The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression

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Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

NADPH Oxidase: An Update

1999 • 2,134 citations

Cell transformation by the superoxide-generating oxidase Mox1

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Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure

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Xanthine oxidase as a source of free radical damage in myocardial ischemia

1985 • 678 citations

p38 Mitogen-activated Protein Kinase Is a Critical Component of the Redox-sensitive Signaling Pathways Activated by Angiotensin II

1998 • 657 citations

Superoxide Production in Vascular Smooth Muscle Contributes to Oxidative Stress and Impaired Relaxation in Atherosclerosis

1998 • 631 citations

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

2000 • 596 citations

p22phox mRNA Expression and NADPH Oxidase Activity Are Increased in Aortas From Hypertensive Rats

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PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH.

1986 • 489 citations

The p47phox mouse knock-out model of chronic granulomatous disease.

1995 • 487 citations

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2000 • 469 citations

Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries

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Expression of phagocyte NADPH oxidase components in human endothelial cells

1996 • 432 citations

Thrombin Activates the Hypoxia-Inducible Factor-1 Signaling Pathway in Vascular Smooth Muscle Cells

2001 • 415 citations

Novel homologs of gp91phox

2000 • 356 citations

Stimulation of a Vascular Smooth Muscle Cell NAD(P)H Oxidase by Thrombin

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Appearance of superoxide anion radical in cerebral extracellular space during increased prostaglandin synthesis in cats.

1985 • 296 citations

Role of NAD(P)H Oxidase in Angiotensin II–Induced JAK/STAT Signaling and Cytokine Induction

2000 • 273 citations

Platelet-Derived Growth Factor–Stimulated Superoxide Anion Production Modulates Activation of Transcription Factor NF-κB and Expression of Monocyte Chemoattractant Protein 1 in Human Aortic Smooth Muscle Cells

1997 • 257 citations

Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species

1994 • 235 citations

Differential Activation of Mitogen-Activated Protein Kinases in Smooth Muscle Cells by Angiotensin II

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Redox control of vascular smooth muscle proliferation

1998 • 200 citations

Expression of a functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells

1998 • 188 citations

Vascular Effects Following Homozygous Disruption of p47 ^phox

2000 • 158 citations

NADPH Oxidase Activity Is Independent of p47

1996 • 154 citations

Activation of p47 , a Cytosolic Subunit of the Leukocyte NADPH Oxidase

1998 • 141 citations

Identification of a Functional Leukocyte-Type NADPH Oxidase in Human Endothelial Cells : A Potential Atherogenic Source of Reactive Oxygen Species

1999 • 138 citations

Genetic Demonstration of p47phox-Dependent Superoxide Anion Production in Murine Vascular Smooth Muscle Cells

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Mechanism of the Tumor Necrosis Factor α-mediated Induction of Endothelial Tissue Factor

1995 • 125 citations

Role of Increased Production of Superoxide Anions by NAD(P)H Oxidase and Xanthine Oxidase in Prolonged Endotoxemia

1999 • 125 citations

Angiotensin II Type 1 Receptor–Mediated Peroxide Production in Human Macrophages

1999 • 120 citations

Oxidative stress and expression of p22phox are involved in the up‐regulation of tissue factor in vascular smooth muscle cells in response to activated platelets

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Superoxide generation by lipoxygenase in the presence of NADH and NADPH

1994 • 102 citations

Glucocorticoids Inhibit Superoxide Anion Production and p22 Phox mRNA Expression in Human Aortic Smooth Muscle Cells

1998 • 89 citations

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1997 • 80 citations

Thrombin-induced MCP-1 Expression Involves Activation of the p22phox-containing NADPH Oxidase in Human Vascular Smooth Muscle Cells

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Oxidative stress and expression of p22phox are involved in the up-regulation of tissue factor in vascular smooth muscle cells in response to activated platelets

2000 • 48 citations

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1998 • 22 citations