A WW domain-containing Yes-associated protein (YAP) is a novel transcriptional co-activator

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 • 4,168 citations

STATs and Gene Regulation

1997 • 3,927 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

1997 • 2,784 citations

p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities

1998 • 2,061 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

1997 • 1,636 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

1997 • 1,463 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

1996 • 1,195 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

1995 • 1,089 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.

1993 • 621 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Co-activators and co-repressors in the integration of transcriptional responses

1998 • 606 citations

Two Distinct Osteoblast-Specific cis-Acting Elements Control Expression of a Mouse Osteocalcin Gene

1995 • 564 citations

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.

1995 • 556 citations

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

1998 • 535 citations

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2.

1991 • 519 citations

Molecular Cloning and Characterization of PEBP2β, the Heterodimeric Partner of a Novel Drosophila runt-Related DNA Binding Protein PEBP2α

1993 • 504 citations

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

1993 • 484 citations

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300

1997 • 428 citations

The Steroid Receptor Coactivator-1 Contains Multiple Receptor Interacting and Activation Domains That Cooperatively Enhance the Activation Function 1 (AF1) and AF2 Domains of Steroid Receptors

1998 • 421 citations

Using the two-hybrid system to detect protein-protein interactions

1993 • 414 citations

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

1996 • 397 citations

Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product.

1994 • 390 citations

The WW domain: a signalling site in dystrophin?

1994 • 380 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1995 • 342 citations

Characterization of the Mammalian YAP (Yes-associated Protein) Gene and Its Role in Defining a Novel Protein Module, the WW Domain

1995 • 326 citations

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.

1995 • 318 citations

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

1998 • 308 citations

SH3 — an abundant protein domain in search of a function

1992 • 280 citations

The WW Domain of Neural Protein FE65 Interacts with Proline-rich Motifs in Mena, the Mammalian Homolog of DrosophilaEnabled

1997 • 243 citations

Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.

1990 • 227 citations

Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

1999 • 225 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1.

1993 • 223 citations

Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ: Differences between v- and c-Jun

1990 • 212 citations

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

1997 • 208 citations

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.

1994 • 204 citations

Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit

1998 • 197 citations

Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein

1995 • 184 citations

A New Transcription Factor Family Associated with Human Leukemias

1995 • 164 citations

Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain

1995 • 160 citations

The Extracellular Signal-Regulated Kinase Pathway Phosphorylates AML1, an Acute Myeloid Leukemia Gene Product, and Potentially Regulates Its Transactivation Ability

1996 • 153 citations

Chromatin: Histone acetyltransferases in control

1997 • 139 citations

Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter.

1994 • 138 citations

MEF2B Is a Potent Transactivator Expressed in Early Myogenic Lineages

1996 • 135 citations

The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain.

1991 • 128 citations

WW domains and retrovirus budding

1996 • 124 citations

AP-2.2: A Novel AP-2-Related Transcription Factor Induced by Retinoic Acid during Differentiation of P19 Embryonal Carcinoma Cells

1996 • 115 citations

Subcellular Localization of the α and β Subunits of the Acute Myeloid Leukemia-Linked Transcription Factor PEBP2/CBF

1995 • 109 citations

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter.

1998 • 105 citations

WWP, a New Amino Acid Motif Present in Single or Multiple Copies in Various Proteins Including Dystrophin and the SH3-Binding Yes-Associated Protein YAP65

1994 • 98 citations

Functional Dissection of the α and β Subunits of Transcription Factor PEBP2 and the Redox Susceptibility of Its DNA Binding Activity

1996 • 97 citations

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements.

1992 • 93 citations

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

1997 • 82 citations

A Novel Transcript Encoding an N-Terminally Truncated AML1/PEBP2αB Protein Interferes with Transactivation and Blocks Granulocytic Differentiation of 32Dcl3 Myeloid Cells

1997 • 79 citations

Using Molecular Repertoires to Identify High-Affinity Peptide Ligands of the WW Domain of Human and Mouse YAP

1997 • 66 citations

Physical and Functional Interactions between the Transactivation Domain of the Hematopoietic Transcription Factor NF-E2 and WW Domains

1998 • 66 citations

A Novel Repression Module, an Extensive Activation Domain, and a Bipartite Nuclear Localization Signal Defined in the Immediate-Early Transcription Factor Egr-1

1993 • 66 citations

The rsp5-domain is shared by proteins of diverse functions

1995 • 63 citations

Structure and function of SH2 domains

1994 • 63 citations

Scratching the surface with the PH domain

1995 • 62 citations

Interaction of WW Domains with Hematopoietic Transcription Factor p45/NF-E2 and RNA Polymerase II

1997 • 62 citations

AML1 Is Expressed in Skeletal Muscle and Is Regulated by Innervation

1994 • 55 citations

AML1 is expressed in skeletal muscle and is regulated by innervation.

1994 • 49 citations

Mapping functional regions of the segment-specific transcription factor Krox-20

1992 • 46 citations

WW (WWP) Domains: From Structure to Function

1998 • 45 citations

The Runt Domain Transcription Factor, PEBP2/CBF, and its Involvement in Human Leukemia

1997 • 42 citations

HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity.

1991 • 37 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 37 citations

The cDNA cloning of the transcripts of human PEBP2αA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia

1997 • 35 citations

Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia

1996 • 27 citations

Stimulation of polyomavirus DNA replication by wild-type p53 through the DNA-binding site.

1994 • 27 citations

Stimulation of Polyomavirus DNA Replication by Wild-Type p53 Through the DNA-Binding Site

1994 • 11 citations

The runt protein and its companion PEBP2: a close link between this transcription factor and AML.

1997 • 9 citations