Contribution of Transmembrane Regions to ATP-gated P2X2 Channel Permeability Dynamics

THE GREEN FLUORESCENT PROTEIN

1998 • 5,991 citations

Molecular Physiology of P2X Receptors

2002 • 2,845 citations

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

1996 • 1,703 citations

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

1994 • 924 citations

ION CHANNELS IN EXCITABLE MEMBRANES

1978 • 832 citations

Rapid Secretion of Interleukin-1β by Microvesicle Shedding

2001 • 828 citations

Open channel structure of MscL and the gating mechanism of mechanosensitive channels

2002 • 596 citations

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels

1998 • 540 citations

Spatiotemporal Dynamics of Inositol 1,4,5-Trisphosphate That Underlies Complex Ca ²⁺ Mobilization Patterns

1999 • 500 citations

P2X₇Receptor-Mediated Release of Excitatory Amino Acids from Astrocytes

2003 • 479 citations

Hetero-oligomeric Assembly of P2X Receptor Subunits

1999 • 411 citations

Pore dilation of neuronal P2X receptor channels

1999 • 408 citations

Molecular physiology of p2x receptors and atp signalling at synapses

2001 • 368 citations

The permeability of the endplate channel to organic cations in frog muscle.

1980 • 362 citations

Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds

1999 • 355 citations

A real-time view of life within 100 nm of the plasma membrane

2001 • 352 citations

The gating mechanism of the large mechanosensitive channel MscL

2001 • 350 citations

Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X₇ receptor

1999 • 345 citations

Contribution of Calcium Ions to P2X Channel Responses

2004 • 286 citations

Energetics of Pore Opening in a Voltage-Gated K+ Channel

2002 • 284 citations

Allosteric Control of Gating and Kinetics at P2X₄Receptor Channels

1999 • 279 citations

ATP induces nucleotide permeability in rat mast cells

1979 • 252 citations

Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization

2000 • 228 citations

Neuronal P2X receptors: localisation and functional properties

2000 • 215 citations

Identification of amino acid residues contributing to the pore of a P2X receptor

1997 • 207 citations

Subunit Arrangement in P2X Receptors

2003 • 205 citations

Scanning the Intracellular S6 Activation Gate in the Shaker K+ Channel

2002 • 171 citations

P2X7 Receptor Cell Surface Expression and Cytolytic Pore Formation Are Regulated by a Distal C-terminal Region

2003 • 168 citations

Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes.

1994 • 168 citations

P2X Receptor Trafficking in Neurons Is Subunit Specific

2002 • 161 citations

Role for P2X Receptors in Long-Term Potentiation

2002 • 154 citations

A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method.

1998 • 136 citations

Pentameric assembly of a neuronal glutamate transporter

2000 • 124 citations

Amino Acid Residues Involved in Gating Identified in the First Membrane-spanning Domain of the Rat P2X2 Receptor

2001 • 119 citations

Contribution of Individual Subunits to the Multimeric P2X₂ Receptor: Estimates based on Methanethiosulfonate Block at T336C

1999 • 118 citations

Trimeric Architecture of Homomeric P2X2 and Heteromeric P2X1+2 Receptor Subtypes

2004 • 118 citations

A Domain Contributing to the Ion Channel of ATP-Gated P2X₂Receptors Identified by the Substituted Cysteine Accessibility Method

1998 • 117 citations

Conformational Rearrangements Associated with the Gating of the G Protein-Coupled Potassium Channel Revealed by FRET Microscopy

2003 • 115 citations

A fluorophore attached to nicotinic acetylcholine receptor βM2 detects productive binding of agonist to the αδ site

2004 • 101 citations

ATP Binding at Human P2X1 Receptors

2004 • 100 citations

Helical Structure of the Cooh Terminus of S3 and Its Contribution to the Gating Modifier Toxin Receptor in Voltage-Gated Ion Channels

2001 • 98 citations

Polar Residues of the Second Transmembrane Domain Influence Cation Permeability of the ATP-gated P2X2 Receptor

2001 • 92 citations

Dynamic Selectivity Filters in Ion Channels

1999 • 91 citations

Identification of a Trafficking Motif Involved in the Stabilization and Polarization of P2X Receptors

2004 • 87 citations

Structural changes during ion channel gating

2004 • 83 citations

Density‐dependent changes of the pore properties of the P2X₂ receptor channel

2004 • 80 citations

Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X ₂ -green fluorescent protein receptors

2001 • 75 citations

Comparison of adenosine triphosphate‐ and nicotine‐activated inward currents in rat phaeochromocytoma cells.

1991 • 75 citations

The α-Helix and the Organization and Gating of Channels

2002 • 67 citations

Control of P2X2 Channel Permeability by the Cytosolic Domain

2002 • 66 citations

Monomeric and Dimeric Byproducts are the Principal Functional Elements of Higher Order P2X₁Concatamers

2003 • 62 citations

A Wave in the Earth

1996 • 62 citations

Time-Resolved Measurement of State-Specific P2X₂Ion Channel Cytosolic Gating Motions

2004 • 61 citations

The First Transmembrane Domain of the P2X Receptor Subunit Participates in the Agonist-induced Gating of the Channel

2001 • 53 citations

Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: Electrophysiology-coordinated photochemistry and mass spectrometry

2003 • 51 citations

On the Contribution of the First Transmembrane Domain to Whole-Cell Current through an ATP-Gated Ionotropic P2X Receptor

2001 • 47 citations

Pore formation is not associated with macroscopic redistribution of P2X7 receptors

2002 • 44 citations

Scanning mutagenesis of the putative transmembrane segments of K _ir 2.1, an inward rectifier potassium channel

1997 • 37 citations

Interaction between cysteines introduced into each transmembrane domain of the rat P2X₂ receptor

2003 • 16 citations