Promoter competition as a mechanism of transcriptional interference mediated by retrotransposons

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

1993 • 858 citations

A position-effect assay for boundaries of higher order chromosomal domains

1991 • 616 citations

DNA position-specific repression of transcription by a Drosophila zinc finger protein.

1992 • 418 citations

Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.

1996 • 406 citations

Vectors for P-Mediated Transformation in Drosophila

1988 • 399 citations

A group of scs elements function as domain boundaries in an enhancer-blocking assay.

1992 • 383 citations

Characterization of the chicken β-globin insulator

1997 • 381 citations

The Downstream Promoter Element DPE Appears To Be as Widely Used as the TATA Box in Drosophila Core Promoters

2000 • 347 citations

Developmental regulation of β-globin gene switching

1988 • 328 citations

Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation

1986 • 312 citations

Enhancer–promoter specificity mediated by DPE or TATA core promoter motifs

2001 • 262 citations

The 87A7 chromomere

1985 • 249 citations

Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex.

1996 • 237 citations

Different core promoters possess distinct regulatory activities in the Drosophila embryo

1998 • 219 citations

Loss of Insulator Activity by Paired Su(Hw) Chromatin Insulators

2001 • 209 citations

Effects of cis Arrangement of Chromatin Insulators on Enhancer-Blocking Activity

2001 • 193 citations

Spatial and temporal pattern of hsp26 expression during normal development.

1986 • 193 citations

The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain

2000 • 190 citations

Selectivity, sharing and competitive interactions in the regulation of Hoxb genes

1998 • 167 citations

The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo.

1996 • 166 citations

Group II Intron Domain 5 Facilitates a trans-Splicing Reaction

1988 • 161 citations

GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo

1998 • 153 citations

A Group of scs Elements Function as Domain Boundaries in an Enhancer-Blocking Assay

1992 • 136 citations

A Novel cis -Regulatory Element, the PTS, Mediates an Anti-Insulator Activity in the Drosophila Embryo

1999 • 122 citations

Promoter elements in Drosophila melanogaster revealed by sequence analysis.

1995 • 120 citations

Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain- of-function of posterior Hoxd genes

1997 • 120 citations

Characterization of the transvection mediating region of the Abdominal-B locus in Drosophila

1999 • 116 citations

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter

1998 • 115 citations

Individual stage selector element mutations lead to reciprocal changes in beta- vs. epsilon-globin gene transcription: genetic confirmation of promoter competition during globin gene switching.

1992 • 101 citations

Molecular analysis of the zeste-white interaction reveals a promoter-proximal element essential for distant enhancer-promoter communication.

1992 • 96 citations

Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae

2000 • 78 citations

Insulating DNA directs ubiquitous transcription of the Drosophila melanogaster alpha 1-tubulin gene.

1994 • 59 citations

Mobilization of two retroelements, ZAM and Idefix, in a novel unstable line of Drosophila melanogaster

1999 • 55 citations

Somatic Reversion of Chromosomal Position Effects in Drosophila melanogaster

1996 • 52 citations

Invertebrate retroviruses: ZAM a new candidate in D.melanogaster

1997 • 51 citations

Coupling of Enhancer and Insulator Properties Identified in Two Retrotransposons Modulates Their Mutagenic Impact on Nearby Genes

2002 • 49 citations

Promoter suppression in cultured mammalian cells can be blocked by the chicken β-globin chromatin insulator 5′HS4 and matrix/scaffold attachment regions11Edited by M. Yaniv

2001 • 48 citations

Expression of the Idefix retrotransposon in early follicle cells in the germarium of Drosophila melanogaster is determined by its LTR sequences and a specific genomic context

2002 • 22 citations

Insulating DNA Directs Ubiquitous Transcription of the Drosophila melanogaster α1-tubulin Gene

1994 • 17 citations

The Integration Machinery of ZAM, a Retroelement from Drosophila melanogaster , Acts as a Sequence-Specific Endonuclease

1999 • 16 citations

Aberrant pre-mRNA maturation is caused by LINE insertions into introns of thewhitegene ofDrosophila melanogaster

1995 • 11 citations

Impact of multiple insertions of two retroelements, ZAM and Idefix at an euchromatic locus.

2000 • 7 citations