Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

1999 • 2,147 citations

RANK is essential for osteoclast and lymph node development

1999 • 1,417 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

1999 • 978 citations

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

1999 • 827 citations

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1997 • 791 citations

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

1998 • 710 citations

Limb and Skin Abnormalities in Mice Lacking IKKα

1999 • 609 citations

Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice

1999 • 581 citations

Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.

1991 • 576 citations

NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

1998 • 533 citations

Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1998 • 531 citations

NF-κB Activation: The IκB Kinase Revealed?

1997 • 492 citations

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1999 • 475 citations

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase

1999 • 448 citations

Inhibition of TNF-induced apoptosis by NF-κB

1998 • 370 citations

TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

1996 • 343 citations

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

1998 • 294 citations

Targeted disruption ofTraf5gene causes defects in CD40- and CD27-mediated lymphocyte activation

1999 • 185 citations

Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB

1997 • 168 citations

Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia (aly) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase

2000 • 164 citations

Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage

1998 • 161 citations

Lymphotoxin‐α‐deficient and TNF receptor‐I‐deficient mice define developmental and functional characteristics of germinal centers

1997 • 149 citations

Molecular Determinants of NF-κB-Inducing Kinase Action

1998 • 142 citations

Lymphotoxin β Receptor Triggering Induces Activation of the Nuclear Factor κB Transcription Factor in Some Cell Types

1996 • 70 citations

Involvement of distinct cellular compartments in the abnormal lymphoid organogenesis in lymphotoxin-alpha-deficient mice and alymphoplasia (aly) mice defined by the chimeric analysis.

1999 • 61 citations

Discrete Signaling Regions in the Lymphotoxin-β Receptor for Tumor Necrosis Factor Receptor-associated Factor Binding, Subcellular Localization, and Activation of Cell Death and NF-κB Pathways

2000 • 59 citations

Involvement of Distinct Cellular Compartments in the Abnormal Lymphoid Organogenesis in Lymphotoxin-α-Deficient Mice and Alymphoplasia (aly) Mice Defined by the Chimeric Analysis

1999 • 54 citations