Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3′ end processing in the human alpha 2 globin gene.

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

1979 • 532 citations

The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

1980 • 531 citations

Nucleotide sequences in Xenopus 5S DNA required for transcription termination

1981 • 515 citations

α-Thalassaemia caused by a polyadenylation signal mutation

1983 • 407 citations

The primary transcription unit of the mouse β-Major globin gene

1981 • 358 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAA

1983 • 278 citations

Transcriptional Regulation of Hemoglobin Switching in Chicken Embryos

1981 • 265 citations

Requirement of a downstream sequence for generation of a poly(A) addition site

1984 • 261 citations

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

1984 • 251 citations

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: Mapping of nascent RNA molecular labeled in isolated nuclei

1977 • 198 citations

Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene.

1985 • 195 citations

Transcription of mouse rDNA terminates downstream of the 3′ end of 28S RNA and involves interaction of factors with repeated sequences in the 3′ spacer

1985 • 189 citations

Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids.

1983 • 164 citations

Transcriptional Regulation of Globin Gene Expression in the Human Erythroid Cell Line K562

1983 • 149 citations

Globin RNA transcription: A possible termination site and demonstration of transcriptional control correlated with altered chromatin structure

1982 • 144 citations

3' editing of mRNAs: sequence requirements and involvement of a 60-nucleotide RNA in maturation of histone mRNA precursors.

1984 • 142 citations

The major late adenovirus type-2 transcription unit: Termination is downstream from the last poly(A) site

1979 • 141 citations

Simian virus 40 enhancer increases number of RNA polymerase II molecules on linked DNA

1985 • 138 citations

Termination of transcription in the mouse α-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site

1984 • 131 citations

Formation of the 3′ end of histone mRNA by post-transcriptional processing

1984 • 129 citations

Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse β-major globin terminator element

1985 • 109 citations

Molecular evolution of the human adult alpha-globin-like gene region: insertion and deletion of Alu family repeats and non-Alu DNA sequences.

1983 • 100 citations

Transcription termination occurs within a 1000 base pair region downstream from the poly(A) site of the mouse β-globin (major) gene

1984 • 98 citations

Gene expression in murine erythroleukemia cells

1984 • 78 citations

Termination of the ovalbumin gene transcription.

1984 • 63 citations

The 3′ end of Drosophila histone H3 mRNA is produced by a processing activity in vitro

1984 • 60 citations

Transcription unit of the rabbit beta 1 globin gene.

1985 • 48 citations

Transcriptional analysis of human zeta globin genes.

1984 • 34 citations

Transcriptional activity of the human psendogene Φα globin compared with α globin, its functional gene counterpart

1983 • 28 citations

Transcription Unit of the Rabbit β1 Globin Gene

1985 • 19 citations

Molecular biology: Globin gene monkey business

1986 • 10 citations