997 • 208 citations

Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP.

1994 • 194 citations

How Common Is Resistance to Treatment in Recurrent, Nonpsychotic Geriatric Depression?

1998 • 187 citations

Phorbol Esters Increase Dopamine Transporter Phosphorylation and Decrease Transport V_max

1997 • 187 citations

Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes.

1997 • 186 citations

Repeated Cocaine Modifies the Mechanism by which Amphetamine Releases Dopamine

1997 • 178 citations

Serotonin Uptake and Serotonin Uptake Inhibition

1990 • 176 citations

Carrier‐dependent and Ca²⁺‐dependent 5‐HT and dopamine release induced by (+)‐amphetamine, 3,4‐methylendioxy‐methamphetamine, p‐chloroamphetamine and (+)‐fenfluramine

1997 • 175 citations

Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 173 citations

Regulation of γ-Aminobutyric Acid (GABA) Transporters by Extracellular GABA

1999 • 164 citations

Regulation of the functional activity of the human dopamine transporter by protein kinase C

1997 • 161 citations

SEROTONERGIC MODULATION OF BEHAVIOUR: A PHYLOGENETIC OVERVIEW

1997 • 156 citations

Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter

1998 • 148 citations

Protein Kinase C Regulates the Interaction between a GABA Transporter and Syntaxin 1A

1998 • 136 citations

Listening to Neurotransmitter Transporters

1996 • 120 citations

Phorbol esters alter functions of the expressed dopamine transporter

1994 • 118 citations

Activators of protein kinase C decrease serotonin transport in human platelets

1992 • 102 citations

Marked Reduction in the Number of Platelet—Tritiated Imipramine Binding Sites in Geriatric Depression

1988 • 100 citations

Protein kinase C activators decrease dopamine uptake into striatal synaptosomes.

1996 • 99 citations

Modulation of Serotonin Transporter Activity by a Protein Kinase C Activator and an Inhibitor of Type 1 and 2A Serine/Threonine Phosphatases

1997 • 90 citations

Pore models for transporters?

1996 • 78 citations

Role of Protein Kinase C and Second Messengers in Regulation of the Norepinephrine Transporter

1997 • 65 citations

Blocking Action of Sympathomimetic Amines on the Uptake of Tritiated Noradrenaline by Mouse Cerebral Cortex Tissues In Vitro.

1964 • 65 citations

Inhibition of high-affinity gamma-aminobutyric acid uptake in primary astrocyte cultures by phorbol esters and phospholipase C

1991 • 61 citations

Regulation of Antidepressant-Sensitive Serotonin Transporters

1997 • 53 citations

Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens:

1997 • 47 citations

Mechanisms of Biogenic Amine Neurotransmitter Transporters

1997 • 43 citations

[16] Ion-coupled neurotransmitter transport: Thermodynamic vs. kinetic determinations of stoichiometry

1998 • 40 citations

Production, Purification, and Characterization of Recombinant 2′,5′-Oligoadenylate Synthetases

1998 • 39 citations

[24] Biosynthesis, N-glycosylation, and surface trafficking of biogenic amine transporter proteins

1998 • 34 citations

Possible involvement of calmodulin-dependent kinases in Ca2+-dependent enhancement of [3H]5-hydroxytryptamine uptake in rat cortex

1996 • 31 citations

The substrates of a sodium- and chloride-coupled .gamma.-aminobutyric acid transporter protect multiple sites throughout the protein against proteolytic cleavage

1993 • 26 citations

Role of calcium ion in platelet serotonin uptake regulation

1995 • 21 citations

Drug inhibition indicates a single-site model of the 5-HT uptake site/antidepressant binding site in rat and human brain

1989 • 21 citations

Carrier-mediated Serotonin Release Induced by d-Fenfluramine: Studies with Human Neuroblastoma Cells Transfected with a Rat Serotonin Transporter

1997 • 14 citations

Selective effect of phorbol ester on serotonin removal and ACE activity in rabbit lungs

1988 • 13 citations