Distinct Properties of c-myc Transcriptional Elongation Are Revealed in Xenopus Oocytes and Mammalian Cells and by Template Titration, 5,6-Dichloro-1-β-D-Ribofuranosylbenzimidazole (DRB), and Promoter Mutagenesis

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged

1988 • 662 citations

Control of c-myc Regulation in Normal and Neoplastic Cells

1991 • 632 citations

Differential Expression of the Translocated and the Untranslocated c- myc Oncogene in Burkitt Lymphoma

1983 • 328 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

New light on Myc and Myb. Part I. Myc.

1990 • 325 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II

1989 • 304 citations

Control of formation of two distinct classes of RNA polymerase II elongation complexes.

1992 • 295 citations

HIV-1 Tat protein promotes formation of more-processive elongation complexes.

1991 • 295 citations

MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination.

1992 • 291 citations

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.

1989 • 283 citations

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.

1992 • 280 citations

The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region.

1992 • 266 citations

Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter.

1989 • 262 citations

Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression

1986 • 254 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole inhibits transcription elongation by RNA polymerase II in vitro

1989 • 225 citations

Elongation factor-dependent transcript shortening by template-engaged RNA polymerase II.

1992 • 197 citations

HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.

1992 • 195 citations

Transcription Elongation Factor SII (TFIIS) Enables RNA Polymerase II to Elongate through a Block to Transcription in a Human Gene in Vitro

1989 • 189 citations

DNA sequence requirements for generating paused polymerase at the start of hsp70.

1992 • 188 citations

Hold back of RNA polymerase II at the transcription start site mediates down-regulation of c-myc in vivo.

1992 • 182 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains.

1987 • 160 citations

Promoter melting and TFIID complexes on Drosophila genes in vivo.

1992 • 155 citations

Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II.

1991 • 152 citations

Transcription attenuation.

1988 • 128 citations

Multiple mechanisms regulate c-myc gene expression during normal T cell activation.

1988 • 124 citations

RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene.

1991 • 124 citations

RAP30/74: a general initiation factor that binds to RNA polymerase II.

1988 • 115 citations

The c-myc gene encodes superimposed RNA polymerase II and III promoters

1987 • 99 citations

Transcriptional and post-transcriptional regulation of c-mye expression during the differentiation of murine erythroleukemia Friend cells

1986 • 97 citations

The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles.

1990 • 96 citations

DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc.

1989 • 87 citations

Intrinsic sites of transcription termination and pausing in the c-myc gene.

1988 • 85 citations

Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?

1991 • 77 citations

Molecular requirements for transcriptional initiation of the murine c-myc gene.

1989 • 77 citations

Purified elongation factor SII is sufficient to promote read-through by purified RNA polymerase II at specific termination sites in the human histone H3.3 gene.

1990 • 75 citations

Properties of a Drosophila RNA Polymerase II Elongation Factor

1989 • 73 citations

A cis-acting element in the promoter region of the murine c-myc gene is necessary for transcriptional block.

1989 • 70 citations

Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter

1992 • 65 citations

Role of the Mammalian Transcription Factors IIF, IIS, and IIX during Elongation by RNA Polymerase II

1991 • 63 citations

Stability of Drosophila RNA Polymerase II Elongation Complexes In Vitro

1992 • 62 citations

Distinct modes of transcription read through or terminate at the c-myc attenuator.

1992 • 48 citations

Accurate, TATA box-dependent polymerase III transcription from promoters of the c-myc gene in injected Xenopus oocytes.

1989 • 47 citations

RNA Polymerase II Pauses at the 5′ End of the Transcriptionally Induced Drosophila hsp70 Gene

1991 • 47 citations

Transcription of c-myc in human mononuclear cells is regulated by an elongation block.

1987 • 38 citations

Premature termination of transcription from the P1 promoter of the mouse c-myc gene.

1991 • 37 citations

Sequences in the Human c-myc P2 Promoter Affect the Elongation and Premature Termination of Transcripts Initiated from the Upstream P1 Promoter

1992 • 34 citations

5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription of the beta-hemoglobin gene in vivo at initiation.

1987 • 33 citations

Analysis of Premature Termination in c-myc during Transcription by RNA Polymerase II in a HeLa Nuclear Extract

1991 • 32 citations

A protein-binding site in the c-myc promoter functions as a terminator of RNA polymerase II transcription.

1992 • 28 citations

Premature Termination of Transcription Can Be Induced on an Injected α-Tubulin Gene in Xenopus Oocytes

1990 • 23 citations

Mapping of RNA polymerase on mammalian genes in cells and nuclei.

1992 • 23 citations

Effects of IL-3 on promoter usage, attenuation and antisense transcription of the c-myc oncogene in the IL-3-dependent Ba/F3 early pre-B cell line.

1991 • 23 citations

Identification and purification of a yeast protein that affects elongation by RNA polymerase II

1991 • 23 citations

The Block to Transcription Elongation at the Minute Virus of Mice Attenuator Is Regulated by Cellular Elongation Factors

1991 • 19 citations

A heat-labile factor promotes premature 3' end formation in exon 1 of the murine adenosine deaminase gene in a cell-free transcription system.

1991 • 18 citations

Transcription elongation in the human c-myc gene is governed by overall transcription initiation levels in Xenopus oocytes.

1993 • 11 citations

Transcriptional control of c-myc gene expression during stimulation of murine B lymphocytes.

1990 • 5 citations

Deleted Work

1955 • 0 citations