Cell Migration and Signaling Specificity Is Determined by the Phosphatidylserine Recognition Motif of Rac1

Rho GTPases in cell biology

2002 • 4,662 citations

Rho and Rac Take Center Stage

2004 • 1,797 citations

The Guanine Nucleotide-Binding Switch in Three Dimensions

2001 • 1,779 citations

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

2005 • 1,680 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Cell migration: Rho GTPases lead the way

2003 • 1,412 citations

Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases

1999 • 765 citations

Endomembrane Trafficking of Ras

1999 • 753 citations

Differential Localization of Rho Gtpases in Live Cells

2001 • 686 citations

The ins and outs of lysophosphatidic acid signaling

2004 • 550 citations

Rho Guanine Dissociation Inhibitors

1999 • 487 citations

Metabolism and functions of phosphatidylserine

2005 • 464 citations

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

1997 • 422 citations

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

2000 • 356 citations

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

2002 • 326 citations

Lipid–protein interactions in blood coagulation

1998 • 288 citations

Capacitation Induces Cyclic Adenosine 3′,5′-Monophosphate-Dependent, but Apoptosis-Unrelated, Exposure of Aminophospholipids at the Apical Head Plasma Membrane of Boar Sperm Cells1

2002 • 258 citations

Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids.

1994 • 233 citations

Rac-PAK Signaling Stimulates Extracellular Signal-Regulated Kinase (ERK) Activation by Regulating Formation of MEK1-ERK Complexes

2002 • 219 citations

Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes

2005 • 214 citations

The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences

2003 • 209 citations

Molecular Dissection of a Yeast Septin: Distinct Domains Are Required for Septin Interaction, Localization, and Function

2003 • 206 citations

The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras

1994 • 202 citations

The DIX domain targets dishevelled to actin stress fibres and vesicular membranes

2002 • 193 citations

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1997 • 192 citations

Rho Proteins and Cancer

2004 • 188 citations

Membrane Binding of Myristylated Peptides Corresponding to the NH2 Terminus of Src

1994 • 154 citations

Targeting of Rac1 to the Phagocyte Membrane Is Sufficient for the Induction of NADPH Oxidase Assembly

2000 • 131 citations

PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway

2002 • 121 citations

The Rac1 C-terminal Polybasic Region Regulates the Nuclear Localization and Protein Degradation of Rac1

2004 • 106 citations

Lipid Products of Phosphoinositide 3-Kinase Interact with Rac1 GTPase and Stimulate GDP Dissociation

1998 • 103 citations

The C-terminal Domain of Rac1 Contains Two Motifs That Control Targeting and Signaling Specificity

2003 • 101 citations

Osmotic Response Element Enhancer Activity

1999 • 85 citations

Insulin Stimulation of a MEK-Dependent but ERK-Independent SOS Protein Kinase

1996 • 82 citations

Phospholipids Can Switch the GTPase Substrate Preference of a GTPase-activating Protein

2004 • 76 citations

Mechanism of Mitosis-specific Activation of MEK1

2003 • 53 citations

Mapping the lipid distribution in the membranes of BHK cells (Mini-Review)

1996 • 52 citations

Activation of the O^–₂‐Generating NADPH Oxidase in a Semi–Recombinant Cell‐Free System

1994 • 44 citations

Specific Interaction of Protein Tyrosine Phosphatase-MEG2 with Phosphatidylserine

2003 • 34 citations

Structural and Biophysical Insights into the Role of the Insert Region in Rac1 Function

2002 • 32 citations

Secondary Structure, 1H, 13C and 15N Resonance Assignments and Molecular Interactions of the Dishevelled DIX Domain

2005 • 8 citations

The GTPase Cycle: How Dominant Inhibitory Mutants Block the Biological Functions of Small GTPases

2003 • 4 citations