The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release.

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity

1988 • 548 citations

Isolation and Characterization of Plasma Membranes from Human Blood Platelets

1970 • 429 citations

Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals

1985 • 371 citations

Effects of enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices

1986 • 312 citations

In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain

1987 • 301 citations

Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites

1988 • 299 citations

Active transport of 5-hydroxytryptamine by plasma membrane vesicles isolated from human blood platelets.

1977 • 224 citations

Bioenergetics of secretory vesicles

1986 • 211 citations

Evidence for dual serotonergic projections to neocortex: Axons from the dorsal and median raphe nuclei are differentially vulnerable to the neurotoxin p-chloroamphetamine (PCA)

1988 • 183 citations

Effects of certain hallucinogenic amphetamine analogs on the release of [3H]-serotonin from rat brain synaptosomes

1982 • 180 citations

Coupling between platelet 5-hydroxytryptamine and potassium transport.

1979 • 160 citations

Mechanism of imipramine inhibition of platelet 5-hydroxytryptamine transport.

1979 • 139 citations

Lowering of brain serotonin level by chloramphetamines

1965 • 123 citations

Anatomic evidence for a neurotoxic effect of (±)-fenfluramine upon serotonergic projections in the rat

1990 • 121 citations

Coupling of transmembrane proton gradients to platelet serotonin transport.

1982 • 119 citations

Reversible and irreversible phases of serotonin depletion by 4-chloroamphetamine

1975 • 109 citations

Platelet 5-hydroxytryptamine transport, an electroneutral mechanism coupled to potassium

1978 • 108 citations

Role of a transmembrane pH gradient in epinephrine transport by chromaffin granule membrane vesicles.

1978 • 102 citations

The importance of neuronal uptake of amines for amphetamine-induced release of 3H-norepinephrine from isolated brain tissue.

1974 • 102 citations

The serotonin transporter-imipramine "receptor".

1983 • 94 citations

The role of chloride ion in platelet serotonin transport.

1982 • 90 citations

Stoichiometry of hydrogen ion-linked dopamine transport in chromaffin granule ghosts

1981 • 81 citations

Single-site model of the neuronal 5-hydroxytryptamine uptake and imipramine-binding site.

1986 • 80 citations

Intracellular Distribution of Histamine

1954 • 74 citations

Evidence for two distinct serotonin transport systems in platelets.

1980 • 72 citations

The transport of (+)-amphetamine by the neuronal noradrenaline carrier

1984 • 70 citations

Bioenergetics of serotonin transport by membrane vesicles derived from platelet dense granules.

1982 • 64 citations

Decrease of cerebral 5-hydroxytryptamine and 5-hydroxyindolacetic acid by an arylalkylamine

1963 • 58 citations

Hallucinogens, neurochemical, behavioral, and clinical perspectives

1984 • 58 citations

Fenfluramine: Long-term reduction in brain serotonin (5-hydroxytryptamine)

1976 • 55 citations

The role of a transmembrane pH gradient in 5‐hydroxy tryptamine uptake by synaptic vesicles from rat brain

1979 • 49 citations

Functional asymmetry of the amine transporter from chromaffin granules.

1983 • 48 citations

Mechanism by which uptake inhibitors antagonizep-chloroamphetamine-induced depletion of brain serotonin

1980 • 42 citations

Two types of 5-hydroxytryptamine release from isolated blood platelets

1964 • 38 citations

Antidepressant binding to the porcine and human platelet serotonin transporters.

1988 • 35 citations

QuaSAR : quantitative structure activity relationships of analgesics, narcotic antagonists, and hallucinogens

1978 • 28 citations

Kinetics of tyramine transport and permeation across chromaffin-vesicle membranes

1984 • 25 citations

Characterization of native and reconstituted hydrogen ion-pumping adenosine triphosphatase of chromaffin granules

1986 • 17 citations

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