Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1–MAGE-A1 from a nonimmunized phage-Fab library

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

By-passing immunization

1991 • 1,603 citations

Making antibody fragments using phage display libraries

1991 • 1,195 citations

MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING

1998 • 1,017 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

ANTIBODY-ANTIGEN COMPLEXES

1990 • 853 citations

Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by geneMAGE-3 and presented by HLA-A1

1999 • 803 citations

A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.

1992 • 694 citations

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

1992 • 684 citations

Localization, Quantitation, and In Situ Detection of Specific Peptide–MHC Class I Complexes Using a Monoclonal Antibody

1997 • 679 citations

A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies

1999 • 527 citations

BIACORE Analysis of Histidine-Tagged Proteins Using a Chelating NTA Sensor Chip

1997 • 336 citations

Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells.

1995 • 324 citations

The physical and functional behavior of capture antibodies adsorbed on polystyrene

1992 • 315 citations

High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes

1997 • 292 citations

Tetrameric Complexes of Human Histocompatibility Leukocyte Antigen (HLA)-G Bind to Peripheral Blood Myelomonocytic Cells

1999 • 252 citations

Major Histocompatibility Complex Class II Compartments in Human and Mouse B Lymphoblasts Represent Conventional Endocytic Compartments

1997 • 233 citations

Designing and optimizing library selection strategies for generating high-affinity antibodies

1997 • 216 citations

beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.

1998 • 193 citations

A novel MHC class II epitope expressed in thymic medulla but not cortex

1989 • 175 citations

Characterization and Quantitation of Peptide–MHC Complexes Produced from Hen Egg Lysozyme Using a Monoclonal Antibody

1997 • 169 citations

Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity.

1996 • 155 citations

Identification of Five MAGE-A1 Epitopes Recognized by Cytolytic T Lymphocytes Obtained by In Vitro Stimulation with Dendritic Cells Transduced with MAGE-A1

1999 • 154 citations

Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein

1997 • 150 citations

Enhancement of cytolytic T lymphocyte precursor frequency in melanoma patients following immunization with the MAGE-1 peptide loaded antigen presenting cell-based vaccine.

1996 • 150 citations

A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

1996 • 131 citations

Antigen-unspecific B Cells and Lymphoid Dendritic Cells Both Show Extensive Surface Expression of Processed Antigen–Major Histocompatibility Complex Class II Complexes after Soluble Protein Exposure In Vivo or In Vitro

1997 • 128 citations

Monoclonal antibody detection of a major self peptide. MHC class II complex.

1992 • 127 citations

New treatment options for patients with melanoma: review of melanoma-derived T-cell epitope-based peptide vaccines

1996 • 105 citations

Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells

1997 • 96 citations

Expression of HLA class I molecules in human first trimester and term placenta trophoblast

1996 • 93 citations

Immunomodulation of experimental allergic encephalomyelitis by antibodies to the antigen–Ia complex

1991 • 92 citations

Reduced membrane major histocompatibility complex class I density and stability in a subset of human renal cell carcinomas with low TAP and LMP expression.

1996 • 92 citations

Cytolysis of tumor cells expressing the Neu/erbB-2, erbB-3, and erbB-4 receptors by genetically targeted naive T lymphocytes.

1996 • 76 citations

Correctly Folded T-cell Receptor Fragments in the Periplasm of Escherichia coli

1994 • 76 citations

Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma.

1998 • 66 citations

A study of complexes of class II invariant chain peptide: Major histocompatibility complex class II molecules using a new complex‐specific monoclonal antibody

1996 • 62 citations

T-cell based cancer immunotherapy: direct or redirected tumor-cell recognition?

1994 • 56 citations

A scanning tunneling microscopy comparison of passive antibody adsorption and biotinylated antibody linkage to streptavidin on microtiter wells

1994 • 52 citations

Peptide binding to HLA-A2 and HLA-B27 isolated from Escherichia coli. Reconstitution of HLA-A2 and HLA-B27 heavy chain/beta 2-microglobulin complexes requires specific peptides.

1992 • 46 citations

The monoclonal antibody HCA2 recognises a broadly shared epitope on selected classical as well as several non-classical hla class i molecules

1998 • 44 citations

Expression of MAGE-1 and -3 genes and gene products in human hepatocellular carcinoma

1999 • 43 citations

The potential of melanoma antigen expression in cancer therapy

1999 • 40 citations

Peptide-specific killing of antigen-presenting cells by a recombinant antibody–toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity

1997 • 39 citations

Production, crystallization, and preliminary X‐ray analysis of the human MHC class Ib molecule HLA‐E

1998 • 32 citations

Refolding and Reconstitution of Functionally Active Complexes of Human Leukocyte Antigen DR2 and Myelin Basic Protein Peptide from Recombinant α and β Polypeptide Chains

1995 • 29 citations

Searching for MHC‐restricted anti‐viral antibodies: antibodies recognizing the nucleoprotein of influenza virus dominate the serological response of C57BL/6 mice to syngeneic influenza‐infected cells

1987 • 24 citations

HLA Photoaffinity Labeling Reveals Overlapping Binding of Homologous Melanoma-associated Gene Peptides by HLA-A1, HLA-A29, and HLA-B44

1996 • 24 citations

Discussion

1999 • 23 citations

Refolding of human class II major histocompatibility complex molecules isolated from Escherichia coli. Assembly of peptide-free heterodimers and increased refolding-yield in the presence of antigenic peptide.

1994 • 23 citations

Immunocytokines

1997 • 21 citations

Modulation of the immune response in multiple sclerosis: production of monoclonal antibodies specific to HLA/myelin basic protein.

1997 • 18 citations

Clinical implications of the new biology in the development of melanoma vaccines

1999 • 15 citations

Recognition of insulin on MHC-class-II-expressing L929 cells by antibody and T cells

1989 • 10 citations