Regulation of Antidepressant-Sensitive Serotonin Transporters

Psychopharmacology: The Fourth Generation of Progress

1995 • 2,920 citations

Structure and function of the brain serotonin system

1992 • 2,507 citations

Neuropsychopharmacology

1990 • 1,545 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

1991 • 928 citations

Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter

1994 • 904 citations

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 • 883 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

Psychopharmacology: The Fourth Generation of Progress

1996 • 755 citations

Organization of the human serotonin transporter gene

1994 • 623 citations

Cloning of a Serotonin Transporter Affected by Antidepressants

1991 • 613 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Primary Structure of the Human Platelet Serotonin Uptake Site: Identity with the Brain Serotonin Transporter

1993 • 543 citations

The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons

1996 • 473 citations

Molecular Physiology of Norepinephrine and Serotonin Transporters

1994 • 404 citations

HORMONAL REGULATION OF MAMMALIAN GLUCOSE TRANSPORT

1986 • 399 citations

Cloning and functional characterization of a cocaine‐sensitive dopamine transporter

1991 • 362 citations

Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract

1996 • 331 citations

Stimulation of astroglial 5-HT1A receptors releases the serotonergic growth factor, protein S-100, and alters astroglial morphology

1990 • 317 citations

Conducting states of a mammalian serotonin transporter

1994 • 286 citations

Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling

1993 • 274 citations

Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine.

1987 • 264 citations

Cloning of the cocaine-sensitive bovine dopamine transporter.

1991 • 261 citations

Serotonin and the Cardiovascular System

1985 • 255 citations

Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies

1995 • 253 citations

Specific tricyclic antidepressant binding sites in rat brain characterised by high-affinity 3H-imipramine binding

1980 • 249 citations

Role of Serotonin in Depression^a

1990 • 239 citations

The peripheral actions of 5-Hydroxytryptamine

1990 • 234 citations

S-100B but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factor

1990 • 230 citations

Interleukin 1 receptors in the brain and endocrine tissues

1993 • 228 citations

Isolation of a cDNA encoding the human brain serotonin transporter

1993 • 223 citations

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

1994 • 211 citations

Regional brain expression of serotonin transporter mRNA and its regulation by reuptake inhibiting antidepressants

1993 • 210 citations

Tianeptine, a selective enhancer of serotonin uptake in rat brain

1987 • 209 citations

Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP.

1994 • 194 citations

Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene

1993 • 194 citations

Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin

1993 • 186 citations

Desensitization of the neuronal 5-HT carrier following its long-term blockade

1994 • 182 citations

Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster.

1994 • 181 citations

A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization.

1994 • 179 citations

Serotonin Uptake and Serotonin Uptake Inhibition

1990 • 176 citations

Distinct regulatory pathways control neurofilament expression and neurotransmitter synthesis in immortalized serotonergic neurons

1994 • 171 citations

Sodium-Dependent Norepinephrine-Induced Currents in Norepinephrine-Transporter-Transfected Hek-293 Cells Blocked by Cocaine and Antidepressants

1995 • 169 citations

Serotonin as a regulator of craniofacial morphogenesis: Site specific malformations following exposure to serotonin uptake inhibitors

1992 • 166 citations

Evidence for an Imipramine-sensitive Serotonin Transporter in Human Placental Brush-border Membranes

1989 • 158 citations

Regulation of the Human Serotonin Transporter by Interleukin-1β

1995 • 156 citations

Serotonin Receptor Subtypes

1995 • 149 citations

A GABA transporter operates asymmetrically and with variable stoichiometry

1994 • 146 citations

Modulation of neuronal serotonin uptake by a putative endogenous ligand of imipramine recognition sites.

1983 • 145 citations

Cloning and expression of the mouse serotonin transporter

1996 • 144 citations

Serotonin and the cardiovascular system

1985 • 143 citations

Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR)

1991 • 143 citations

Stimulation of astroglial serotonin receptors produces culture media which regulates growth of serotonergic neurons

1989 • 142 citations

Developmental Regulation of Early Serotonergic Neuronal Differentiation: The Role of Brain-Derived Neurotrophic Factor and Membrane Depolarization

1995 • 128 citations

Tianeptine stimulates uptake of 5-hydroxytryptamine in vivo in the rat brain

1990 • 127 citations

Effects of p-chlorophenylalanine on time of neuronal origin during embryo-genesis in the rat

1976 • 125 citations

Towards an understanding of the signal transduction pathways for interleukin 1

1995 • 123 citations

S‐100β and insulin‐like growth factor‐II differentially regulate growth of developing serotonin and dopamine neurons in vitro

1992 • 122 citations

Cell-specific Sorting of Biogenic Amine Transporters Expressed in Epithelial Cells

1996 • 121 citations

Primary structure of the serotonin transporter in unipolar depression and bipolar disorder

1995 • 121 citations

Human norepinephrine transporter. Biosynthetic studies using a site-directed polyclonal antibody.

