Transcriptional interference – a crash course

Mechanisms of gene silencing by double-stranded RNA

2004 • 2,439 citations

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

2002 • 1,612 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

Global Identification of Human Transcribed Sequences with Genome Tiling Arrays

2004 • 1,020 citations

Interspersed repeats and other mementos of transposable elements in mammalian genomes

1999 • 959 citations

The INK4a/ARF network in tumour suppression

2001 • 956 citations

Empirical Analysis of Transcriptional Activity in the Arabidopsis Genome

2003 • 906 citations

Widespread occurrence of antisense transcription in the human genome

2003 • 655 citations

Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene

2004 • 585 citations

Know Your Neighbors: Three Phenotypes in Null Mutants of the Myogenic bHLH Gene MRF4

1996 • 572 citations

A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression

2000 • 532 citations

Human 5′ → 3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

2004 • 456 citations

CONTROLLING ELEMENTS IN MAIZE

1974 • 408 citations

Epigenetic regulation of mammalian genomic imprinting

2004 • 395 citations

Intergenic Transcription and Developmental Remodeling of Chromatin Subdomains in the Human β-globin Locus

2000 • 344 citations

Retrotransposons as epigenetic mediators of phenotypic variation in mammals

2001 • 339 citations

Developmental regulation of β-globin gene switching

1988 • 328 citations

Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation

1986 • 312 citations

Promoter occlusion: Transcription through a promoter may inhibit its activity

1982 • 294 citations

In search of antisense

2004 • 293 citations

A Gene Expression Map for the Euchromatic Genome of Drosophila melanogaster

2004 • 291 citations

RegulonDB (version 4.0): transcriptional regulation, operon organization and growth conditions in Escherichia coli K-12

2003 • 265 citations

Combinatorial control of gene expression

2004 • 265 citations

Transcriptional collision between convergent genes in budding yeast

2002 • 261 citations

Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3′ end processing in the human alpha 2 globin gene.

1986 • 236 citations

Rapid Periodic Binding and Displacement of the Glucocorticoid Receptor during Chromatin Remodeling

2004 • 234 citations

Cooperation Between RNA Polymerase Molecules in Transcription Elongation

2003 • 228 citations

Many Human Genes Are Transcribed from the Antisense Promoter of L1 Retrotransposon

2002 • 223 citations

Transcription through the roadblocks: the role of RNA polymerase cooperation

2003 • 201 citations

Transcriptome analysis of Escherichia coli using high-density oligonucleotide probe arrays

2002 • 191 citations

Transcriptional Interference between Convergent Promoters Caused by Elongation over the Promoter

2004 • 183 citations

Transcriptional Interference by Independently Regulated Genes Occurs in Any Relative Arrangement of the Genes and Is Influenced by Chromosomal Integration Position

2002 • 166 citations

Promoter prediction analysis on the whole human genome

2004 • 160 citations

Genomic insulators: connecting properties to mechanism

2003 • 153 citations

RNAi Triggered by Symmetrically Transcribed Transgenes in Drosophila melanogaster

2002 • 150 citations

Three promoters near the termini of IS10: pIN, pOUT, and pIII

1983 • 142 citations

Role of transcriptional interference in the Drosophila melanogaster Adh promoter switch

1989 • 138 citations

Activities of constitutive promoters in Escherichia coli 1 1Edited by D. E. Draper

1999 • 136 citations

Promoter occlusion during ribosomal RNA transcription

1988 • 123 citations

Convergent transcription in bacteriophage λ: Interference with gene expression

1979 • 120 citations

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter

1998 • 115 citations

Position and density effects on repression by stationary and mobile DNA-binding proteins.

1989 • 115 citations

A Mathematical Model for Transcriptional Interference by RNA Polymerase Traffic in Escherichia coli

2004 • 113 citations

Autocatalytic RNA cleavage in the human β-globin pre-mRNA promotes transcription termination

2004 • 108 citations

Complex patterns of transcription at the insertion site of a retrotransposon in the mouse

2004 • 107 citations

Mfd, the bacterial transcription repair coupling factor: translocation, repair and termination

2004 • 95 citations

Gene Length and Proximity to Neighbors Affect Genome-Wide Expression Levels

2003 • 79 citations

Origins of Bidirectional Promoters: Computational Analyses of Intergenic Distance in the Human Genome

2003 • 79 citations

Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae

2000 • 78 citations

Bystander gene activation by a locus control region

2004 • 76 citations

Mechanisms of transcriptional repression

2001 • 76 citations

The cox protein of bacteriophage P2 inhibits the formation of the repressor protein and autoregulates the early operon.

1987 • 67 citations

Genetic evidence for promoter competition in Saccharomyces cerevisiae.

1988 • 67 citations

Regulation of transcription from tandem and convergent promoters

1982 • 63 citations

Transcriptional interference in transgenic plants

1991 • 62 citations

Historical Development of the Concept of the Gene

2002 • 60 citations

Transcription of unr (pstream of ‐as) down‐modulates N‐ras expression in vivo

1997 • 56 citations

Action at a distance in CI repressor regulation of the bacteriophage 186 genetic switch

2002 • 49 citations

Dual function of the copR gene product of plasmid pIP501

1997 • 48 citations

Isolated P2 RRNA Promoters of Escherichia coli are Strong Promoters that are Subject to Stringent Control

1994 • 38 citations

Elimination of Transcriptional Interference between Tandem Genes in Plant Cells

2001 • 37 citations

Promoter competition as a mechanism of transcriptional interference mediated by retrotransposons

2002 • 33 citations

The effects of DNA supercoiling on the expression of operons of the ilv regulon of Escherichia coli suggest a physiological rationale for divergently transcribed operons

2001 • 33 citations

Transcription through the yeast origin of replication ARS1 ends at the ABFI binding site and affects extrachromosomal maintenance of minichromosomes

1994 • 30 citations

The yeast actin intron contains a cryptic promoter that can be switched on by preventing transcriptional interference

1992 • 30 citations

Demonstration that the TyrR Protein and RNA Polymerase Complex Formed at the Divergent P3 Promoter Inhibits Binding of RNA Polymerase to the Major Promoter, P1, of the aroP Gene of Escherichia coli

1998 • 29 citations

Dissection of the switch between genes for replication and transfer of promiscuous plasmid RK2: basis of the dominance of trfAp over trbAp and specificity for KorA in controlling the switch

1997 • 28 citations

Transcriptional regulation of fis operon involves a module of multiple coupled promoters

2002 • 27 citations

Genetic Evidence for Promoter Competition in Saccharomyces cerevisiae

1988 • 23 citations

Tetracycline-dependent activation of an upstream promoter reveals transcriptional interference between tandem genes within T-DNA in tomato.

1997 • 21 citations

Regulation of phage Mu repressor transcription by IHF depends on the level of the early transcription

1989 • 17 citations

Convergent Transcription Units and Their Promoters at Both Ends of Pot2, an Inverted Repeat Transposon from the Rice Blast Fungus

1998 • 17 citations

Short-range compositional correlation in the yeast genome depends on transcriptional orientation

2004 • 12 citations

Mutually Exclusive Utilization of P _R and P _RM Promoters in Bacteriophage 434 O _R

2000 • 12 citations