Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 • 699 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Structure and expression of the human cystatin C gene

1990 • 605 citations

The Matrix Metalloproteinases and Their Inhibitors

1992 • 604 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization.

1986 • 515 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.

1993 • 479 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

[2] Production of antisera with small doses of immunogen: multiple intradermal injections

1981 • 442 citations

Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.

1990 • 406 citations

The collagen substrate specificity of human skin fibroblast collagenase.

1981 • 371 citations

The collagenase gene family in humans consists of at least four members

1988 • 364 citations

Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.

1987 • 323 citations

Extracellular vaccinia virus formation and cell-to-cell virus transmission are prevented by deletion of the gene encoding the 37,000-Dalton outer envelope protein

1991 • 302 citations

The collagen substrate specificity of human neutrophil collagenase.

1987 • 285 citations

Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells.

1990 • 249 citations

Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members

1989 • 212 citations

Cathepsin B and cystatins: evidence for a role in cancer progression.

1990 • 206 citations

Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase.

1992 • 197 citations

The origin of matrix metalloproteinases and their familial relationships

1991 • 182 citations

Characterization of the procollagen IV cleavage products produced by a specific tumor collagenase.

1984 • 178 citations

Structure-function relationships in the collagenase family member transin.

1988 • 169 citations

Substrate specificities and activation mechanisms of matrix metalloproteinases

1991 • 164 citations

Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family.

1994 • 162 citations

Synthetic substrates for vertebrate collagenase

1977 • 142 citations

The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase

1993 • 132 citations

Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity.

1993 • 128 citations

Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: a review

1993 • 123 citations

Cloning and sequencing of mouse collagenase cDNA Divergence of mouse and rat collagenases from the other mammalian collagenases

1992 • 120 citations

Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues.

1989 • 119 citations

Role of zinc-binding- and hemopexin domain-encoded sequences in the substrate specificity of collagenase and stromelysin-2 as revealed by chimeric proteins.

1993 • 109 citations

Parathyroid hormone induces transcription of collagenase in rat osteoblastic cells by a mechanism using cyclic adenosine 3',5'-monophosphate and requiring protein synthesis.

1992 • 95 citations

Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells.

1992 • 92 citations

Identification of the major protein components in breast secretions from women with benign and malignant breast diseases.

1992 • 87 citations

Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor.

1991 • 85 citations

Isolation and characterization of a pepsin C zymogen produced by human breast tissues.

1992 • 42 citations

Expression of pepsinogen C in human breast tumours and correlation with clinicopathologic parameters

1993 • 36 citations

Assignment of the human stromelysin 3 (STMY3) gene to the q11.2 region of chromosome 22

1992 • 32 citations

A new technique for differential and simultaneous staining of nerve cells and fibers

1985 • 31 citations

Preparation of active recombinant TIMP-1 from Escherichia coli inclusion bodies and complex formation with the recombinant catalytic domain of PMNL-collagenase

1993 • 30 citations

Cathepsin D in breast secretions from women with breast cancer

1993 • 18 citations

Characterization of multiple cathepsin B mRNAs in murine B16a melanoma.

1991 • 9 citations