Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

1980 • 850 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication.

1981 • 531 citations

MONOCLONAL ANTIBODIES TO MOUSE MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS

1982 • 471 citations

A molecular model of MHC class-I-restricted antigen processing

1992 • 438 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

1990 • 377 citations

The Cell Biology of Antigen Processing and Presentation

1991 • 349 citations

Macropinosome maturation and fusion with tubular lysosomes in macrophages.

1993 • 332 citations

Glycoproteins of the lysosomal membrane.

1985 • 294 citations

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.

1992 • 277 citations

Multiplication of a Human Parasite ( Leishmania donovani ) in Phagolysosomes of Hamster Macrophages in Vitro

1976 • 274 citations

Mannose-6-phosphate receptors for lysosomal enzymes cycle between the Golgi complex and endosomes.

1986 • 270 citations

Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules.

1987 • 270 citations

Fusion of Host Cell Secondary Lysosomes with the Parasitophorous Vacuoles ofLeishmania mexicana-inlected Macrophages

1975 • 266 citations

Cathepsin D is membrane-associated in macrophage endosomes.

1988 • 259 citations

Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesicles.

1988 • 241 citations

Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH

1990 • 234 citations

Intracellular transport of MHC class II molecules

1992 • 222 citations

Presentation of Listeria monocytogenes to CD8+ T cells requires secretion of hemolysin and intracellular bacterial growth.

1990 • 208 citations

Monoclonal antibodies specific for Ia glycoproteins raised by immunization with activated T cells: possible role of T cellbound Ia antigens as targets of immunoregulatory T cells.

1984 • 190 citations

Leishmania Donovani. Hamster macrophage interactions in vitro: cell entry, intracellular survival, and multiplication of amastigotes

1978 • 183 citations

Parasite-accessory cell interactions in murine leishmaniasis. II. Leishmania donovani suppresses macrophage expression of class I and class II major histocompatibility complex gene products.

1987 • 178 citations

Functional heterogeneity of CD4+ T cells in leishmaniasis

1989 • 171 citations

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

1992 • 168 citations

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells.

1992 • 167 citations

A study of the differential respiratory burst activity elicited by promastigotes and amastigotes of Leishmania donovani in murine resident peritoneal macrophages.

1984 • 164 citations

Immunology of leishmaniasis

1992 • 162 citations

Role of L3T4+ and LyT-2+ cells in experimental visceral leishmaniasis.

1988 • 162 citations

Lymphoid Cell Surface Interaction Structures Detected Using Cytolysis‐Inhibiting Monoclonal Antibodies

1982 • 155 citations

Ia invariant chain detected on lymphocyte surfaces by monoclonal antibody

1982 • 145 citations

Intracellular transport and localization of major histocompatibility complex class II molecules and associated invariant chain.

1991 • 145 citations

Listeria monocytogenes-reactive T lymphocyte clones with cytolytic activity against infected target cells.

1986 • 134 citations

T-Cell Responses and Immunity to Experimental Infection with Leishmania Major

1989 • 125 citations

Elimination of CD4+ suppressor T cells from susceptible BALB/c mice releases CD8+ T lymphocytes to mediate protective immunity against Leishmania.

1989 • 114 citations

Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8⁺ T cells

1991 • 112 citations

Cellular and molecular mechanisms of intracellular symbiosis in leishmaniasis.

1983 • 111 citations

Kinetics of gamma interferon binding and induction of major histocompatibility complex class II mRNA in Leishmania-infected macrophages.

1988 • 103 citations

Plasticity of the tubular lysosomal compartment in macrophages

1990 • 103 citations

Induction of Th1 and Th2 CD4+ subsets during murine Leishmania major infection

1991 • 102 citations

Antigen presentation capacity of murine macrophages infected with Leishmania amazonensis amastigotes.

1993 • 102 citations

Differential expression of murine macrophage surface glycoprotein antigens in intracellular membranes

1987 • 98 citations

A modified colorimetric assay of macrophage activation for intracellular cytotoxicity against Leishmania parasites

1990 • 94 citations

Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing.

1990 • 81 citations

Localization of major histocompatibility complex class II molecules in phagolysosomes of murine macrophages infected with Leishmania amazonensis

1991 • 79 citations

Localization and activity of various lysosomal proteases in Leishmania amazonensis-infected macrophages

1990 • 69 citations

Cutaneous leishmaniasis. The defect in T cell influx in BALB/c mice.

1987 • 58 citations

Distribution of mhc class i and of mhc class ii molecules in macrophages infected with Leishmania amazonensis

1994 • 58 citations

Endolyn-78, a membrane glycoprotein present in morphologically diverse components of the endosomal and lysosomal compartments: implications for lysosome biogenesis.

1989 • 51 citations

Receptor-Mediated Entry of Peroxidases Into the Parasitophorous Vacuoles of Macrophages Infected With Leishmania Mexicana Amazonensis

1985 • 48 citations

Endocytic membrane traffic with respect to phagosomes in macrophages infected with non-pathogenic bacteria: phagosomal membrane acquires the same composition as lysosomal membrane.

1988 • 39 citations

Invariant chain — a regulator of antigen presentation

1992 • 38 citations

Acquisition of cell-mediated immunity to Leishmania. II. LSH gene regulation of accessory cell function.

1988 • 35 citations

Leishmania mexicana: A cytochemical and quantitative study of lysosomal enzymes in infected rat bone marrow-derived macrophages

1987 • 35 citations

Altered course of visceral leishmaniasis in mice expressing transgenic I‐E molecules

1992 • 35 citations

Modified lysosomal compartment as carrier of slowly and non-degradable tracers in macrophages.

1990 • 32 citations

Depletion of secondary lysosomes in mouse macrophages infected withLeishmania mexicana amazonensis: A cytochemical study

1985 • 31 citations

Antigens targeted to the Leishmania phagolysosome are processed for CD4⁺ T cell recognition

1993 • 26 citations

Presentation of Leishmania donovani promastigotes occurs via a brefeldin A‐sensitive pathway

1991 • 19 citations

Antibodies to rat liver cathepsins: characterization and use for the identification of enzyme precursors.

1986 • 19 citations

Endocytosis of Leishmania-infected macrophages. Fluorometry of pinocytic rate, lysosome-phagosome fusion and intralysosomal pH.

1980 • 14 citations

Effects of anti-membrane antibodies on killer T cells.

1982 • 9 citations

The Compartments of the Endocytic Pathway

1992 • 7 citations

Localization of MHC class II molecules in murine bone marrow-derived macrophages.

1991 • 5 citations

Protein Exchange Within the Lysosome and Pre-Lysosome Compartment: A Mechanism for Maintaining Organelle Functionality?

1992 • 2 citations