Characterization of colonic polyps by two-dimensional gel electrophoresis

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Is a p53-Regulated Inhibitor of G2/M Progression

1997 • 1,238 citations

Cell Biology: a Laboratory Handbook

1995 • 1,226 citations

A Laboratory handbook

1989 • 418 citations

Improved and simplified in‐gel sample application using reswelling of dry immobilized pH gradients

1997 • 309 citations

Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells.

1993 • 256 citations

Identification of mouse liver proteins on two‐dimensional electrophoresis gels by matrix‐assisted laser desorption/ionization mass spectrometry ofin situenzymatic digests

1997 • 231 citations

Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation.

1997 • 205 citations

The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas

1993 • 195 citations

Aberrant crypts in human colonic mucosa: Putative preneoplastic lesions

1992 • 183 citations

Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity

1997 • 177 citations

Rho proteins play a critical role in cell migration during the early phase of mucosal restitution.

1997 • 163 citations

Rapid onset of apoptosis in vitro follows disruption of beta 1- integrin/matrix interactions in human colonic crypt cells

1996 • 162 citations

EXPRESSION OF NUCLEOPHOSMIN/B23 IN NORMAL AND NEOPLASTIC COLORECTAL MUCOSA

1996 • 152 citations

Identification of numatrin, the nuclear matrix protein associated with induction of mitogenesis, as the nucleolar protein B23. Implication for the role of the nucleolus in early transduction of mitogenic signals.

1988 • 151 citations

Translocation of nucleolar phosphoprotein B23 () induced by selective inhibitors of ribosome synthesis

1985 • 148 citations

A method for the isolation and culture of human colonic crypts in collagen gels

1987 • 122 citations

Short-chain fatty acids promote the migration of colonic epithelial cells in vitro

1997 • 96 citations

Molecular cloning and characterization of yeast rho GDP dissociation inhibitor.

1994 • 86 citations

Nuclear matrix proteins in human coloncancer.

1994 • 79 citations

Inward growth of colonic adenomatous polyps

1996 • 78 citations

Stratifin, a keratinocyte specific 14-3-3 protein, harbors a pleckstrin homology (ph) domain and enhances protein kinase c activity

1995 • 68 citations

Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques

1985 • 65 citations

Two‐dimensional electrophoretic analysis of proteins expressed by normal and cancerous human crypts: Application of mass spectrometry to peptide‐mass fingerprinting

1994 • 65 citations

Aberrant crypt foci in patients with colorectal cancer

1998 • 63 citations

n‐3 fatty acids decrease colonic epithelial cell proliferation in high‐risk bowel mucosa

1996 • 63 citations

A qualitative and quantitative protein database approach identifies individual and groups of functionally related proteins that are differentially regulated in simian virus 40 (SV40) transformed human keratinocytes: An overview of the functional changes associated with the transformed phenotype

1994 • 63 citations

Two-dimensional electrophoresis with immobilized pH gradients: current state

1993 • 59 citations

Peptide sequence information derived by partial acid hydrolysis and matrix-assisted laser desorption/ionization mass spectrometry

1994 • 57 citations

Effects of fatty acids on expression of genes encoding subunits of cytochrome c oxidase and cytochrome c oxidase activity in HT29 human colonic adenocarcinoma cells.

1991 • 56 citations

Differential Hsp70 plasma-membrane expression on primary human tumors and metastases in mice with severe combined immunodeficiency

1998 • 56 citations

A two‐dimensional gel database of human colon carcinoma proteins

1997 • 53 citations

Standardized characterization of gene expression in human colorectal epithelium by two‐dimensional electrophoresis

1997 • 53 citations

APC mutation and the crypt cycle in murine and human intestine.

1997 • 51 citations

Abnormalities of epithelial apoptosis in multistep colorectal neoplasia demonstrated by terminal deoxyuridine nick end labeling

1996 • 47 citations

Expansion of the epithelial cell proliferative compartment and frequency of adenomatous polyps in the colon correlate with the strength of family history of colorectal cancer.

1993 • 34 citations

Changes in the size and docosahexaenoic acid content of adipocytes during chick embryo development

1996 • 33 citations

Nonreducing two‐dimensional polyacrylamide gel electrophoretic analysis of human colonic proteins

1995 • 27 citations

Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas.

1993 • 26 citations

The different expression of proteins recognized by monoclonal anti‐heat shock protein 70 (hsp70) antibody in human colonic diseases

1997 • 25 citations

Changes in keratin expression during fetal and postnatal development of intestinal epithelial cells

1992 • 22 citations

Rho small G protein and cytoskeletal control.

1994 • 20 citations

A simplified silver diammine method for the staining of nucleic acids in polyacrylamide gels

1996 • 18 citations

Differentiation inducing effects of butyrate and DMSO on human intestinal tumor cell lines in culture.

1985 • 12 citations

Effect of TGF‐β on differentiated organoids of the colon carcinoma cell line LIM 1863

1995 • 12 citations

Hsp60/chaperonin gene expression and differentiation of human colon adenocarcinoma and multipotent leukaemic cells

1992 • 11 citations

A colonic tissue architecture assay applied to human colon carcinoma cells

1997 • 9 citations

Molecular Characterization of Cellular Proteins from Colorectal Tumors

1996 • 9 citations

Comparison of Nuclear Matrix Protein Composition in Colon Cancer and Dysplasia

1998 • 8 citations

[Colorectal cancer mortality can be reduced. Fecal blood screening is an efficient test].

1998 • 3 citations