Superoxide generation by lipoxygenase in the presence of NADH and NADPH

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH.

1986 • 489 citations

Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenase-1

1975 • 300 citations

Studies on Cytochrome c Peroxidase

1965 • 276 citations

One-electron reactions in biochemical systems as studied by pulse radiolysis. IV. Oxidation of dihydronicotinamide-adenine dinucleotide

1971 • 153 citations

Lipoxygenase‐mediated production of superoxide anion in senescing plant tissue

1984 • 149 citations

Analysis and computer simulation of aerobic oxidation of reduced nicotinamide adenine dinucleotide catalyzed by horseradish peroxidase

1977 • 143 citations

Lipid Peroxyl Radical Intermediates in the Peroxidation of Polyunsaturated Fatty Acids by Lipoxygenase

1989 • 136 citations

Singlet oxygen production by soybean lipoxygenase isozymes.

1986 • 132 citations

Reaction of peroxidase with reduced nicotinamide-adenine dinucleotide and reduced nicotinamide-adenine dinucleotide phosphate

1965 • 129 citations

Isolation and identification of α-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts formed by the decomposition of the hydroperoxides of linoleic acid, linolenic acid, and arachidonic acid by soybean lipoxygenase

1991 • 75 citations

Superoxide and peroxyl radical generation from the reduction of polyunsaturated fatty acid hydroperoxides by soybean lipoxygenase

1991 • 73 citations

Hydroperoxidase activity of lipoxygenase: Hydrogen peroxide-dependent oxidation of xenobiotics

1988 • 55 citations

A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system

1986 • 54 citations

A unique function for ascorbate

1991 • 48 citations

Stimulation of 5-lipoxygenase activity under conditions which promote lipid peroxidation

1989 • 47 citations

Hydrogen peroxide: A potent activator of dioxygenase activity of soybean lipoxygenase

1990 • 39 citations

Alkyl free radicals from the β-scission of fatty acid alkoxyl radicals as detected by spin trapping in a lipoxygenase system

1990 • 35 citations

Superoxide-dependent and superoxide-independent pathways for reduction of nitroblue tetrazolium in isolated rat cardiac myocytes

1990 • 32 citations

Lipoxygenases and hydroperoxy/hydroxy-eicosatetraenoic acid formation

1987 • 31 citations

Role of lipoxygenase in xenobiotic oxidation: Parathion metabolism catalyzed by highly purified soybean lipoxygenase

1991 • 23 citations

Lipoxygenase: a new pathway for 2-aminofluorene bioactivation

1991 • 23 citations

The formation of free radicals during the reaction of soy bean lipoxidase

1963 • 22 citations

Aldrin epoxidation. Catalytic potential of lipoxygenase coupled with linoleic acid oxidation.

1991 • 20 citations

NADPH-dependent formation of 15- and 12-hydroxyeicosatrienoic acid from arachidonic acid by rat epidermal microsomes.

1991 • 18 citations

Optimization of cofactors which regulate RBL-1 arachidonate 5-lipoxygenase

1989 • 15 citations

Interactions between arachidonic and eicosapentaenoic acids during their dioxygenase-dependent peroxidation

1993 • 11 citations

Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase

1992 • 10 citations