Differential expression of Janus kinase 3 (JAK3), matrix metalloproteinase 13 (MMP13), heat shock protein 60 (HSP60), and mouse double minute 2 (MDM2) in human colorectal cancer progression using human cancer cDNA microarrays

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Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

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Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters

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Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.

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Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck.

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Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference.

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Jak family of kinases in cancer.

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Collagenase-3 (MMP-13) is Expressed by Tumor Cells in Invasive Vulvar Squamous Cell Carcinomas

1999 • 133 citations

Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma

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Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: overexpression of oncogene MET correlates with tumor differentiation in ESCC.

2001 • 123 citations

Neuregulin-1 Activates the JAK-STAT Pathway and Regulates Lung Epithelial Cell Proliferation

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Identification of Novel Cellular Targets in Biliary Tract Cancers Using Global Gene Expression Technology

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Matrix metalloproteinase 13 activity is associated with poor prognosis in colorectal cancer

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Selective regulation ofBcl-X_Lby a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

1998 • 110 citations

Analysis of polypeptide expression in benign and malignant human breast lesions

1997 • 109 citations

p53 alterations are associated with improved prognosis in distal colonic carcinomas.

1997 • 107 citations

The Kinase Domain of Jak2 Mediates Induction of Bcl-2 and Delays Cell Death in Hematopoietic Cells

1997 • 107 citations

60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis

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Identification of tumor markers in models of human colorectal cancer using a 19,200-element complementary DNA microarray.

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Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways

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Analysis of heat‐shock protein expression in myeloid leukaemia cells by flow cytometry

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Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain

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Aberrant expression of interleukin-7 (IL-7) and its signalling complex in human breast cancer

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Expression of Janus Kinase 3 in Human Endothelial and Other Non-lymphoid and Non-myeloid Cells

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Gene Expression Profiling in Lymph Node-Positive and Lymph Node-Negative Colorectal Cancer

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Mdm2 Gene Amplification in Gastric Cancer Correlation with Expression of Mdm2 Protein and p53 Alterations

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Simultaneous determination of matrix metalloproteinase (MMP)-7, MMP-1, -3, and -13 gene expression by multiplex PCR in colorectal carcinomas

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Inactivation of the PTEN gene protein product is associated with the invasiveness and metastasis, but not angiogenesis, of breast cancer

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Characterization of colonic polyps by two-dimensional gel electrophoresis

1999 • 39 citations

MDM2/p53 protein expression in the development of colorectal adenocarcinoma,

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cDNA microarray analysis of gene expression in pathologic stage IA nonsmall cell lung carcinomas

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Assessment of Differential Gene Expression Patterns in Human Colon Cancers

2000 • 33 citations

Expression profiling and interferon-beta regulation of liver metastases in colorectal cancer cells.

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Ras and Signal Transducer and Activator of Transcription (STAT) Are Essential and Sufficient Downstream Components of Janus Kinases in Cell Proliferation

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