Structural and Biophysical Insights into the Role of the Insert Region in Rac1 Function

Pure absorption gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity

1992 • 2,231 citations

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

1994 • 648 citations

The Small GTPase Rho: Cellular Functions and Signal Transduction

1996 • 404 citations

Signaling and Subcellular Targeting by Membrane-Binding Domains

2000 • 259 citations

Crystal Structure of Human RhoA in a Dominantly Active Form Complexed with a GTP Analogue

1998 • 214 citations

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

1991 • 211 citations

Increasing Complexity of Ras Signal Transduction: Involvement of Rho Family Proteins

1997 • 185 citations

Rac Binding to p67

1997 • 135 citations

Lipid Products of Phosphoinositide 3-Kinase Interact with Rac1 GTPase and Stimulate GDP Dissociation

1998 • 103 citations

p21 with a phenylalanine 28—-leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties.

1991 • 102 citations

Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)

2001 • 64 citations

Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1

2000 • 47 citations

Loop 6 of RhoA Confers Specificity for Effector Binding, Stress Fiber Formation, and Cellular Transformation

1999 • 42 citations

The Insert Region of Rac1 Is Essential for Membrane Ruffling but Not Cellular Transformation

2001 • 40 citations