TRPV1 shows dynamic ionic selectivity during agonist stimulation

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

1998 • 3,026 citations

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

1996 • 1,703 citations

The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway

2001 • 1,532 citations

Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor

2006 • 1,343 citations

An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

2002 • 959 citations

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

2001 • 714 citations

Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants

1992 • 668 citations

PERMEATION AND SELECTIVITY OF TRP CHANNELS

2005 • 532 citations

Lighting up the Senses: FM1-43 Loading of Sensory Cells through Nonselective Ion Channels

2003 • 516 citations

Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

2001 • 493 citations

Direct Phosphorylation of Capsaicin Receptor VR1 by Protein Kinase Cε and Identification of Two Target Serine Residues

2002 • 455 citations

Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)

2003 • 429 citations

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

2007 • 423 citations

Pore dilation of neuronal P2X receptor channels

1999 • 408 citations

Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory Neurons and Mediates Inflammatory Heat Hyperalgesia through TRPV1 Sensitization

2004 • 401 citations

Camphor Activates and Strongly Desensitizes the Transient Receptor Potential Vanilloid Subtype 1 Channel in a Vanilloid-Independent Mechanism

2005 • 399 citations

Ion‐concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction.

1979 • 394 citations

The permeability of the endplate channel to organic cations in frog muscle.

1980 • 362 citations

Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds

1999 • 355 citations

Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X₇ receptor

1999 • 345 citations

Protein kinase A regulates calcium permeability of NMDA receptors

2006 • 319 citations

Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

2005 • 297 citations

Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats

1996 • 296 citations

INTRAVESICAL CAPSAICIN AND RESINIFERATOXIN THERAPY: SPICING UP THE WAYS TO TREAT THE OVERACTIVE BLADDER

1999 • 272 citations

The vanilloid (capsaicin) receptor: Receptor types and species differences

1994 • 196 citations

The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat

2000 • 190 citations

State-dependent cross-inhibition between transmitter-gated cation channels

2000 • 186 citations

Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties

2000 • 180 citations

Extracellular Cations Sensitize and Gate Capsaicin Receptor TRPV1 Modulating Pain Signaling

2005 • 177 citations

Contribution of the Selectivity Filter to Inactivation in Potassium Channels

1999 • 171 citations

Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus In vitro

2002 • 158 citations

Biphasic Currents Evoked by Chemical or Thermal Activation of the Heat-gated Ion Channel, TRPV3

2005 • 157 citations

TRPV1 Acts as Proton Channel to Induce Acidification in Nociceptive Neurons

2004 • 150 citations

Polyamines Are Potent Ligands for the Capsaicin Receptor TRPV1

2006 • 149 citations

Similarities and differences in the currents activated by capsaicin, piperine, and zingerone in rat trigeminal ganglion cells

1996 • 137 citations

Differential regulation of evoked peptide release by voltage-sensitive calcium channels in rat sensory neurons

1996 • 112 citations

Pathobiological reactions of C‐fibre primary sensory neurones to peripheral nerve injury

1992 • 111 citations

TRPV1 regulators mediate gentamicin penetration of cultured kidney cells

2005 • 108 citations

The Responses of Rat Trigeminal Ganglion Neurons to Capsaicin and Two Nonpungent Vanilloid Receptor Agonists, Olvanil and Glyceryl Nonamide

1997 • 105 citations

Activity-Dependent Plasticity of the NMDA-Receptor Fractional Ca2+ Current

2007 • 102 citations

The effect of capsaicin on voltage‐gated calcium currents and calcium signals in cultured dorsal root ganglion cells

1990 • 100 citations

Conformational changes of pore helix coupled to gating of TRPV5 by protons

2005 • 98 citations

Dynamic Selectivity Filters in Ion Channels

1999 • 91 citations

Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore

2001 • 79 citations

Control of P2X2 Channel Permeability by the Cytosolic Domain

2002 • 66 citations

Contribution of Transmembrane Regions to ATP-gated P2X2 Channel Permeability Dynamics

2004 • 64 citations

Structural insight into Ca ²⁺ specificity in tetrameric cation channels

2007 • 38 citations

Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats

1996 • 22 citations