TWEAK Induces NF-κB2 p100 Processing and Long Lasting NF-κB Activation

NF-κB regulation in the immune system

2002 • 3,804 citations

Missing Pieces in the NF-κB Puzzle

2002 • 3,560 citations

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

NF-κB at the crossroads of life and death

2002 • 2,684 citations

NF-κB in cancer: from innocent bystander to major culprit

2002 • 2,457 citations

Plat-E: an efficient and stable system for transient packaging of retroviruses

2000 • 1,614 citations

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

2001 • 1,333 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 • 1,070 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

NF-κB signaling pathways in mammalian and insect innate immunity

2001 • 892 citations

The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways

2002 • 891 citations

NF-κB-Inducing Kinase Regulates the Processing of NF-κB2 p100

2001 • 807 citations

BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells

2002 • 674 citations

TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis

1997 • 666 citations

BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2

2002 • 468 citations

Selective activation of NF-κB subunits in human breast cancer: potential roles for NF-κB2/p52 and for Bcl-3

2000 • 451 citations

CD40 regulates the processing of NF-kappaB2 p100 to p52

2002 • 435 citations

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50

1991 • 403 citations

Two Pathways to NF-κB

2002 • 383 citations

A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis

2001 • 364 citations

The TNF-receptor-associated factor family

2001 • 344 citations

Applications of retrovirus-mediated expression cloning.

1996 • 339 citations

Critical Roles of TRAF2 and TRAF5 in Tumor Necrosis Factor-induced NF-κB Activation and Protection from Cell Death

2001 • 305 citations

Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

2001 • 294 citations

TWEAK Induces Angiogenesis and Proliferation of Endothelial Cells

1999 • 240 citations

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

2002 • 213 citations

RelB Cellular Regulation and Transcriptional Activity Are Regulated by p100

2002 • 213 citations

NF-κB Signaling

2002 • 213 citations

Constitutive activation of nuclear factor ?B in hepatocellular carcinoma

2000 • 201 citations

Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I

2001 • 200 citations

The Mitogen-inducible Fn14 Gene Encodes a Type I Transmembrane Protein that Modulates Fibroblast Adhesion and Migration

1999 • 196 citations

The Fn14 Immediate-Early Response Gene Is Induced During Liver Regeneration and Highly Expressed in Both Human and Murine Hepatocellular Carcinomas

2000 • 182 citations

The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation

2003 • 174 citations

Lymphotoxin ॆ Receptor Induces Sequential Activation of Distinct NF-κB Factors via Separate Signaling Pathways

2003 • 171 citations

Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells

2002 • 167 citations

Multiple Pathways of TWEAK-Induced Cell Death

2002 • 164 citations

Involvement of Tweak in Interferon γ–Stimulated Monocyte Cytotoxicity

2000 • 154 citations

TWEAK can induce cell death via endogenous TNF and TNF receptor 1

1999 • 147 citations

The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial Tumors

2003 • 141 citations

Fibroblast Growth Factor-Inducible 14 Mediates Multiple Pathways of TWEAK-Induced Cell Death

2003 • 135 citations

Lymphotoxin and lipopolysaccharide induce NF‐κB‐p52 generation by a co‐translational mechanism

2003 • 127 citations

Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells.

1995 • 126 citations

Heterogeneous chromosomal aberrations generate 3' truncations of the NFKB2/lyt-10 gene in lymphoid malignancies

1994 • 105 citations

Expression of LMP1 in epithelial cells leads to the activation of a select subset of NF-kappa B/Rel family proteins

1995 • 102 citations

Constitutive activation of transcription factor AP-1 in primary adult T-cell leukemia cells.

2000 • 96 citations

Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.

2003 • 91 citations

Molecular analysis of cutaneous B- and T-cell lymphomas

1995 • 82 citations

Differential Expression of the Transcription Factor NF-κB during Human Mononuclear Phagocyte Differentiation to Macrophages and Dendritic Cells

2000 • 80 citations

The Carboxyl-Terminal Region of IκB Kinase γ (IKKγ) Is Required for Full IKK Activation

2002 • 80 citations

Role of Rel/NF‐κB transcription factors in apoptosis of human hepatocellular carcinoma cells

2002 • 78 citations

Lymphotoxin‐β receptor mediates NEMO‐independent NF‐κB activation

2002 • 71 citations

Discrete Signaling Regions in the Lymphotoxin-β Receptor for Tumor Necrosis Factor Receptor-associated Factor Binding, Subcellular Localization, and Activation of Cell Death and NF-κB Pathways

2000 • 59 citations

GM-CSF-induced in vivo expansion of splenic dendritic cells and their strong costimulation activity

1996 • 54 citations

A Novel Secreted Form of Immune Suppressor Factor with High Homology to Vacuolar ATPases Identified by a Forward Genetic Approach of Functional Screening Based on Cell Proliferation

2001 • 10 citations

A recessive mutant cell line with a constitutive IκB kinase activity

2002 • 7 citations