Stimulation of RNA 3′ processing by flanking DNA in Xenopus oocytes

Mechanism and regulation of mRNA polyadenylation

1997 • 762 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Point mutations in AAUAAA and the poly (A) addition site: effects on the accuracy and efficiency of cleavage and polyadenylationin vitro

1990 • 498 citations

α-Thalassaemia caused by a polyadenylation signal mutation

1983 • 407 citations

How RNA polymerase II terminates transcription in higher eukaryotes

1989 • 301 citations

MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination.

1992 • 291 citations

Definition of an efficient synthetic poly(A) site.

1989 • 285 citations

Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit β-globin mRNA 3′ end formation

1987 • 229 citations

Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene.

1985 • 195 citations

Pre-mRNA Processing and the CTD of RNA Polymerase II: The Tail That Wags the Dog?

1997 • 165 citations

3′-End cleavage and polyadenylation of mRNA precursors

1995 • 136 citations

Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site.

1995 • 117 citations

A pause site for RNA polymerase II is associated with termination of transcription.

1991 • 110 citations

Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?

1991 • 77 citations

An Intron Enhancer Containing a 5′ Splice Site Sequence in the Human Calcitonin/Calcitonin Gene-Related Peptide Gene

1995 • 74 citations

Transcription and polyadenylation in a short human intergenic region

1997 • 37 citations

Premature Termination of Transcription Can Be Induced on an Injected α-Tubulin Gene in Xenopus Oocytes

1990 • 23 citations

Alternative 3' processing ofXenopusα-tubulin mRNAs; efficient use of a CAUAAA polyadenylation signal

1992 • 19 citations

An oocyte-expressed α-Dublin gene inXenopus laevis, sequences required for the initiation of transcription

1989 • 12 citations

Premature termination of tubulin gene transcription in Xenopus oocytes is due to promoter-dependent disruption of elongation.

1993 • 12 citations

Premature termination of transcription can be induced on an injected alpha-tubulin gene in Xenopus oocytes.

1990 • 9 citations