The yeast actin intron contains a cryptic promoter that can be switched on by preventing transcriptional interference

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.

1980 • 567 citations

The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

1991 • 497 citations

RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA.

1983 • 415 citations

The Exon Theory of Genes

1987 • 395 citations

Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

1984 • 368 citations

Intron phylogeny: a new hypothesis

1991 • 361 citations

Improved plasmid vectors for the isolation of translational lac gene fusions

1984 • 323 citations

Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation

1986 • 312 citations

Promoter occlusion: Transcription through a promoter may inhibit its activity

1982 • 294 citations

Speculations on the early course of evolution.

1986 • 284 citations

Evidence that introns arose at proto-splice sites.

1989 • 235 citations

Tryptophan biosynthesis in Saccharomyces cerevisiae: control of the flux through the pathway

1978 • 189 citations

A transcription terminator located upstream of the mouse rDNA initiation site affects rRNA synthesis

1986 • 157 citations

A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter

1986 • 153 citations

A transcriptional terminator is a novel element of the promoter of the mouse ribosomal RNA gene

1986 • 136 citations

How were introns inserted into nuclear genes?

1989 • 131 citations

Molecular cloning of the actin gene from yeast Saccharomyces cerevisiae

1980 • 131 citations

Promoter occlusion during ribosomal RNA transcription

1988 • 123 citations

Different classes of polyadenylation sites in the yeast Saccharomyces cerevisiae.

1991 • 102 citations

The promoter-proximal rDNA terminator augments initiation by preventing disruption of the stable transcription complex caused by polymerase read-in.

1989 • 86 citations

Transcription terminates near the poly(A) site in the CYC1 gene of the yeast Saccharomyces cerevisiae.

1989 • 82 citations

Transcription by RNA polymerase II induces changes of DNA topology in yeast.

1988 • 82 citations

Bacteriophage T4 late promoters: mapping 5′ ends of T4 gene 23 mRNAs.

1982 • 73 citations

The splicing of maize transposable elements from pre-mRNA — a minireview

1989 • 50 citations

Origin of a "bridge" intron in the gene for a two-domain globin.

1991 • 50 citations

A New Type of Fusion Analysis Applicable to Many Organisms: Protein Fusions to the URA3 Gene of Yeast

1987 • 44 citations

Arrangement of genes TRP1 and TRP3 of Saccharomyces cerevisiae strains

1985 • 43 citations

TheTRP4gene ofSaccharomyces cerevisiae: isolation and structural analysis

1986 • 43 citations

Different Classes of Polyadenylation Sites in the Yeast Saccharomyces cerevisiae

1991 • 22 citations

The intron of the yeast actin gene contains the promoter for an antisense RNA

1990 • 20 citations

Expression of lacZ gene fusions affects downstream transcription in yeast

1991 • 7 citations