Radiation induced apoptosis

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

1993 • 2,484 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

Oxidative stress as a mediator of apoptosis

1994 • 2,210 citations

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1995 • 1,892 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

Phagocyte recognition of cells undergoing apoptosis

1993 • 1,000 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 898 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo.

1995 • 537 citations

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1993 • 481 citations

Macrophage recognition of cells undergoing programmed cell death (apoptosis).

1985 • 460 citations

Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation.

1993 • 419 citations

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1995 • 409 citations

Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines.

1994 • 372 citations

Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin‐1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation

1993 • 351 citations

The sensitivity of lymphocytes to ionising radiation

1952 • 289 citations

Glutamate triggers internucleosomal DNA cleavage in neuronal cells

1991 • 276 citations

Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7.

1995 • 272 citations

Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells

1985 • 271 citations

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells.

1991 • 201 citations

Interleukin-1β-Induced Nitric Oxide Production Activates Apoptosis in Pancreatic RINm5F Cells

1994 • 194 citations

Inhibition of apoptosis as a mechanism of tumor promotion

1994 • 192 citations

Increased Activity of L-Type Ca ²⁺ Channels Exposed to Serum from Patients with Type I Diabetes

1993 • 188 citations

Nuclear calcium transport and the role of calcium in apoptosis

1994 • 178 citations

Androgens induce resistance to bcl-2-mediated apoptosis in LNCaP prostate cancer cells.

1995 • 154 citations

Molecular controls of apoptosis: differentiation/growth arrest primary response genes, proto-oncogenes, and tumor suppressor genes as positive & negative modulators.

1994 • 153 citations

Saturable Repair Models of Radiation Action in Mammalian Cells

1985 • 150 citations

Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-(α is mediated by lipoxygenase metabolites of arachidonic acid

1992 • 132 citations

Ionizing Radiation-induced Cell Death

1994 • 119 citations

Radiation Response of Mouse Lymphoid and Myeloid Cell Lines. Part III. Different Signals Can Lead to Apoptosis and May Influence Sensitivity to Killing by DNA Double-strand Breakage

1994 • 117 citations

Radiation Response of Mouse Lymphoid and Myeloid Cell Lines. Part II. Apoptotic Death is Shown by all Lines Examined

1994 • 111 citations

Formation of 50 kbp chromatin fragments in isolated liver nuclei is mediated by protease and endonuclease activation

1994 • 96 citations

Activation of mouse lymphocytes inhibits induction of rapid cell death by x-irradiation.

1985 • 71 citations

Radioresistance of Phytohemagglutinin-Treated Normal and Leukemic Lymphocytes<xref ref-type="fn" rid="FN2">2</xref>

1964 • 71 citations

Increasing the susceptibility of the rat 208F fibroblast cell line to radiation-induced apoptosis does not alter its clonogenic survival dose-response

1995 • 68 citations

The Effect of Low-dose Irradiation on Unstimulated and PHA-stimulated Human Lymphocyte Subsets

1988 • 61 citations

Initial Damage or Repair as the Major Determinant of Cellular Radiosensitivity?

1989 • 55 citations

DNA damage induced in human diploid cells by decay of incorporated radionuclides.

1984 • 52 citations

Radiation Response of Mouse Lymphoid and Myeloid Cell Lines. Part I. Sensitivity to Killing by Ionizing Radiation, Rate of Loss of Viability, and Cell Type of Origin

1994 • 49 citations

Control of cell death (apoptosis) by diethylstilbestrol in an estrogen-dependent kidney tumor

1991 • 48 citations

Ca(2+)-regulated serine protease associated with the nuclear scaffold.

1992 • 45 citations

On the Measurement of DNA Double-Strand Breaks by Neutral Elution

1989 • 38 citations

P53 Status, DNA Double-strand Break Repair Proficiency, and Radiation Response of Mouse Lymphoid and Myeloid Cell Lines

1994 • 37 citations

Effect of Ploidy on the Response of V79 Cells to Ionizing Radiation

1987 • 25 citations

Ion Signalling in Apoptosis

1994 • 25 citations

Primary and secondary vacuoles in thymic cells exposed in vitro to x-rays

1947 • 21 citations

Phorbol Esters Can Protect Mouse Pre-T Cell Lines from Radiation-induced Rapid Interphase Apoptosis

1994 • 21 citations

The biological basis of radiotherapy. Second edition

1989 • 4 citations

Deleted Work

1955 • 0 citations