Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Epidermal growth factor.

1990 • 1,645 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Light and electron immunocytochemical localization of AMPA‐selective glutamate receptors in the rat brain

1992 • 988 citations

Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1989 • 978 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

A 38,000-dalton membrane protein (p38) present in synaptic vesicles.

1985 • 856 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling

1989 • 784 citations

Comparison of Two Forms of Long-Term Potentiation in Single Hippocampal Neurons

1990 • 755 citations

Amino acid neurotransmitters and their pathways in the mammalian central nervous system

1983 • 646 citations

Binding of SH2 Domains of Phospholipase Cγ1, GAP, and Src to Activated Growth Factor Receptors

1990 • 608 citations

AMPA glutamate receptor subunits are differentially distributed in rat brain

1993 • 574 citations

Identification of intracellular receptor proteins for activated protein kinase C.

1991 • 505 citations

Binding of Transforming Protein, P47 ^gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

1990 • 433 citations

Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.

1989 • 402 citations

Antiphosphotyrosine Recovery of Phospholipase C Activity After EGF Treatment of A-431 Cells

1988 • 324 citations

Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I

1990 • 315 citations

The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma.

1990 • 314 citations

Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by d(−)aminophosphonovalerate

1987 • 269 citations

A protein kinase C isozyme is translocated to cytoskeletal elements on activation.

1990 • 257 citations

Inositol phospholipid-specific phospholipase C: interaction of the γ isoform with tyrosine kinase

1991 • 233 citations

Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzyme

1991 • 212 citations

Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas.

1991 • 207 citations

The characterization and localization of the glutamate receptor subunit GluR1 in the rat brain

1991 • 189 citations

Tyrosine residues in bovine phospholipase C-gamma phosphorylated by the epidermal growth factor receptor in vitro.

1990 • 178 citations

Domain structure and phosphorylation of protein kinase C.

1987 • 168 citations

Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7

1993 • 155 citations

Stimulation of Phospholipase C-γ1 Membrane Association by Epidermal Growth Factor

1990 • 153 citations

Effects of excitatory amino acid antagonists on evoked and spontaneous excitatory potentials in guinea‐pig hippocampus.

1986 • 147 citations

Quantitative localization of AMPA/kainate and kainate glutamate receptor subunit immunoreactivity in neurochemically identified subpopulations of neurons in the prefrontal cortex of the macaque monkey

1993 • 146 citations

Identification of two epidermal growth factor-sensitive tyrosine phosphorylation sites of phospholipase C-gamma in intact HSC-1 cells.

1990 • 136 citations

Differential expression of the p65 gene family

1991 • 126 citations

p65 Fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C

1992 • 105 citations

Commissural synapses, but not mossy fiber synapses, in hippocampal field CA3 exhibit associative long-term potentiation and depression

1989 • 92 citations

Parvalbumin‐ and calbindin D_28K‐immunoreactive neurons in the hippocampal formation of the macaque monkey

1991 • 92 citations

Morphological variability and developmental aspects of monkey and human granule cells: differences between the rodent and primate dentate gyrus.

1992 • 86 citations

Separate mechanisms of long-term potentiation in two input systems to CA3 pyramidal neurons of rat hippocampal slices as revealed by the whole-cell patch-clamp technique

1991 • 72 citations

Immunological Detection of the NMDAR1 Glutamate Receptor Subunit Expressed in Human Embryonic Kidney 293 Cells and in Rat Brain

1992 • 71 citations

Target cell specificity of synaptic connections in the hippocampus

1991 • 68 citations

Effects of social deprivation in prepubescent rhesus monkeys: immunohistochemical analysis of the neurofilament protein triplet in the hippocampal formation

1993 • 66 citations

Inhibition of protein kinase C function by injection of intracellular receptors for the enzyme

1992 • 55 citations

Organization and quantitative analysis of kainate receptor subunit GluR5-7 immunoreactivity in monkey hippocampus

1993 • 51 citations

Selective phospholipase C activation

1991 • 49 citations

Epidermal growth factor and platelet‐derived growth factor promote translocation of phospholipase C‐γ from cytosol to membrane

1990 • 34 citations

A novel photoaffinity ligand for the phencyclidine site of the N-methyl-D-aspartate receptor labels a Mr 120,000 polypeptide.

1990 • 27 citations

Similarity between phospholipase C and the regulatory domain of protein kinase C

1989 • 15 citations