SEROTONERGIC MODULATION OF BEHAVIOUR: A PHYLOGENETIC OVERVIEW

Abnormal Behavior Associated with a Point Mutation in the Structural Gene for Monoamine Oxidase A

1993 • 1,620 citations

Molecular Biology of Learning: Modulation of Transmitter Release

1982 • 1,534 citations

Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA

1995 • 1,211 citations

Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity

1992 • 1,126 citations

Enhanced Aggressive Behavior in Mice Lacking 5-HT _1B Receptor

1994 • 823 citations

A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia

1986 • 767 citations

Serotonin and Octopamine in the Nematode Caenorhabditis elegans

1982 • 575 citations

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons

1993 • 549 citations

SERUM VASOCONSTRICTOR (SEROTONIN)

1948 • 530 citations

Central Serotonin and Impulsive Aggression

1989 • 456 citations

Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys

1991 • 448 citations

Neurobiology of the Mauthner cell

1980 • 444 citations

Serotonergic facilitation of facial motoneuron excitation

1979 • 440 citations

Serotonin and Octopamine Produce Opposite Postures in Lobsters

1980 • 384 citations

Suicidality and 5-Hydroxyindoleacetic Acid Concentration Associated With a Tryptophan Hydroxylase Polymorphism

1994 • 378 citations

Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia

1992 • 377 citations

X-linked borderline mental retardation with prominent behavioral disturbance: phenotype, genetic localization, and evidence for disturbed monoamine metabolism.

1993 • 363 citations

Hormonal Control of Behavior: Amines and the Biasing of Behavioral Output in Lobsters

1988 • 355 citations

Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons

1993 • 353 citations

Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia

1992 • 313 citations

Serotonin Neurotransmission and Behavior

1982 • 309 citations

The Effect of Social Experience on Serotonergic Modulation of the Escape Circuit of Crayfish

1996 • 297 citations

Abnormal Fear Response and Aggressive Behavior in Mutant Mice Deficient for α-Calcium-Calmodulin Kinase II

1994 • 292 citations

Depletion of serotonin in the nervous system of Aplysia reduces the behavioral enhancement of gill withdrawal as well as the heterosynaptic facilitation produced by tail shock

1989 • 283 citations

Mapping of serotonin-like immunoreactivity in the lobster nervous system

1983 • 263 citations

Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in aplysia sensory neurons

1992 • 253 citations

Hyperphagia and Obesity Following Serotonin Depletion by Intraventricular p -Chlorophenylalanine

1976 • 241 citations

Serotonergic activation of tonic-type enteric neurons in guinea pig small bowel

1979 • 240 citations

Inhibitor of protein synthesis blocks longterm behavioral sensitization in the isolated gill‐withdrawal reflex of Aplysia

1989 • 240 citations

Effects of serotonin on the generation of the motor program for swimming by the medicinal leech

1981 • 238 citations

A molecular mechanism for long-term sensitization in Aplysia

1987 • 234 citations

Target-Dependent Structural Changes Accompanying Long-Term Synaptic Facilitation in Aplysia Neurons

1990 • 230 citations

Amines and A Peptide As Neurohormones in Lobsters: Actions on Neuromuscular Preparations and Preliminary Behavioural Studies

1980 • 224 citations

Identification and characterization of cerebral-to-buccal interneurons implicated in the control of motor programs associated with feeding in Aplysia

1991 • 222 citations

Octopamine and Some Related Noncatecholic Amines in Invertebrate Nervous Systems

1976 • 212 citations

A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia

1995 • 209 citations

Hyperphagia and Increased Growth in Rats After Intraventricular Injection of 5,7-Dihydroxytryptamine

1976 • 208 citations

The Structural Basis of an Innate Behavioural Pattern

1984 • 204 citations

Identified serotonergic neurons LCB1 and RCB1 in the cerebral ganglia of Aplysia produce presynaptic facilitation of siphon sensory neurons

1989 • 196 citations

Evidence for the 5-HT Hypothesis of Suicide A Review of Post-mortem Studies

1989 • 180 citations

Serotonin‐ and substance P‐containing projections to the nucleus tractus solitarii of the rat

1987 • 172 citations

Cellular mechanisms for modulation of posture by octopamine and serotonin in the lobster

1984 • 169 citations

Additional component in the cellular mechanism of presynaptic facilitation contributes to behavioral dishabituation in Aplysia.

1986 • 168 citations

Dynamic neuromodulation of synaptic strength intrinsic to a central pattern generator circuit

1994 • 165 citations

Serotonergic/cholinergic muscle receptor cells in the crab stomatogastric nervous system. I. Identification and characterization of the gastropyloric receptor cells

1989 • 165 citations

Neurotransmitter Actions in the Thalamus and Cerebral Cortex

1992 • 158 citations

Neurobiological mechanisms controlling aggression: Preclinical developments for pharmacotherapeutic interventions

1994 • 155 citations

Parallel processing of short‐term memory for sensitization in Aplysia

1988 • 153 citations

Targets of octopamine action in the lobster: cyclic nucleotide changes and physiological effects in hemolymph, heart and exoskeletal muscle.

