Characterization of the Mammalian YAP (Yes-associated Protein) Gene and Its Role in Defining a Novel Protein Module, the WW Domain

Basic local alignment search tool

1990 • 87,358 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Current protocols in molecular biology

1988 • 2,473 citations

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1993 • 2,329 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

Combining evolutionary information and neural networks to predict protein secondary structure

1994 • 1,471 citations

Profile analysis: detection of distantly related proteins.

1987 • 1,308 citations

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1993 • 1,026 citations

Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma

1988 • 1,022 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1993 • 972 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

SH2 and SH3 domains

1993 • 697 citations

The structural and functional diversity of dystrophin

1993 • 632 citations

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1992 • 603 citations

Identification of a Protein that Binds to the SH3 Region of Abl and Is Similar to Bcr and GAP-rho

1992 • 553 citations

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

1992 • 537 citations

Crystal structure of a Src-homology 3 (SH3) domain

1992 • 474 citations

Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product.

1994 • 390 citations

The WW domain: a signalling site in dystrophin?

1994 • 380 citations

Signalling through SH2 and SH3 domains

1993 • 355 citations

Solution Structure of the SH3 Domain of Src and Identification of Its Ligand-Binding Site

1992 • 334 citations

MKK1 and MKK2, Which Encode Saccharomyces cerevisiae Mitogen-Activated Protein Kinase-Kinase Homologs, Function in the Pathway Mediated by Protein Kinase C

1993 • 306 citations

Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.

1990 • 296 citations

Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks.

1994 • 286 citations

SH3 — an abundant protein domain in search of a function

1992 • 280 citations

The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.

1991 • 224 citations

Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells

1993 • 222 citations

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.

1992 • 217 citations

Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin.

1993 • 208 citations

Increasing complexity of the dystrophin-associated protein complex.

1994 • 194 citations

Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin.

1993 • 194 citations

Solution structure and ligand-binding site of the SH3 domain of the p85α subunit of phosphatidylinositol 3-kinase

1993 • 185 citations

The v-Src SH3 domain binds phosphatidylinositol 3'-kinase.

1993 • 180 citations

Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src.

1992 • 179 citations

Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src.

1991 • 175 citations

Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

1990 • 174 citations

Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein.

1986 • 171 citations

Structure and function of the SH3 domain

1994 • 168 citations

Searching for the 1 in 2,400,000: A review of dystrophin gene point mutations

1994 • 159 citations

Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.

1990 • 151 citations

Structure of the Pl3K SH3 domain and analysis of the SH3 family

1993 • 137 citations

Shuffled domains in extracellular proteins

1991 • 133 citations

Solution structure of the SH3 domain of phospholipase C-?

1993 • 117 citations

Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11.

1989 • 112 citations

Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning

1990 • 106 citations

The chicken dystrophin cDNA: striking conservation of the C-terminal coding and 3′ untranslated regions between man and chicken.

1988 • 106 citations

Yeast chromosome III: new gene functions.

1994 • 104 citations

Closing in on SH2 specificity

1993 • 86 citations

Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95.

1988 • 85 citations

Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.

1991 • 75 citations

The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.

1986 • 71 citations

A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease loci.

1991 • 67 citations

An efficient directional cloning system to construct cDNA libraries containing full-length inserts at high frequency

1989 • 66 citations

Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein.

1989 • 62 citations

Fine-scale mapping of the gene responsible for multiple endocrine neoplasia type 1 (MEN 1).

1992 • 43 citations

Molecular Basis of Human Cancer

1991 • 33 citations

A fast, sensitive pattern-matching approach for protein sequences

1993 • 27 citations

Characterization of human bone marrow‐derived closed circular DNA clones

1993 • 7 citations

Deleted Work

1955 • 0 citations