The biogenesis and properties of the parasitophorous vacuoles that harbour Leishmania in murine macrophages

Lack of Acidification inMycobacteriumPhagosomes Produced by Exclusion of the Vesicular Proton-ATPase

1994 • 1,289 citations

The Regulation of Immunity to Leishmania Major

1995 • 1,265 citations

THE ROLE OF pH AND TEMPERATURE IN THE DEVELOPMENT OF LEISHMANIA PARASITES

1994 • 367 citations

The Interaction of Leishmania Species with Macrophages

1992 • 323 citations

Intracellular infection by Leishmania donovani inhibits macrophage apoptosis.

1994 • 299 citations

Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan

1997 • 281 citations

Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH

1990 • 234 citations

Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles

1997 • 234 citations

Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.

1994 • 232 citations

Metacyclogenesis in Leishmania promastigotes

1989 • 215 citations

Vacuoles Induced by Helicobacter pylori Toxin Contain Both Late Endosomal and Lysosomal Markers

1997 • 189 citations

The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway

1996 • 175 citations

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

1992 • 168 citations

Intracellular Leishmania amazonensis amastigotes internalize and degrade MHC class II molecules of their host cells

1995 • 149 citations

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

1997 • 127 citations

Leishmania major interferes with antigen presentation by infected macrophages.

1993 • 124 citations

Deficient expression of co‐stimulatory molecules on Leishmania‐infected macrophages

1994 • 123 citations

Antigen presentation capacity of murine macrophages infected with Leishmania amazonensis amastigotes.

1993 • 102 citations

Processing and Presentation of Endocytically Acquired Protein Antigens by MHC Class II and Class I Molecules

1996 • 99 citations

Macrophage‐T cell interaction in experimental visceral leishmaniasis: failure to express costimulatory molecules on Leishmania‐infected macrophages and its implication in the suppression of cell‐mediated immunity

1995 • 95 citations

Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation

1994 • 86 citations

Exploitation of the complement system by Leishmania promastigotes

1996 • 83 citations

Localization of major histocompatibility complex class II molecules in phagolysosomes of murine macrophages infected with Leishmania amazonensis

1991 • 79 citations

Leishmania‐infected macrophages sequester endogenously synthesized parasite antigens from presentation to CD4⁺ T cells

1996 • 76 citations

Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages.

1996 • 72 citations

Localization and activity of various lysosomal proteases in Leishmania amazonensis-infected macrophages

1990 • 69 citations

Phosphomonoesterases of Leishmania mexicana mexicana and other flagellates

1987 • 58 citations

Distribution of mhc class i and of mhc class ii molecules in macrophages infected with Leishmania amazonensis

1994 • 58 citations

Leishmania donovani: Immunochemical localization and secretory mechanism of soluble acid phosphatase

1989 • 54 citations

Proteophosphoglycan secreted by Leishmania mexicana amastigotes causes vacuole formation in macrophages

1997 • 53 citations

Purification, partial characterization and immunolocalization of a proteophosphoglycan secreted by Leishmania mexicana amastigotes.

1995 • 52 citations

Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis.

1992 • 50 citations

Presentation via the class I pathway by Leishmania amazonensis-infected macrophages of an endogenous leishmanial antigen to CD8+ T cells.

1997 • 48 citations

Antigen presentation by Leishmania mexicana‐infected macrophages: Activation of helper T cells specific for amastigote cysteine proteinases requires intracellular killing of the parasites

1995 • 46 citations

Development of Drug Resistance by Staphylococci in Vitro and in Vivo

1963 • 44 citations

Transfer of phagocytosed particles to the parasitophorous vacuole of Leishmania mexicana is a transient phenomenon preceding the acquisition of annexin I by the phagosome

1997 • 43 citations

Lonely MHC molecules seeking immunogenic peptides for meaningful relationships

1995 • 41 citations

Antigen presentation by Leishmania mexicana‐infected macrophages: activation of helper T cells by a model parasite antigen secreted into the parasitophorous vacuole or expressed on the amastigote surface

1996 • 38 citations

Monoclonal antibodies to Leishmania mexicana promastigote antigens II. Cellular localization of antigens in promastigotes and infected macrophages

1991 • 37 citations

Leishmania mexicana: A cytochemical and quantitative study of lysosomal enzymes in infected rat bone marrow-derived macrophages

1987 • 35 citations

Depletion of secondary lysosomes in mouse macrophages infected withLeishmania mexicana amazonensis: A cytochemical study

1985 • 31 citations

Leishmania mexicana amazonensis: Attachment to the membrane of the phagocytic vacuole of macrophages in vivo

1981 • 18 citations

CD8+ T cells and immunity to intracellular pathogens

1993 • 15 citations