1978 • 152 citations

The effects of octopamine and other amines on the heart and on neuromuscular transmission in decapod crustaceans: Further evidence for a role as neurohormone

1978 • 152 citations

Serotonin integrates the feeding behavior of the medicinal leech

1984 • 151 citations

Time course of structural changes at identified sensory neuron synapses during long-term sensitization in Aplysia

1989 • 150 citations

Brain monoaminergic control of male reproductive behavior. II. Dopamine and the post-ejaculatory refractory period

1984 • 143 citations

Serotonergic/cholinergic muscle receptor cells in the crab stomatogastric nervous system. II. Rapid nicotinic and prolonged modulatory effects on neurons in the stomatogastric ganglion

1989 • 143 citations

Postsynaptic 5-HT1 receptors and offensive aggression in rats: A combined behavioural and autoradiographic study with eltoprazine

1991 • 138 citations

The action of serotonin on excitatory nerve terminals in lobster nerve‐muscle preparations.

1982 • 136 citations

SEROTONIN AS A POSSIBLE NEUROHUMORAL AGENT: EVIDENCE OBTAINED IN LOWER ANIMALS

1957 • 129 citations

Activation of Lordotic Responding in Female Rats by Suppression of Serotonergic Activity

1973 • 128 citations

A Quantitative Analysis of Agonistic Behavior in Juvenile American Lobsters <i>(Homarus americanus L.)</i>

1995 • 128 citations

Biochemistry and ultrastructure of serotonergic nerve endings in the lobster: Serotonin and octopamine are contained in different nerve endings

1981 • 127 citations

Serotonergic innervation and modulation of the stomatogastric ganglion of three decapod crustaceans (Panulirus interruptus, Homarus americanus and Cancer irroratus)

1984 • 127 citations

The role of a modulatory neuron in feeding and satiation in Aplysia: effects of lesioning of the serotonergic metacerebral cells

1989 • 126 citations

Activity of an identified serotonergic neuron in free moving Aplysia correlates with behavioral arousal

1982 • 126 citations

5-HT modulation of hyperpolarization-activated inward current and calcium-dependent outward current in a crustacean motor neuron

1992 • 124 citations

Inter-male aggressive signals in weakly electric fish are modulated by monoamines

1987 • 122 citations

Serotonin and octopamine have opposite modulatory effects on the crayfish's lateral giant escape reaction

1983 • 122 citations

Relationship between dominance hierarchy, cerebrospinal fluid levels of amine transmitter metabolites (5-hydroxyindole acetic acid and homovanillic acid) and plasma cortisol in monkeys

1985 • 120 citations

5,7-Dihydroxytryptamine lesions of dorsal and median raphé nuclei and performance in the social interaction test of anxiety and in a home-cage aggression test

1979 • 119 citations

Octopamine release at two points along lobster nerve trunks.

1976 • 119 citations

Facilitatory transmitters and cAMP can modulate accommodation as well as transmitter release in Aplysia sensory neurons: Evidence for parallel processing in a single cell

1986 • 119 citations

Lateral Hypothalamic Control of Killing: Evidence for a Cholinoceptive Mechanism

1970 • 119 citations

Of mice and flies: commonalities among 5-HT receptors

1992 • 118 citations

Parachlorophenylalanine-induced serotonin depletion increases offensive but not defensive aggression in male rats

1986 • 117 citations

Activity of an identified histaminergic neuron, and its possible role in arousal of feeding behavior in semi-intact Aplysia

1986 • 113 citations

Serotonin, octopamine, and the clinging behavior induced by the parasite Polymorphus paradoxus (Acanthocephala) in Gammarus lacustris (Crustacea)

1990 • 113 citations

An Identified Neuron (CPR) Evokes Neuronal Responses Reflecting Food Arousal in Aplysia

1990 • 112 citations

Octopamine—a neurohormone with presynaptic activity-dependent effects at crayfish neuromuscular junctions

1983 • 108 citations

Imunocytochemical localization and direct assays of serotonin-containing neurons in Aplysia

1984 • 105 citations

Swim Initiation in the Leech by Serotonin-Containing Interneurones, Cells 21 and 61

1986 • 104 citations

Raphe Nuclei and the Serotonergic System

1990 • 102 citations

Neuromodulation of the crab pyloric central pattern generator by serotonergic/cholinergic proprioceptive afferents

1990 • 101 citations

Intrinsic neuromodulation in the Tritonia swim CPG: serotonin mediates both neuromodulation and neurotransmission by the dorsal swim interneurons

1995 • 98 citations

Distribution of serotonin-immunoreactive cell bodies and processes in the abdominal ganglion of mature Aplysia

1985 • 98 citations

Lateral Giant Fibers of Crayfish: Location of Somata by Dye Injection

1968 • 97 citations

Proctolin in identified serotonergic, dopaminergic, and cholinergic neurons in the lobster, Homarus americanus

1987 • 97 citations

Interganglionic cerebral-buccal mechanoafferents of Aplysia: receptive fields and synaptic connections to different classes of neurons involved in feeding behavior.

