Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

Précis ofThe neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system

1982 • 4,511 citations

A Systematic Method for Clinical Description and Classification of Personality Variants

1987 • 3,661 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

Psychopharmacology: The Fourth Generation of Progress

1995 • 2,920 citations

Allelic Variation of Human Serotonin Transporter Gene Expression

1996 • 2,225 citations

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1992 • 1,956 citations

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking

1996 • 1,498 citations

Personality in adulthood

1990 • 1,339 citations

Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking

1996 • 1,207 citations

Current advances and trends in the treatment of depression

1994 • 1,111 citations

A unified biosocial theory of personality and its role in the development of anxiety states.

1986 • 1,090 citations

The Genetic Basis of Complex Human Behaviors

1994 • 1,028 citations

Description and Measurement of Personality.

1947 • 980 citations

The description of personality: basic traits resolved into clusters.

1943 • 972 citations

Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter

1994 • 904 citations

Mendelian factors underlying quantitative traits in tomato: comparison across species, generations, and environments.

1991 • 900 citations

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 • 883 citations

Differential Diagnosis of Personality Disorders by the Seven-Factor Model of Temperament and Character

1993 • 786 citations

Psychopharmacology: The Fourth Generation of Progress

1996 • 755 citations

Personality in adulthood

1991 • 687 citations

Organization of the human serotonin transporter gene

1994 • 623 citations

HANDBOOK OF ABNORMAL PSYCHOLOGY

1961 • 561 citations

Polymorphism in serotonin transporter gene associated with susceptibility to major depression

1996 • 534 citations

5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research

1995 • 497 citations

Symptoms of Anxiety and Symptoms of Depression

1987 • 448 citations

A Simple Genetic Basis for a Complex Psychological Trait in Laboratory Mice

1995 • 447 citations

Personality: Structure and Assessment

1992 • 388 citations

Testing a model for the genetic structure of personality: A comparison of the personality systems of Cloninger and Eysenck.

1994 • 378 citations

The Lifetime History of Major Depression in Women

1993 • 325 citations

Testing a model for the genetic structure of personality: A comparison of the personality systems of Cloninger and Eysenck.

1994 • 301 citations

Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene

1995 • 294 citations

Linkage between sexual orientation and chromosome Xq28 in males but not in females

1995 • 276 citations

5-Hydroxytryptamine pathways in anxiety and its treatment

1995 • 247 citations

The genetics of six neurotic disorders: a twin study

1990 • 246 citations

Neuroticism, extraversion, and related traits in adult twins reared apart and reared together.

1988 • 233 citations

Isolation of a cDNA encoding the human brain serotonin transporter

1993 • 223 citations

Neuroticism, extraversion, and related traits in adult twins reared apart and reared together.

1988 • 218 citations

Handbook of Abnormal Psychology

1961 • 198 citations

The serotonin transporter is a potential susceptibility factor for bipolar affective disorder

1996 • 193 citations

Serotonin as a regulator of craniofacial morphogenesis: Site specific malformations following exposure to serotonin uptake inhibitors

1992 • 166 citations

Serotonin; From cell biology to pharmacology and therapeutics

1991 • 153 citations

Partitioning environmental and genetic contributions to behavioral development.

1989 • 150 citations

Chronic antidepressant treatment and central 5-HT synapses

1983 • 142 citations

Serotonin Upregulates Mitogen-Stimulated B Lymphocyte Proliferation through 5-HT1AReceptors

1995 • 140 citations

Testing the association between polymorphic markers and quantitative traits in pedigrees

1987 • 139 citations

Primary structure of the serotonin transporter in unipolar depression and bipolar disorder

1995 • 121 citations

Expression of a high-affinity serotonin transporter in human lymphocytes

1994 • 114 citations

A unified biosocial theory of personality and its role in the development of anxiety states: a reply to commentaries.

1988 • 108 citations

Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus

1994 • 102 citations

Temperament and early environment influence comorbidity and personality disorders in major depression

1994 • 102 citations

Fluoxetine: a review of receptor and functional effects and their clinical implications

1992 • 101 citations

Linkage mapping of serotonin transporter protein gene SLC6A4 on chromosome 17

1995 • 97 citations

Gene Polymorphism but not Catalytic Activity of Angiotensin I–Converting Enzyme Is Associated With Coronary Artery Disease and Myocardial Infarction in Low-Risk Patients

1995 • 95 citations

Studies of a neurochemical link between depression, anxiety, and stress from [3H]imipramine and [3H]paroxetine binding on human platelets

1994 • 95 citations

Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction.

1995 • 92 citations

Association analyses of the polymorphisms of angiotensin-converting enzyme and angiotensinogen genes with diabetic nephropathy in Japanese non-insulin-dependent diabetics

1996 • 89 citations

Handbook of Depression and Anxiety

1995 • 80 citations

Effects of sertraline and citalopram given repeatedly on the responsiveness of 5-HT receptor subpopulations

1992 • 72 citations

Advances in the neurobiology of anxiety disorders

1996 • 64 citations

Intact coding region of the serotonin transporter gene in obsessive-compulsive disorder

1996 • 58 citations

Cyclic AMP-independent Up-regulation of the Human Serotonin Transporter by Staurosporine in Choriocarcinoma Cells

1995 • 55 citations

Genotype€nvironment interaction in personality development: Indentical twins reared apart.

1988 • 54 citations

The angiotensin‐converting enzyme (ACE) genetic polymorphism: its relationship with plasma ACE level and myocardial infarction

1994 • 52 citations

Quantitative autoradiography of 3H-paroxetine binding sites in rat brain

1992 • 45 citations

Genotype€nvironment interaction in personality development: Indentical twins reared apart.

1988 • 33 citations

Comparative study of platelet 3H-paroxetine and 3H-imipramine binding in panic disorder patients and healthy controls.

1994 • 32 citations

Fluoxetine effects on cerebral glucose metabolism

1994 • 29 citations

A pharmacological comparison of citalopram, a bicyclic serotonin selective uptake inhibitor, with traditional tricyclic antidepressants

1993 • 28 citations

Biological dissection of anxiety disorders

1995 • 26 citations

Serotonin dysfunction syndromes

1993 • 23 citations

Lack of association between three genetic markers of brain growth factors and infantile autism

1994 • 9 citations

In vitro effects of prealbumin on T-cell-dependent immune responses of the mouse

1981 • 6 citations

Statistical validity for testing associations between genetic markers and quantitative traits in family data

1995 • 6 citations

Anxiolytic Effects of Drugs Acting on 5-HT Receptor Subtypes

1993 • 4 citations

NEWS Doubt about national ageing research centre for UK

1996 • 1 citations

Clinical Lecture ON WHOOPING- COUGH.

1876 • 1 citations