TRPV1 regulators mediate gentamicin penetration of cultured kidney cells

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

1998 • 3,026 citations

ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures

2003 • 2,386 citations

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

2001 • 1,240 citations

Heat-Evoked Activation of the Ion Channel, TRPV4

2002 • 966 citations

TRPV3 is a calcium-permeable temperature-sensitive cation channel

2002 • 870 citations

TRPV3 is a temperature-sensitive vanilloid receptor-like protein

2002 • 811 citations

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

2002 • 758 citations

TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells

2004 • 712 citations

TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization

2002 • 700 citations

Kinetics of the receptor current in bullfrog saccular hair cells

1983 • 539 citations

A Modular PIP ₂ Binding Site as a Determinant of Capsaicin Receptor Sensitivity

2003 • 521 citations

Lighting up the Senses: FM1-43 Loading of Sensory Cells through Nonselective Ion Channels

2003 • 516 citations

The TRPM7 channel is inactivated by PIP2 hydrolysis

2002 • 509 citations

Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

2001 • 493 citations

FM1-43 Dye Behaves as a Permeant Blocker of the Hair-Cell Mechanotransducer Channel

2001 • 429 citations

A suggested approach to once‐daily aminoglycoside dosing.

1995 • 425 citations

TRPM5 Is a Voltage-Modulated and Ca2+-Activated Monovalent Selective Cation Channel

2003 • 386 citations

Aminoglycoside toxicity - a review of clinical studies published between 1975 and 1982

1984 • 352 citations

Voltage Dependence of the Ca2+-activated Cation Channel TRPM4

2003 • 348 citations

Molecular and Functional Characterization of the Melastatin-related Cation Channel TRPM3

2003 • 345 citations

Structural determinant of TRPV1 desensitization interacts with calmodulin

2003 • 340 citations

The Role of Calcium in the Desensitization of Capsaicin Responses in Rat Dorsal Root Ganglion Neurons

1997 • 335 citations

The actions of calcium on the mechano‐electrical transducer current of turtle hair cells.

1991 • 315 citations

Specific association of the gene product of PKD2 with the TRPC1 channel

1999 • 297 citations

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist

2003 • 267 citations

Blockage of the transduction channels of hair cells in the bullfrog's sacculus by aminoglycoside antibiotics

1989 • 257 citations

Iodo-Resiniferatoxin, a New Potent Vanilloid Receptor Antagonist

2001 • 256 citations

Comparison of Human TRPC3 Channels in Receptor-activated and Store-operated Modes

2002 • 231 citations

Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment

1985 • 222 citations

Polycystins and mechanosensation in renal and nodal cilia

2004 • 217 citations

Regulation of a Transient Receptor Potential (TRP) Channel by Tyrosine Phosphorylation

2003 • 197 citations

Transducing Touch in Caenorhabditis elegans

2003 • 165 citations

Anion Permeation in Ca2+-Activated Cl− Channels

2000 • 163 citations

Hearing loss and nephrotoxicity in long-term aminoglycoside treatment in patients with tuberculosis.

2002 • 162 citations

Current understanding of mammalian TRP homologues

2002 • 158 citations

The effects of calcium buffering and cyclic AMP on mechano‐electrical transduction in turtle auditory hair cells

1997 • 154 citations

TRPV1 Acts as Proton Channel to Induce Acidification in Nociceptive Neurons

2004 • 150 citations

Vanilloid and TRP channels: a family of lipid-gated cation channels

2002 • 149 citations

Potassium and Sodium Binding to the Outer Mouth of the K⁺ Channel

1999 • 140 citations

Tight junction proteins ZO-1, ZO-2, and occludin along isolated renal tubules

2000 • 140 citations

Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53 cDNAs in a mammalian translation system

2002 • 136 citations

Isolation of an aminoglycoside receptor from guinea pig inner ear tissues and kidney

1979 • 131 citations

Anandamide Activates Vanilloid Receptor 1 (VR1) at Acidic pH in Dorsal Root Ganglia Neurons and Cells Ectopically Expressing VR1

2001 • 128 citations

Cloning and Functional Expression of Human Short TRP7, a Candidate Protein for Store-operated Ca2+ Influx

2002 • 126 citations

Cold transduction in rat trigeminal ganglia neurons in vitro

2003 • 117 citations

Insights into Ototoxicity

1999 • 112 citations

Can pharmacokinetic dosing decrease nephrotoxicity associated with aminoglycoside therapy.