1982 • 97 citations

Actions of identified neuromodulatory neurons in a simple motor system

1990 • 96 citations

Development of Serotonergic Neurons in Embryos of the Sea Urchin, Strongylocentrotus purpuratus

1986 • 95 citations

Intrinsic neuromodulation in the Tritonia swim CPG: the serotonergic dorsal swim interneurons act presynaptically to enhance transmitter release from interneuron C2

1995 • 94 citations

An identified histaminergic neuron modulates feeding motor circuitry in Aplysia

1986 • 92 citations

Cholinergic synapses in the lateral hypothalamus for the control of predatory aggression in the rat

1970 • 92 citations

Serotonin immunoreactivity of neurons in the gastropod Aplysia californica

1986 • 92 citations

Biogenic amines as physiological regulators

1970 • 89 citations

Physiological identification, morphological analysis, and development of identified serotonin-proctolin containing neurons in the lobster ventral nerve cord

1987 • 88 citations

Conjoint action of phosphatidylinositol and adenylate cyclase systems in serotonin-induced facilitation at the crayfish neuromuscular junction

1989 • 82 citations

Reduction of Food Intake by Manipulation of Central Serotonin Current Experimental Results

1989 • 82 citations

Selective increase of offensive behavior in the rat following intrahypothalamic 5,7-DHT-induced serotonin depletion

1988 • 80 citations

Serotonin-containing neurons in lobsters: their role as gain-setters in postural control mechanisms

1992 • 80 citations

Inhibition of mouse killing behavior by serotonin-mimetic drugs: Effects of partial alterations of serotonin neurotransmission

1987 • 80 citations

Brain monoaminergic control of male reproductive behavior. I. Serotonin and the post-ejaculatory refractory period

1984 • 78 citations

Serotonergic modulation of the feeding behavior of the medicinal leech

1985 • 78 citations

Modulation of swimming in Tritonia: excitatory and inhibitory effects of serotonin

1994 • 76 citations

Critical Appraisal of the Evidence

1986 • 76 citations

Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.

1990 • 76 citations

Postsynaptic modifications in long-term facilitation in Aplysia: upregulation of excitatory amino acid receptors

1995 • 74 citations

Mapping of octopamine‐immunoreactive neurons in the central nervous system of the lobster

1993 • 73 citations

Serotonergic stretch receptors induce plateau properties in a crustacean motor neuron by a dual-conductance mechanism

1992 • 73 citations

Serotonin Analog Selectively Ablates Indentified Neurons in the Leech Embryo

1982 • 72 citations

The dual role of serotonin in leech swimming.

1982 • 71 citations

Peripheral modulation of mechanosensitivity in primary afferent neurons

1987 • 68 citations

Calcium-dependent plateau potentials in a crab stomatogastric ganglion motor neuron. II. Calcium-activated slow inward current

1995 • 68 citations

Integrative Neurophysiology of the Lobster Cardiac Ganglion

1979 • 65 citations

Mauthner axon networks mediating supraspinal components of the startle response in the goldfish

1983 • 65 citations

Identified facilitator neurons L29 and L28 are excited by cutaneous stimuli used in dishabituation, sensitization, and classical conditioning of Aplysia

1989 • 64 citations

Serotonin in the leech central nervous system: anatomical correlates and behavioral effects

1991 • 62 citations

Multiple receptors mediate the modulatory effects of serotonergic neurons in a small neural network

1994 • 61 citations

The effects of intraventricular administration of eltoprazine, 1-(3-trifluoromethylphenyl) piperazine hydrochloride and 8-hydroxy-2-(di-n-propylamino) tetralin on resident intruder aggression in the rat

1992 • 61 citations

Serotonin and contractile activity in the echinopluteus

1972 • 59 citations

Long-term Facilitation in Aplysia: Persistent Phosphorylation and Structural Changes

1990 • 59 citations

Serotonin, suicide, and aggression: clinical studies.

