Mechanisms of transcriptional repression

Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology

1987 • 4,385 citations

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

1988 • 3,957 citations

Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid

1999 • 882 citations

A Third Recognition Element in Bacterial Promoters: DNA Binding by the α Subunit of RNA Polymerase

1993 • 790 citations

Transcription activation by catabolite activator protein (CAP)

1999 • 781 citations

Nucleic Acids and Molecular Biology

1994 • 777 citations

The three operators of the lac operon cooperate in repression.

1990 • 487 citations

H‐NS: a modulator of environmentally regulated gene expression

1997 • 482 citations

Eubacterial sigma-factors

1998 • 478 citations

The Bacterial Enhancer-Dependent ς⁵⁴(ς^N) Transcription Factor

2000 • 419 citations

Promoters largely determine the efficiency of repressor action.

1988 • 352 citations

THE ANTI-SIGMA FACTORS

1998 • 327 citations

Competition among seven Escherichia coli sigma subunits: relative binding affinities to the core RNA polymerase

2000 • 301 citations

UPs and downs in bacterial transcription initiation: the role of the alpha subunit of RNA polymerase in promoter recognition

2000 • 267 citations

Negative regulation by RpoS: a case of sigma factor competition

1998 • 263 citations

Untwist and shout: a heavy metal-responsive transcriptional regulator

1992 • 235 citations

The chromatin-associated protein H-NS alters DNA topology in vitro.

1994 • 225 citations

A stationary phase protein in Escherichia coli with binding activity to the major σ subunit of RNA polymerase

1998 • 181 citations

Anti-sigma factors

1999 • 175 citations

Eubacterial sigma-factors

1998 • 171 citations

A DNA architectural protein couples cellular physiology and DNA topology in Escherichia coli

1999 • 160 citations

Plasmid copy-number control and better-than-random segregation genes of pSM19035 share a common regulator

2000 • 147 citations

Protein–Protein Contacts that Activate and Repress Prokaryotic Transcription

1998 • 136 citations

Two different mechanisms mediate catabolite repression of the Bacillus subtilis levanase operon

1995 • 135 citations

The bacterial DNA-binding protein H-NS represses ribosomal RNA transcription by trapping RNA polymerase in the initiation complex

2000 • 117 citations

Inhibition of Transcription Initiation buIacRepressor

1995 • 117 citations

The flagellar anti-ς factor FlgM actively dissociates Salmonella typhimurium ς²⁸ RNA polymerase holoenzyme

1998 • 110 citations

A flexible partnership: the CytR anti‐activator and the cAMP–CRP activator protein, comrades in transcription control

1996 • 107 citations

Upstream A-tracts increase bacterial promoter activity through interactions with the RNA polymerase α subunit

1998 • 106 citations

Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism

2000 • 103 citations

Mechanism of Autoregulation by an Archaeal Transcriptional Repressor

2000 • 101 citations

Stalling of Escherichia coli RNA Polymerase in the +6 to +12 Region in Vivo is Associated with Tight Binding to Consensus Promoter Elements

1994 • 95 citations

Activation and Repression of Transcription by Differential Contact: Two Sides of a Coin

1998 • 94 citations

Repression of Transcription Initiation in Bacteria

1999 • 92 citations

Histone‐like protein HU as a specific transcriptional regulator: co‐factor role in repression of gal transcription by GAL repressor

1996 • 90 citations

Activator-dependent preinduction binding of .sigma.-70 RNA polymerase at the metal-regulated mer promoter

1990 • 85 citations

Inhibition of Escherichia coli RNA polymerase by bacteriophage T4 AsiA 1 1Edited by E. Ebright

1998 • 85 citations

Promoter properties and negative regulation of the uvrA gene by the LexA represser and its amino-terminal DNA binding domain

1987 • 78 citations

Lac and λ repressors relieve silencing of the Escherichia coli bgl promoter. activation by alteration of a repressing nucleoprotein complex

1998 • 72 citations

Suppression of FNR‐dependent transcription activation at the Escherichia coli nir promoter by Fis, IHF and H‐NS: modulation of transcription initiation by a complex nucleo‐protein assembly

