Vacuoles Induced by Helicobacter pylori Toxin Contain Both Late Endosomal and Lysosomal Markers

Helicobacter pyloriInfection and the Risk of Gastric Carcinoma

1991 • 3,869 citations

cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

1996 • 1,883 citations

Helicobacter pylori Infection and Gastric Lymphoma

1994 • 1,845 citations

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

1992 • 1,342 citations

rab5 controls early endosome fusion in vitro

1991 • 1,090 citations

Campylobacter pylori and Peptic Ulcer Disease

1989 • 760 citations

Rab 7: an important regulator of late endocytic membrane traffic.

1995 • 625 citations

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease.

1994 • 594 citations

Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin

1995 • 594 citations

Development of a Mouse Model of Helicobacter pylori Infection that Mimics Human Disease

1995 • 574 citations

Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.

1994 • 490 citations

Vacuolar ATPase activity is required for endosomal carrier vesicle formation.

1994 • 418 citations

Cytoplasmic dynein-dependent vesicular transport from early to late endosomes [published erratum appears in J Cell Biol 1994 Feb;124(3):397]

1993 • 408 citations

Rab GTPases in vesicular transport

1993 • 379 citations

Genetic analysis of the Helicobacter pylori vacuoiating cytotoxin: structural similarities with the IgA protease type of exported protein

1994 • 313 citations

The rab7 gtpase resides on a vesicular compartment connected to lysosomes

1995 • 297 citations

Effect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxin

1991 • 253 citations

Biogenesis of phagolysosomes: the 'kiss and run' hypothesis

1995 • 252 citations

Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesicles.

1988 • 241 citations

Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.

1994 • 232 citations

Bacterial protein toxins penetrate cells via a four‐step mechanism

1994 • 224 citations

Low pH Activates the Vacuolating Toxin of Helicobacter pylori, Which Becomes Acid and Pepsin Resistant

1995 • 217 citations

The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin

1997 • 216 citations

The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway

1996 • 175 citations

DUODENAL ULCER, CAMPYLOBACTER PYLORI, AND THE "LEAKING ROOF" CONCEPT

1988 • 166 citations

Bafilomycin A1 inhibits Helicobacter pylori‐induced vacuolization of HeLa cells

1993 • 124 citations

Helicobacter colonization and histopathological profile of chronic gastritis in patients with or without dyspepsia, mucosal erosion and peptic ulcer: A morphological approach to the study of ulcerogenesis in man

1992 • 99 citations

On vesicles and membrane compartments

1996 • 94 citations

Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies

1995 • 92 citations

Production of a Cytotoxin by Helicobacter pylori

1991 • 82 citations

Roles for mannose-6-phosphate receptors in lysosomal enzyme sorting, IGF-II binding and clathrin-coat assembly

1995 • 77 citations

Lipid Interaction of the 37‐kDa and 58‐kDa Fragments of the Helicobacter Pylori Cytotoxin

1995 • 58 citations

The New Path to Preventing Ulcers

1995 • 38 citations

Bacterial protein toxins

1995 • 32 citations