1994 • 119 citations

Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding.

1993 • 117 citations

Cloning and expression of the bovine sodium‐ and chloride‐dependent noradrenaline transporter

1994 • 116 citations

The transport of neurotransmitters into synaptic vesicles

1992 • 113 citations

Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells.

1994 • 104 citations

Activators of protein kinase C decrease serotonin transport in human platelets

1992 • 102 citations

Serotonin uptake in the ectoplacental cone and placenta of the mouse

1993 • 101 citations

Regulation of Glucose-Transporter Function

1990 • 99 citations

Neurochemical profile of tianeptine, a new antidepressant drug.

1988 • 99 citations

Linkage mapping of serotonin transporter protein gene SLC6A4 on chromosome 17

1995 • 97 citations

Down regulation of dihydroalprenolol and imipramine binding sites in brain of rats repeatedly treated with imipramine

1980 • 95 citations

The effect of chronic imipramine administration on the densities of 5-HT1A and 5-HT2 receptors and the abundancies of 5-HT receptor and transporter mRNA in the cortex, hippocampus and dorsal raphe of three strains of rat

1994 • 94 citations

Hypothalamic and Suprachiasmatic Uptake of Serotonin in Vitro: Twenty-Four-Hour Changes in Male and Proestrous Female Rats

1976 • 93 citations

Effects of adrenalectomy and type I or type II glucocorticoid receptor activation on 5-HT1A and 5-HT2 receptor binding and 5-HT transporter mRNA expression in rat brain

1994 • 91 citations

Expression of Serotonin Transporter Messenger RNA in the Human Brain

1994 • 83 citations

Pharmacological antidepressive effects and tianeptine-induced 5-HT uptake increase.

1988 • 80 citations

[3H]Paroxetine Binding and Serotonin Content of Rat Cortical Areas, Hippocampus, Neostriatum, Ventral Mesencephalic Tegmentum, and Midbrain Raphe Nuclei Region Following p‐Chlorophenylalanine and p‐Chloroamphetamine Treatment

1992 • 79 citations

Concomitant decrease in [3H]imipramine binding in cat brain and platelets after chronic treatment with imipramine

1982 • 75 citations

Serotonin initiates and autoamplifies its own synthesis during mouse central nervous system development.

1986 • 74 citations

Transient midline raphe glial structure in the developing rat

1986 • 74 citations

The effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo

1991 • 70 citations

Regulation of angiotensin II binding sites in neuronal cultures by catecholamines

1989 • 68 citations

Synaptic properties of serotonergic growth cones in developing rat brain

1994 • 65 citations

Effect of antidepressant drugs on monoamine synthesis in brain in vivo

1992 • 65 citations

The Influence of Cholesteryl Ester Transfer Protein on the Composition, Size, and Structure of Spherical, Reconstituted High Density Lipoproteins

1995 • 65 citations

Serotonin transporter mRNA in rat brain is regulated by classical antidepressants

1994 • 64 citations

Effect of chronic treatment with selective monoamine oxidase inhibitors and specific 5-hydroxytryptamine uptake inhibitors on [3h]paroxetine binding to cerebral cortical membranes of the rat

1987 • 62 citations

Fibroblast Growth Factor‐5 Promotes Differentiation of Cultured Rat Septal Cholinergic and Raphe Serotonergic Neurons: Comparison with the Effects of Neurotrophins

1994 • 61 citations

Expression of a Serotonin-Gated Ion Channel in Embryonic Neural and Nonneural Tissues

1995 • 59 citations

Chapter 27 ACTH neuropeptide stimulation of serotonergic neuronal maturation in tissue culture: modulation by hippocampal cells

1987 • 57 citations

Cyclic AMP-independent Up-regulation of the Human Serotonin Transporter by Staurosporine in Choriocarcinoma Cells

1995 • 55 citations

Translocation of protein kinase C is associated with inhibition of 5-HT uptake by cultured endothelial cells

1989 • 53 citations

Regulation of high- and low-affinity [3H]imipramine recognition sites in rat brain by chronic treatment with antidepressants

1987 • 50 citations

The effect of ovarian steroids on the accumulation of3H-labelled monoamines by hypothalamic tissuein vitro

1974 • 49 citations

Serotonin uptake, storage, and synthesis in an immortalized committed cell line derived from mouse teratocarcinoma.

