p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1992 • 4,648 citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 • 4,043 citations

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

1990 • 2,587 citations

A model for p53-induced apoptosis

1997 • 2,502 citations

p53: puzzle and paradigm.

1996 • 2,363 citations

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1996 • 2,304 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Amplification of a gene encoding a p53-associated protein in human sarcomas

1992 • 1,959 citations

p53 function and dysfunction

1992 • 1,918 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

1997 • 1,636 citations

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1993 • 1,445 citations

Soft-Tissue Sarcomas, Breast Cancer, and Other Neoplasms

1969 • 1,437 citations

p73 is a human p53-related protein that can induce apoptosis

1997 • 951 citations

Oncogenic forms of p53 inhibit p53-regulated gene expression

1992 • 933 citations

A p53-Dependent Mouse Spindle Checkpoint

1995 • 668 citations

Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

1994 • 587 citations

Kinetochore Localization of Murine Bub1 Is Required for Normal Mitotic Timing and Checkpoint Response to Spindle Damage

1997 • 543 citations

Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix.

1996 • 470 citations

Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase

1993 • 456 citations

A comparison of the biological activities of wild‐type and mutant p53

1993 • 423 citations

Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression

1992 • 333 citations

Clonal p53 mutation in primary cervical cancer: association with human-papillomavirus-negative tumours

1992 • 313 citations

Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma

1994 • 302 citations

A novel protein with strong homology to the tumor suppressor p53

1997 • 282 citations

Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma

1994 • 261 citations

An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

1998 • 241 citations

Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression.

1989 • 220 citations

Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas.

1996 • 170 citations

Relationship of p53 to the control of apoptotic cell death.

1994 • 163 citations

Evidence for two tumour suppressor loci on chromosomal bands 1p35–36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification

1995 • 143 citations

Distal deletion of chromosome Ip in ductal carcinoma of the breast.

1989 • 135 citations

DNA gains in 3q occur frequently in squamous cell carcinoma of the lung, but not in adenocarcinoma

1998 • 130 citations

Lonely No More: p53 Finds Its Kin in a Tumor Suppressor Haven

1997 • 83 citations

Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16.

1994 • 73 citations

Epidermal Differentiation and Squamous Metaplasia: From Stem Cell to Cell Death

1997 • 45 citations

Changes in Biomarker Expression in the Development of Prostatic Adenocarcinoma

1997 • 26 citations