Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

1995 • 1,296 citations

NF-kB: a crucial transcription factor for glial and neuronal cell function

1997 • 1,005 citations

Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB

1999 • 1,001 citations

Requirement for NF-κB in osteoclast and B-cell development

1997 • 994 citations

Osteopetrosis in mice lacking NF-κB1 and NF-κB2

1997 • 988 citations

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors.

1993 • 819 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Transcriptional Cross Talk between NF-κB and p53

1999 • 590 citations

Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons

1999 • 552 citations

Requirement of NF-κB Activation to Suppress p53-Independent Apoptosis Induced by Oncogenic Ras

1997 • 547 citations

Multiple signals converging on NF-κB

1999 • 483 citations

A requirement for NF-kappa B activation in Bcr-Abl-mediated transformation

1998 • 397 citations

Enhancement of radiosensitivity by proteasome inhibition: Implications for a role of NF-κB

2001 • 323 citations

Inhibition of NF-kappa B cellular function via specific targeting of the Ikappa B-ubiquitin ligase

1997 • 238 citations

Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis

1998 • 164 citations

Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation.

2000 • 160 citations

A Critical Role for the RelA Subunit of Nuclear Factor κB in Regulation of Multiple Immune-response Genes and in Fas-induced Cell Death

1999 • 147 citations

Inhibition of Nuclear Factor-κB Activity Is Involved in E1A-mediated Sensitization of Radiation-induced Apoptosis

1997 • 123 citations

Inhibition of NF- B, Clonogenicity, and Radiosensitivity of Human Cancer Cells

1999 • 97 citations

Adenovirus-mediated p53 Gene Therapy for Human Gliomas

1999 • 87 citations

Inhibition of NF-κB Activation in Combination with Bcl-2 Expression Allows for Persistence of First-Generation Adenovirus Vectors in the Mouse Liver

1998 • 77 citations

Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor.

1994 • 64 citations

Adenovirally mediated gene transfer into experimental solid brain tumors and leptomeningeal cancer cells

1995 • 61 citations

Adenovirus-mediated gene transfer to the brain: methodological assessment

1997 • 61 citations

The miti-mere and pdm1 Genes Collaborate during Specification of the RP2/sib Lineage in Drosophila Neurogenesis

1995 • 60 citations

Inhibition of nuclear factor-kappaB activation confers sensitivity to tumor necrosis factor-alpha by impairment of cell cycle progression in human glioma cells.

1999 • 53 citations

The Dual Effect of Adenovirus Type 5 E1A 13S Protein on NF-κB Activation Is Antagonized by E1B 19K

1996 • 50 citations

Characterization of a neuronal κB-binding factor distinct from NF-κB

1999 • 47 citations

Inhibition of IκB-α phosphorylation at serine and tyrosine acts independently on sensitization to DNA damaging agents in human glioma cells

2000 • 37 citations

Tumor Necrosis Factor α Induces the Adenovirus Early 3 Promoter by Activation of NF-κB

1996 • 33 citations

c-Jun Does Not Mediate Hepatocyte Apoptosis Following NFκB Inhibition and Partial Hepatectomy

2000 • 15 citations

A Hydrophobic Region within the Adenovirus E1B 19 kDa Protein Is Necessary for the Transient Inhibition of NF-κB Activated by Different Stimuli

1996 • 12 citations

Adenovirus‐mediated Gene Transduction of IkB or IkB Plus Bax Gene Drastically Enhances Tumor Necrosis Factor (TNF)‐induced Apoptosis in Human Gliomas

2000 • 12 citations