1990 • 49 citations

Serotonin depletion decreases serotonin transporter mRNA levels in rat brain

1995 • 48 citations

Autoradiographic analyses of the effects of estradiol benzoate on [3H]paroxetine binding in the cerebral cortex and dorsal hippocampus of gonadectomized male and female rats

1993 • 47 citations

DIfferential effects of prenatal and postnatal acth or nicotine exposure on 5‐HT high affinity uptake in the neonatal rat brain

1991 • 46 citations

Neuronal properties of a thyroid C-cell line: partial repression by dexamethasone and retinoic acid.

1992 • 44 citations

The effect of oestradiol dipropionate and progesterone on monoamioe uptake in rat brain¹

1974 • 44 citations

CHANGES IN HYPOTHALAMIC NORADRENALINE, DOPAMINE AND SEROTONIN UPTAKE AFTER OESTRADIOL ADMINISTRATION TO RATS

1977 • 43 citations

In vivo studies on the enhancement of serotonin reuptake by tianeptine

1992 • 43 citations

Increase of human platelet serotonin uptake by atypical histamine receptors

1994 • 43 citations

Induction of a serotonergic and neuronal phenotype in thyroid C-cells

1995 • 40 citations

Tianeptine decreases both serotonin transporter mRNA and binding sites in rat brain

1994 • 39 citations

(−)-deprenyl a selective mao ‘B’ inhibitor increases [3H]imipramine binding and decreases β-adrenergic receptor function

1983 • 36 citations

Long-term regulation of serotonergic activity in the rat brain via activation of protein kinase A.

1993 • 36 citations

Novel environment and cat odor change GABA and 5-HT release and uptake in the rat

1993 • 34 citations

Effect of repeated administration of antidepressants on serotonin uptake sites in limbic and neocortical structures of rat brain determined by quantitative autoradiography.

1992 • 33 citations

Acute depletion of serotonin down-regulates serotonin transporter mRNA in raphe neurons

1995 • 33 citations

Increased expression of serotonin transporter messenger RNA in raphe neurons of the aged rat

1995 • 31 citations

Murine serotonin transporter: sequence and localization to Chromosome 11

1993 • 28 citations

Hypoxia Directly Increases Serotonin Transport by Porcine Pulmonary Artery Endothelial Cell Plasma Membrane Vesicles

1990 • 25 citations

Drug Targets in the Embryo

1996 • 25 citations

Adrenocorticotropic hormone activation of adenylate cyclase in raphe neurons: Multiple regulatory pathways control serotonergic neuronal differentiation

1995 • 23 citations

Effect of Different Photoperiod Exposure on [³H]Imipramine Binding and Serotonin Uptake in the Rat Brain

1989 • 23 citations

Diurnal Variation in the Function of Serotonin Terminals in the Rat Hypothalamus

1989 • 23 citations

Role of calcium ion in platelet serotonin uptake regulation

1995 • 21 citations

Neuronal properties of a thyroid C-cell line: partial repression by dexamethasone and retinoic acid

1992 • 19 citations

Expression and development of a functional plasmalemmal 5-hydroxytryptamine transporter by thyroid follicular cells.

1996 • 15 citations

Lithium treatment regimens induce different changes in [3H]paroxetine binding protein and other rat brain proteins

1992 • 14 citations

Selective effect of phorbol ester on serotonin removal and ACE activity in rabbit lungs

1988 • 13 citations

Pulmonary angiotensin-converting enzyme kinetics after acute lung injury in the rabbit

1988 • 13 citations

Effect of concanavalin a on 3H-5-hydroxytryptamine uptake in rabbit blood platelets: Interaction with adenylate cyclase activity.

1983 • 10 citations

Kinase inhibitors compete with imipramine for binding and inhibition of serotonin transport

1994 • 8 citations

Effect of Concanavalin A on Serotonin Transport into Blood Platelets: Possible Involvement of Protein Kinase C

1990 • 6 citations