EM Visualization of Transcription by RNA Polymerase II

Visualization of Single RNA Transcripts in Situ

1998 • 1,374 citations

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1997 • 905 citations

Visualization of Nucleolar Genes

1969 • 865 citations

Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase

1996 • 645 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II.

1988 • 370 citations

RNA polymerase II is an essential mRNA polyadenylation factor

1998 • 358 citations

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

1996 • 351 citations

Functional association between promoter structure and transcript alternative splicing

1997 • 340 citations

How RNA polymerase II terminates transcription in higher eukaryotes

1989 • 301 citations

Transcription factor TFIID recruits factor CPSF for formation of 3′ end of mRNA

1997 • 301 citations

Definition of an efficient synthetic poly(A) site.

1989 • 285 citations

Three Functional Classes of Transcriptional Activation Domains

1996 • 267 citations

Coupling Termination of Transcription to Messenger RNA Maturation in Yeast

1998 • 264 citations

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.

1987 • 247 citations

Transcriptional elongation by RNA polymerase II is stimulated by transactivators

1994 • 243 citations

Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3′ end processing in the human alpha 2 globin gene.

1986 • 236 citations

Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns.

1991 • 200 citations

Cell Death Mediators in Autoimmune Diabetes—No Shortage of Suspects

1997 • 177 citations

Pre-mRNA Processing and the CTD of RNA Polymerase II: The Tail That Wags the Dog?

1997 • 165 citations

The addition of 5′ cap structures occurs early in hnRNA synthesis and prematurely terminated molecules are capped

1980 • 161 citations

A CTD function linking transcription to splicing

1997 • 160 citations

Terminal Exon Definition Occurs Cotranscriptionally and Promotes Termination of RNA Polymerase II

1999 • 156 citations

A Functional Interaction between the Carboxy-Terminal Domain of RNA Polymerase II and Pre-mRNA Splicing

1997 • 139 citations

MAZ-dependent termination between closely spaced human complement genes.

1994 • 117 citations

Promoter-proximal pausing by RNA polymerase II in vitro: transcripts shorter than 20 nucleotides are not capped.

1983 • 112 citations

Transcription units as RNA processing units

1997 • 110 citations

A pause site for RNA polymerase II is associated with termination of transcription.

1991 • 110 citations

Structure of tbe gene forXenopustranscription factor TMIIIA

1986 • 108 citations

Upstream introns influence the efficiency of final intron removal and RNA 3'-end formation.

1994 • 101 citations

Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.

1993 • 100 citations

Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes of Saccharomyces cerevisiae

1998 • 99 citations

Transcriptional termination in the Balbiani ring 1 gene is closely coupled to 3′-end formation and excision of the 3′-terminal intron

1998 • 87 citations

3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes.

1993 • 71 citations

RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence.

1989 • 70 citations

A nuclear micrococcal-sensitive, ATP-dependent exoribonuclease degrades uncapped but not capped RNA substratesx

1991 • 70 citations

Distinct activated and non-activated RNA polymerase II complexes in yeast.

1996 • 61 citations

Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II

1997 • 42 citations

Role of RNA Polymerase II Carboxy-terminal Domain in Coordinating Transcription with RNA Processing

1998 • 41 citations

Distinct Properties of c-myc Transcriptional Elongation Are Revealed in Xenopus Oocytes and Mammalian Cells and by Template Titration, 5,6-Dichloro-1-β-D-Ribofuranosylbenzimidazole (DRB), and Promoter Mutagenesis

1993 • 27 citations

Premature Termination of Transcription Can Be Induced on an Injected α-Tubulin Gene in Xenopus Oocytes

1990 • 23 citations

Transcription elongation in the human c-myc gene is governed by overall transcription initiation levels in Xenopus oocytes.

1993 • 11 citations

Distinct properties of c-myc transcriptional elongation are revealed in Xenopus oocytes and mammalian cells and by template titration, 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB), and promoter mutagenesis.

1993 • 10 citations

Premature termination of transcription can be induced on an injected alpha-tubulin gene in Xenopus oocytes.

1990 • 9 citations

Chapter 21 EM Visualization of Transcriptionally Active Genes after Injection into Xenopus Oocyte Nuclei

1997 • 8 citations

Stimulation of RNA 3′ processing by flanking DNA in Xenopus oocytes

1998 • 1 citations

Pre-mRNA Processing and the Minireview CTD of RNA Polymerase II: The Tail That Wags the Dog?

1997 • 1 citations