Microarray Analysis of Alternative Splicing

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Mechanisms of Alternative Pre-Messenger RNA Splicing

2003 • 2,547 citations

Listening to silence and understanding nonsense: exonic mutations that affect splicing

2002 • 2,143 citations

Human Gene Mutation Database (HGMD^®): 2003 update

2003 • 1,737 citations

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

2003 • 1,406 citations

Function of alternative splicing

2004 • 1,382 citations

The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences

1992 • 1,338 citations

A genomic view of alternative splicing

2002 • 1,307 citations

Understanding alternative splicing: towards a cellular code

2005 • 1,258 citations

Pre-mRNA splicing and human disease

2003 • 1,242 citations

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

2002 • 1,026 citations

A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

1998 • 745 citations

Variation in alternative splicing across human tissues.

2004 • 537 citations

Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

2003 • 524 citations

Experimental annotation of the human genome using microarray technology

2001 • 446 citations

Genomewide Analysis of mRNA Processing in Yeast Using Splicing-Specific Microarrays

2002 • 406 citations

Genome-wide detection of tissue-specific alternative splicing in the human transcriptome

2002 • 403 citations

Are splicing mutations the most frequent cause of hereditary disease?

2005 • 382 citations

Revealing Global Regulatory Features of Mammalian Alternative Splicing Using a Quantitative Microarray Platform

2004 • 320 citations

Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae

1999 • 320 citations

Human Gene Mutation Database?A biomedical information and research resource

2000 • 278 citations

Splice variants as cancer biomarkers

2004 • 259 citations

Stochastic yet biased expression of multiple Dscam splice variants by individual cells

2004 • 257 citations

Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

2006 • 216 citations

Finding signals that regulate alternative splicing in the post-genomic era.

2002 • 214 citations

Profiling alternative splicing on fiber-optic arrays

2002 • 211 citations

Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

1999 • 200 citations

Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast

2000 • 173 citations

Alternative splicing of conserved exons is frequently species-specific in human and mouse

2004 • 152 citations

Low conservation of alternative splicing patterns in the human and mouse genomes

2003 • 148 citations

Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications

2004 • 141 citations

Conservation of human alternative splice events in mouse

2003 • 135 citations

Predicting Splice Variant from DNA Chip Expression Data

2001 • 121 citations

Gene structure-based splice variant deconvolution using a microarry platform

2003 • 102 citations

Detecting tissue-specific regulation of alternative splicing as a qualitative change in microarray data

2004 • 102 citations

Detection and measurement of alternative splicing using splicing-sensitive microarrays

2005 • 99 citations

Long‐lasting acetylcholinesterase splice variations in anticholinesterase‐treated Alzheimer's disease patients

2004 • 93 citations

Alternative Splicing Microarrays Reveal Functional Expression of Neuron-specific Regulators in Hodgkin Lymphoma Cells

2004 • 88 citations

Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing

2003 • 85 citations

The relevance of alternative RNA splicing to pharmacogenomics

2003 • 84 citations

p53: link to the past, bridge to the future

2005 • 81 citations

Analysis of alternative splicing with microarrays: successes and challenges.

2004 • 71 citations

A microarray configuration to quantify expression levels and relative abundance of splice variants

2005 • 70 citations

Apoptosis-modulating interaction of the neuregulin/erbB pathway with antracyclines in regulating Bcl-xS and Bcl-xL in cardiomyocytes

2005 • 69 citations

Evolutionarily conserved and diverged alternative splicing events show different expression and functional profiles

2005 • 68 citations

Vascular endothelial growth factors and angiogenesis.

2000 • 63 citations

Inferring global levels of alternative splicing isoforms using a generative model of microarray data

2006 • 62 citations

ANOSVA: a statistical method for detecting splice variation from expression data

2005 • 55 citations

Human Pax-5 C-terminal Isoforms Possess Distinct Transactivation Properties and Are Differentially Modulated in Normal and Malignant B Cells

2004 • 44 citations

Determination of tumour marker genes from gene expression data

2005 • 41 citations

Identification of human exons overexpressed in tumors through the use of genome and expressed sequence data

2005 • 25 citations

Splicing factors are differentially expressed in tumors.

2004 • 25 citations

Candidates for tumor-specific alternative splicing

2005 • 19 citations