2000 • 72 citations

lac repressor acts by modifying the initial transcribing complex so that it cannot leave the promoter

1991 • 71 citations

lac Repressor forms stable loops in vitro with supercoiled wild-type lac DNA containing all three natural lac operators

1990 • 63 citations

Multifunctional repressor KorB can block transcription by preventing isomerization of RNA polymerase – promoter complexes

1993 • 63 citations

Context-dependent Effects of Upstream A-Tracts

1994 • 62 citations

Transcription Activation or Repression by Phage Φ29 Protein p4 Depends on the Strength of the RNA Polymerase–Promoter Interactions

1997 • 60 citations

Functional and physical characterization of transcription initiation complexes in the bacteriophage lambda OR region.

1985 • 60 citations

Coordinated Repression In Vitro of the Divergent fepA-fes Promoters of Escherichia coli by the Iron Uptake Regulation (Fur) Protein

1998 • 59 citations

A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.

1991 • 59 citations

Protein p4 represses phage phi 29 A2c promoter by interacting with the alpha subunit of Bacillus subtilis RNA polymerase.

1996 • 56 citations

Repression of the Klebsiella aerogenes nac promoter

1995 • 55 citations

Activation and repression of transcription at two different phage phi29 promoters are mediated by interaction of the same residues of regulatory protein p4 with RNA polymerase.

1996 • 55 citations

Evidence of an Unusually Long Operator for the Fur Repressor in the Aerobactin Promoter of Escherichia coli

2000 • 54 citations

The Downstream Regulatory Element of the proU Operon of Salmonella typhimurium Inhibits Open Complex Formation by RNA Polymerase at a Distance

2000 • 50 citations

FNR-dependent repression of ndh gene expression requires two upstream FNR-binding sites

1997 • 48 citations

Transcription activation by phage phi29 protein p4 is mediated by interaction with the alpha subunit of Bacillus subtilis RNA polymerase.

1996 • 48 citations

Conserved C-terminal region of global repressor KorA of broad-host-range plasmid RK2 is required for co-operativity between KorA and a second RK2 global regulator, KorB

1999 • 48 citations

The Spo0A Protein of Bacillus subtilis Inhibits Transcription of the abrB Gene without Preventing Binding of the Polymerase to the Promoter

1996 • 46 citations

DNA structure and transcription

1999 • 43 citations

Transcription Regulation by Repressosome and by RNA Polymerase Contact

1998 • 42 citations

Repression at a distance by the global regulator KorB of promiscuous IncP plasmids

1999 • 42 citations

Repression and activation of promoter-bound RNA polymerase activity by gal repressor 1 1Edited by R. Ebright

1997 • 40 citations

Dual regulation of open-complex formation and promoter clearance by Arc explains a novel repressor to activator switch.

1996 • 38 citations

Phage phi 29 regulatory protein p4 stabilizes the binding of the RNA polymerase to the late promoter in a process involving direct protein-protein contacts.

1992 • 37 citations

Occlusion of RNA Polymerase by Oligomerization of DnaA Protein over the dnaA Promoter of Escherichia coli

1997 • 35 citations

Some repressors of bacterial transcription

1998 • 35 citations

On the mechanism of inhibition of phage T7 RNA polymerase by lac repressor 1 1Edited by R. Ebright

1998 • 34 citations

Principles Governing the Activity of E. coli Promoters

1990 • 31 citations

Demonstration that the TyrR Protein and RNA Polymerase Complex Formed at the Divergent P3 Promoter Inhibits Binding of RNA Polymerase to the Major Promoter, P1, of the aroP Gene of Escherichia coli

1998 • 29 citations

Antagonistic control of the Escherichia coli bgl promoter by FIS and CAP in vitro

2000 • 27 citations

Identification of a Surface of FNR Overlapping Activating Region 1 That Is Required for Repression of Gene Expression

1999 • 21 citations

Design of CytR regulated, cAMP-CRP dependent class II promoters in Escherichia coli: RNA polymerase-promoter interactions modulate the efficiency of CytR repression

1997 • 21 citations

Mechanism of Repression of the aroP P2 Promoter by the TyrR Protein of Escherichia coli

1999 • 13 citations