The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity

1988 • 548 citations

Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake

1984 • 528 citations

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.

1987 • 526 citations

Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: A regional study

1980 • 492 citations

3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.

1987 • 455 citations

Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain.

1980 • 444 citations

The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain

1986 • 354 citations

In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain

1987 • 301 citations

Effects of certain hallucinogenic amphetamine analogs on the release of [3H]-serotonin from rat brain synaptosomes

1982 • 180 citations

Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain

1987 • 180 citations

Biology of Serotonergic Transmission

1983 • 166 citations

Fluoxetine and two other serotonin uptake inhibitors without affinity for neuronal receptors

1983 • 166 citations

Mechanisms of effects of d-Fenfluramine on brain serotonin metabolism in rats: Uptake inhibition versus release

1988 • 157 citations

Anatomic evidence for a neurotoxic effect of (±)-fenfluramine upon serotonergic projections in the rat

1990 • 121 citations

Kinetics of serotonin accumulation into synaptosomes of rat brain-effects of amphetamine and chloroamphetamines

1973 • 117 citations

Reversible and irreversible phases of serotonin depletion by 4-chloroamphetamine

1975 • 109 citations

IMMEDIATE AND LONG‐TERM EFFECTS OF p‐CHLOROAMPHETAMINE ON BRAIN AMINES*

1978 • 106 citations

5-Hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents

1990 • 106 citations

Neuroendocrine and Mood Responses to Intravenous L-Tryptophan in 3,4-Methylenedioxymethamphetamine (MDMA) Users

1989 • 92 citations

3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine

1991 • 91 citations

Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies.

1989 • 82 citations

The Mechanism of Action of Indirectly Acting Sympathomimetic Amines

1988 • 80 citations

Differences Between d‐Fenfluramine and d‐Norfenfluramine in Serotonin Presynaptic Mechanisms

1983 • 73 citations

MDMA (ecstasy) effects on cultured serotonergic neurons: evidence for Ca2+-dependent toxicity linked to release

1990 • 67 citations

EFFECT OF FENFLURAMINE ON 5‐HYDROXYTRYPTAMINE UPTAKE AND RELEASE BY RAT BLOOD PLATELETS

1975 • 65 citations

Antagonism of the Acute and Long–term Biochemical Effects of 4–Chloroamphetamine on the 5–HT Neurones in the Rat Brain by Inhibitors of the 5–Hydroxytryptamine Uptake

1976 • 58 citations

Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: application to methylenedioxymethamphetamine.

1988 • 54 citations

Hyperthermia Induced by Amphetamine, p-Chloroamphetamine and Fenfluramine in the Rat

1975 • 51 citations

Carrier-mediated and carrier-independent release of serotonin from isolated central nerve endings

1982 • 49 citations

Comparative actionof fenfluramine on the uptake and release of serotonin and dopamine

1976 • 49 citations

Role of the serotonin uptake carrier in the neurochemical response to methamphetamine: Effects of citalopram and chlorimipramine

1985 • 46 citations

Mechanism by which uptake inhibitors antagonizep-chloroamphetamine-induced depletion of brain serotonin

1980 • 42 citations

Coincidence of blockade of synaptosomal 5-hydroxytryptamine uptake and decrease in tryptophan hydroxylase activity: effects of fenfluramine.

1976 • 34 citations

Depletion of serotonin using p-chlorophenylalanine (PCPA) and reserpine protects against the neurotoxic effects of p-chloroamphetamine (PCA) in the brain

1989 • 30 citations

STRUCTURE‐ACTIVITY RELATIONSHIPS AMONG THE HALOGENATED AMPHETAMINES

1978 • 30 citations

Differential effects of d-fenfluramine and p-chloroamphetamine on H7512-induced depletion of 5-hydroxytryptamine and dopamine in the rat brain

1991 • 29 citations

Structural Requirements for Uptake into Serotoninergic Neurones

1980 • 29 citations

Substituted Amphetamine Derivatives. I. Effect on Uptake and Release of Biogenic Monoamines and on Monoamine Oxidase in the Mouse Brain

1977 • 24 citations

Effects of mazindol, fenfluramine and chlorimipramine on the 5-hydroxytryptamine uptake and storage mechanisms in rat brain: Similarities and differences

1977 • 24 citations

Specificity of release of biogenic amines from isolated rat brain tissue as a function of the meta substituent of N-ethylamphetamine derivatives.

1976 • 17 citations

Zimelidine and clomipramine: Different influence on fenfluramine but not p-chloroamphetamine-induced pharmacological effects

1980 • 16 citations

Effects of fenfluramine on accumulation of 5-hydroxytryptamine and other neurotransmitters into synaptosomes of rat brain

1976 • 12 citations

Drug-induced release of biogenic amines from synaptosomes and blood platelets of guinea-pigs

1982 • 6 citations

SECTION OF GEOLOGY AND MINERALOGY: THE PRECAMBRIAN‐CAMBRIAN PROBLEM OF EAST NEWFOUNDLAND*

1950 • 5 citations

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