Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

1983 • 2,290 citations

The Biochemical Basis of Neuropharmacology.

1974 • 1,911 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

1991 • 928 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

[20] Isolation of RNA using guanidinium salts

1987 • 614 citations

Cloning of a Serotonin Transporter Affected by Antidepressants

1991 • 613 citations

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

1992 • 594 citations

Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides

1982 • 478 citations

Tritiated Imipramine Binding Sites Are Decreased in Platelets of Untreated Depressed Patients

1980 • 440 citations

The Biochemical Basis of Neuropharmacology

2002 • 294 citations

Molecular cloning and expression of a high affinity l -proline transporter expressed in putative glutamatergic pathways of rat brain

1992 • 239 citations

The peripheral actions of 5-Hydroxytryptamine

1990 • 234 citations

Active transport of 5-hydroxytryptamine by plasma membrane vesicles isolated from human blood platelets.

1977 • 224 citations

Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake.

1972 • 186 citations

Cloning of the human brain GABA transporter

1990 • 177 citations

Serotonin Uptake and Serotonin Uptake Inhibition

1990 • 176 citations

Evidence for an Imipramine-sensitive Serotonin Transporter in Human Placental Brush-border Membranes

1989 • 158 citations

Vaccinia-T7 RNA polymerase expression system: Evaluation for the expression cloning of plasma membrane transporters

1991 • 157 citations

Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR)

1991 • 143 citations

Accumulation of tritiated 5-hydroxytryptamine in brain slices

1967 • 131 citations

[125I]RTI-55: a potent ligand for dopamine transporters

1991 • 125 citations

The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4.

1985 • 111 citations

Platelet 5-hydroxytryptamine transport, an electroneutral mechanism coupled to potassium

1978 • 108 citations

Binding of some antidepressants to the 5-hydroxytryptamine transporter in brain and platelets

1990 • 96 citations

Serotonin uptake and imipramine binding in the blood platelets of obsessive-compulsive disorder patients

1991 • 64 citations

Biological Aspects of Affective Disorders

1991 • 64 citations

Serotonin uptake by bovine pulmonary artery endothelial cells in culture. I. Characterization

1986 • 57 citations

Translocation of protein kinase C is associated with inhibition of 5-HT uptake by cultured endothelial cells

1989 • 53 citations

Uptake of [3H]serotonin into plasma membrane vesicles from mouse cerebral cortex.

1988 • 51 citations

Isolation of cDNAs encoding a novel member of the neurotransmitter transporter gene family

1991 • 43 citations

Modulation of serotonin uptake kinetics by ions and ion gradients in human placental brush-border membrane vesicles

1990 • 42 citations

A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter

1989 • 42 citations

Role of ions and membrane potential in uptake of serotonin into plasma membrane vesicles from mouse brain

1989 • 35 citations

Antidepressant binding to the porcine and human platelet serotonin transporters.

1988 • 35 citations

Sodium-dependent neurotransmitter reuptake systems

1991 • 35 citations

Brain systems, disorders and psychotropic drugs

1988 • 28 citations

Drug inhibition indicates a single-site model of the 5-HT uptake site/antidepressant binding site in rat and human brain

1989 • 21 citations

Inactivation of the human placental serotonin transporter by tyrosyl group-specific reagents.

1989 • 20 citations