1991 • 58 citations

Recruitment of crab gastric mill neurons into the pyloric motor pattern by mechanosensory afferent stimulation

1991 • 57 citations

Effect of hypothalamic injections of 5,7-dihydroxytryptamine on elicitation of mouse-killing in rats

1982 • 57 citations

Modulation of swimming behavior in the medicinal leech

1993 • 57 citations

Localization of potential serotonergic facilitator neurons in Aplysia by glyoxylic acid histofluorescence combined with retrograde fluorescent labeling

1989 • 56 citations

Serotonin‐immunoreactive neurons in the cnidarian Renilla koellikeri

1990 • 55 citations

Does the Mauthner cell conform to the criteria of the command neuron concept?

1981 • 54 citations

Calcium-dependent plateau potentials in a crab stomatogastric ganglion motor neuron. I. Calcium current and its modulation by serotonin

1995 • 54 citations

Modulatory synaptic actions of an identified histaminergic neuron on the serotonergic metacerebral cell of Aplysia

1986 • 53 citations

Sensory function and gating of histaminergic neuron C2 in Aplysia.

1986 • 53 citations

Monoamine systems in the cerebral cortex: evidence for anatomical specificity

1991 • 51 citations

Intrahypothalamic 5,7-dihydroxytryptamine facilitates feminine sexual behavior and decreases [3H]imipramine binding and 5-HT uptake

1983 • 51 citations

Histochemical Localization of Amines in Hydra and in the Sea Anemone

1964 • 51 citations

Identified cholinergic neurons R2 and LPl1 control mucus release in Aplysia

1983 • 50 citations

A cytochemical study of the serotoninergic, cholinergic and peptidergic components of the reproductive system in the monogenean parasite,Diclidophora merlangi

1990 • 48 citations

Cyclic AMP only partially mediates the actions of serotonin at lobster neuromuscular junctions

1989 • 48 citations

Lesion of a serotonergic modulatory neuron inAplysia produces a specific defect in feeding behavior

1983 • 46 citations

Phosphatidylinositol system's role in serotonin-induced facilitation at the crayfish neuromuscular junction

1989 • 45 citations

Serotonin and Leech Feeding Behavior: Obligatory Neuromodulation

1989 • 44 citations

5,7-Dihydroxytryptamine lesions of crayfish serotonin-containing neurons: effect on the lateral giant escape reaction

1986 • 44 citations

Sensory function and gating of histaminergic neuron C2 in Aplysia

1986 • 42 citations

Amine modulation of extension command element-evoked motor activity in the lobster abdomen

1985 • 41 citations

Postsynaptic modulation of rectifying electrical synaptic inputs to the LG escape command neuron in crayfish

1991 • 40 citations

Crayfish tonic inhibition: prolonged modulation of behavioral excitability by classical GABAergic inhibition

1993 • 39 citations

Modulation of swimming behavior in the medicinal leech

1994 • 39 citations

Modulation of a rhythmic activity by serotonin via cyclic AMP in the coelenterateRenilla k�llikeri

1989 • 39 citations

Serotonergic facilitation of quantal release at central inhibitory synapses

1991 • 38 citations

On the termination of ingestive behaviour by the medicinal leech

1987 • 36 citations

Synaptic Basis of Swim Initiation in the Leech: III. Synaptic Effects of Serotonin-Containing Interneurones (Cells 21 and 61) on Swim Cpg Neurones (Cells 18 and 208)

1986 • 35 citations

Effect of Serotonergic Afferents on Quantal Release at Central Inhibitory Synapses

1989 • 34 citations

Bidirectional Relationships Between Tryptophan and Social Behavior in Vervet Monkeys

1991 • 33 citations

Studies on motilityin vitroof an ectoparasitic monogenean,Diclidophora merlangi

1989 • 32 citations

Widespread mechanosensory activation of the serotonergic system of the medicinal leech

1995 • 30 citations

THE BIOCHEMICAL BASIS OF NEUROPHARMACOLOGY

1975 • 29 citations

The Behavioural State of Satiation in the Leech is Regulated by Body Distension and Mimicked by Serotonin Depletion

1993 • 26 citations

Inhaled nitric oxide in chronic obstructive lung disease

1993 • 22 citations

Manual of Clinical Psychopharmacology

1991 • 22 citations

Occurrence of 5-hydroxytryptamine (serotonin) in the nervous system of a monogenean, Diclidophora merlangi

1987 • 18 citations

Activity of identified cerebral neuron correlates with food-induced arousal in Aplysia

1991 • 17 citations

The participation of serotoninergic system in the regulation of emotional-defensive behavior evoked by intrahypothalamic carbachol injections in the cat.

1985 • 14 citations

[3H]Serotonin binding to blastula, gastrula, prism, and pluteus sea urchin embryo cells

1989 • 8 citations

Determination of 5-hydroxytryptamine in early echinoderm embryos

1977 • 8 citations

Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus.

1990 • 6 citations