1993 • 111 citations

Vertebrate and invertebrate TRPV-like mechanoreceptors

2003 • 109 citations

Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca ²⁺ entry

1996 • 105 citations

An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions.

1985 • 104 citations

Vanilloid Receptors in Hearing: Altered Cochlear Sensitivity by Vanilloids and Expression of TRPV1 in the Organ of Corti

2003 • 101 citations

TRPC4 currents have properties similar to the pacemaker current in interstitial cells of Cajal

2002 • 100 citations

The Tissue Distribution and Functional Characterization of Human VR1

2001 • 97 citations

Uptake of Gentamicin by Bullfrog Saccular Hair Cells in vitro

2003 • 96 citations

Gentamicin traffics retrograde through the secretory pathway and is released in the cytosol via the endoplasmic reticulum

2004 • 94 citations

Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells

1987 • 93 citations

Lysosomal targeting and accumulation of aminoglycoside antibiotics in sensory hair cells

1997 • 87 citations

Ototoxicity: bioprotective mechanisms

2003 • 85 citations

TRPs Make Sense

2003 • 85 citations

Specific binding of [3H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypothalamus, reticular formation and ventral thalamus membrane preparations

1996 • 80 citations

Cytoplasmic and intra-nuclear binding of gentamicin does not require endocytosis

2005 • 75 citations

Molecular determinants of Au(CN)₂⁻ binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl⁻ channel pore

2002 • 72 citations

Differential Activation and Desensitization of Sensory Neurons by Resiniferatoxin

1997 • 72 citations

Aminoglycoside Pretreatment Partially Restores the Function of Truncated V₂Vasopressin Receptors Found in Patients with Nephrogenic Diabetes Insipidus

2002 • 63 citations

K+-induced motility and depolarization of cochlear hair cells. Direct evidence for a new pathophysiological mechanism in M�ni�re's disease

1986 • 60 citations

Junctional complexes of the tubular cells in the human kidney as revealed with freeze-fracture

1975 • 55 citations

Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat

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Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid

2003 • 47 citations

Characterization of the Functional Coupling of Bovine Brain Vacuolar-type H+-translocating ATPase

2003 • 42 citations

Mechanosensitive Calcium Entry and Mobilization in Renal A6 Cells

1999 • 42 citations

Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice

2004 • 38 citations

Intersegment Hydrogen Bonds as Possible Structural Determinants of the N/Q/R Site in Glutamate Receptors

1999 • 30 citations

Handbook of Ototoxicity

2019 • 28 citations

An isocratic separation of underivatized gentamicin components, 1H NMR assignment and protonation pattern

2003 • 26 citations

Antimicrobial Chemotherapy in the Control of Surgical Infectious Complications

1999 • 26 citations

Influence of pH on the ototoxicity of cisplatin: a round window application study

2003 • 25 citations

Transient Receptor Potential Protein as a Novel Non-Voltage-Gated Ca2+ Entry Channel Involved in Diverse Pathophysiological Functions

2003 • 19 citations

Nystatin and valinomycin induce tubuloglomerular feedback

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Olfactory Adaptation inDrosophilaLarvae

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Changes in Renal Handling of Platinum in Cisplatinum-Treated Rats Following Induction of Metabolic Acidosis or Alkalosis

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The key role of aminoglycosides in antibacterial therapy and prophylaxis

1984 • 11 citations

The pig mesonephros

1983 • 10 citations

Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs.

1993 • 10 citations

The pig mesonephros

1983 • 10 citations

Influence of serum protein binding on the uptake and retention of idarubicin by sensitive and multidrug resistant human leukemic cells

1999 • 8 citations

GLYCINE RECEPTORS: WHAT GETS IN AND WHY?

1999 • 8 citations

cDNA cloning and characterization of an osmotically sensitive TRP channel from ascidian eggs

2003 • 8 citations

Membrane specializations in the human organ of corti

1988 • 5 citations

Cell Potential of Isolated Outer Hair Cells as a Function of Extracellular K<sup>+</sup> Concentration

1993 • 3 citations