SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs

Transcriptional Activation by Tetracyclines in Mammalian Cells

1995 • 2,458 citations

Sorting out the complexity of SR protein functions

2000 • 1,064 citations

Alternative pre-mRNA splicing: the logic of combinatorial control

2000 • 892 citations

The superfamily of arginine/serine-rich splicing factors.

1995 • 671 citations

SR proteins and splicing control.

1996 • 668 citations

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

1994 • 612 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities.

1995 • 351 citations

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

1998 • 334 citations

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.

1994 • 321 citations

A Regulatory Mechanism That Detects Premature Nonsense Codons in T-cell Receptor Transcripts in Vivo Is Reversed by Protein Synthesis Inhibitors in Vitro

1995 • 317 citations

Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

1995 • 282 citations

Initial splice-site recognition and pairing during pre-mRNA splicing

1996 • 281 citations

The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation

1997 • 264 citations

Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

1992 • 244 citations

Exonic Splicing Enhancer Motif Recognized by Human SC35 under Splicing Conditions

2000 • 243 citations

Selection and Characterization of Pre-mRNA Splicing Enhancers: Identification of Novel SR Protein-Specific Enhancer Sequences

1999 • 232 citations

Determinants of SR protein specificity

1999 • 224 citations

The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers

1999 • 223 citations

Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability.

1996 • 200 citations

Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

1993 • 200 citations

Multiple Distinct Splicing Enhancers in the Protein-Coding Sequences of a Constitutively Spliced Pre-mRNA

1999 • 191 citations

Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans

2000 • 187 citations

atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes

1999 • 164 citations

Substrate Specificities of SR Proteins in Constitutive Splicing Are Determined by Their RNA Recognition Motifs and Composite Pre-mRNA Exonic Elements

1999 • 146 citations

Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors

1998 • 144 citations

The SR splicing factors ASF/SF2 and SC35 have antagonistic effects on intronic enhancer-dependent splicing of the beta -tropomyosin alternative exon 6A

1997 • 124 citations

Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila.

1991 • 102 citations

Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing

1998 • 100 citations

smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans

1997 • 92 citations

A potential splicing factor is encoded by the opposite strand of the trans-spliced c-myb exon.

1992 • 89 citations

Nonsense Codons Can Reduce the Abundance of Nuclear mRNA without Affecting the Abundance of Pre-mRNA or the Half-Life of Cytoplasmic mRNA

1993 • 82 citations

Identification of a Bidirectional Splicing Enhancer: Differential Involvement of SR Proteins in 5′ or 3′ Splice Site Activation

1999 • 78 citations

Antagonism between RSF1 and SR proteins for both splice-site recognition in vitro and Drosophila development

1999 • 57 citations

The concentration of B52, an essential splicing factor and regulator of splice site choice in vitro, is critical for Drosophila development.

1994 • 57 citations

The Gene Encoding Human Splicing Factor 9G8

1995 • 42 citations

Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.

1994 • 34 citations

Characterization of SRp46, a Novel Human SR Splicing Factor Encoded by a PR264/SC35 Retropseudogene

1998 • 32 citations

Pre-mRNA Splicing by the Essential Drosophila Protein B52: Tissue and Target Specificity

2000 • 31 citations

The Concentration of B52, an Essential Splicing Factor and Regulator of Splice Site Choice In Vitro, Is Critical for Drosophila Development

1994 • 30 citations

Analysis of autoregulation at the level of pre-mRNA splicing of the suppressor-of-white-apricot gene in Drosophila.

1994 • 25 citations