Analysis of alternative splicing with microarrays: successes and challenges.

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 3,126 citations

High density synthetic oligonucleotide arrays

1999 • 2,256 citations

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

2003 • 1,406 citations

A genomic view of alternative splicing

2002 • 1,307 citations

Drosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity

2000 • 1,067 citations

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

2002 • 1,026 citations

Large-Scale Transcriptional Activity in Chromosomes 21 and 22

2002 • 839 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 699 citations

Genome-wide detection of alternative splicing in expressed sequences of human genes

2001 • 688 citations

Frequent Alternative Splicing of Human Genes

1999 • 553 citations

Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22

2004 • 529 citations

Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

2003 • 524 citations

The use and analysis of microarray data

2002 • 477 citations

Gene Structure Prediction and Alternative Splicing Analysis Using Genomically Aligned ESTs

2001 • 410 citations

Genomewide Analysis of mRNA Processing in Yeast Using Splicing-Specific Microarrays

2002 • 406 citations

EST comparison indicates 38% of human mRNAs contain possible alternative splice forms

2000 • 303 citations

Stochastic yet biased expression of multiple Dscam splice variants by individual cells

2004 • 257 citations

Increase of functional diversity by alternative splicing

2003 • 233 citations

Profiling alternative splicing on fiber-optic arrays

2002 • 211 citations

Splicing graphs and EST assembly problem

2002 • 200 citations

Assessing the Impact of Alternative Splicing on Domain Interactions in the Human Proteome

2003 • 142 citations

Alternative Splicing and Programmed Cell Death

1999 • 133 citations

Predicting Splice Variant from DNA Chip Expression Data

2001 • 121 citations

Gene structure-based splice variant deconvolution using a microarry platform

2003 • 102 citations

The Multiassembly Problem: Reconstructing Multiple Transcript Isoforms From EST Fragment Mixtures

2004 • 92 citations

Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing

2003 • 85 citations