Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

1997 • 2,784 citations

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

1997 • 2,050 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

The Atlas of Mouse Development

1992 • 1,782 citations

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

1997 • 1,463 citations

Adipogenesis and Obesity: Rounding Out the Big Picture

1996 • 1,268 citations

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.

1994 • 1,138 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Bone and haematopoietic defects in mice lacking c-fos

1992 • 939 citations

Connective Tissue and Its Heritable Disorders

2002 • 930 citations

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

1992 • 643 citations

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.

1993 • 621 citations

Two Distinct Osteoblast-Specific cis-Acting Elements Control Expression of a Mouse Osteocalcin Gene

1995 • 564 citations

A transcriptional hierarchy involved in mammalian cell-type specification

1992 • 428 citations

Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors.

1996 • 420 citations

The runt domain identifies a new family of heterometric transcriptional regulators

1993 • 331 citations

Development of adynamic bone in patients with secondary hyperparathyroidism after intermittent calcitriol therapy

1994 • 316 citations

The Tissue-Specific Nuclear Matrix Protein, NMP-2, Is a Member of the AML/PEBP2/Runt Domain Transcription Factor Family: Interactions with the Osteocalcin Gene Promoter

1995 • 245 citations

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

1993 • 229 citations

A PEBP2α/AML-1-related Factor Increases Osteocalcin Promoter Activity through Its Binding to an Osteoblast-specific cis-Acting Element

1995 • 171 citations

A New Transcription Factor Family Associated with Human Leukemias

1995 • 164 citations

Expression of the Runt Domain-Encoding PEBP2α Genes in T cells during Thymic Development

1995 • 160 citations

Limbs: a model for pattern formation within the vertebrate body plan

1996 • 155 citations

Genetic mapping of cleidocranial dysplasia and evidence of a microdeletion in one family

1995 • 116 citations

1,25-Dihydroxyvitamin D3 Inhibits Osteocalcin Expression in Mouse through an Indirect Mechanism

1997 • 113 citations

Region-specific expression in early chick and mouse embryos of Ghox-lab and Hox 1.6, vertebrate homeobox-containing genes related to Drosophila labial

1990 • 108 citations

The localized requirements for a gene affecting segmentation in Drosophila: Analysis of larvae mosaic for runt

1985 • 106 citations

Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice

1994 • 104 citations

Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts.

1996 • 103 citations

Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs.

1994 • 98 citations

Expression of runt in the mouse embryo

1995 • 77 citations

Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter

1995 • 47 citations

Regulation of COL1A1 expression in type I collagen producing tissues: Identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice

1995 • 45 citations

A ubiquitous repressor interacting with an F9 cell-specific silencer and its functional suppression by differentiated cell-specific positive factors.

1990 • 44 citations

Animal model: Skeletal anomalies in mice with cleidocranial dysplasia

1987 • 43 citations

Identification of the mouse pro-α1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts

1996 • 34 citations

Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs

1994 • 30 citations

Identification of a minimal sequence of the mouse Pro-α1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts

1996 • 9 citations