Ca(2+)-regulated serine protease associated with the nuclear scaffold.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

1979 • 1,648 citations

Esters of Methanesulfonic Acid as Irreversible Inhibitors of Acetylcholinesterase

1962 • 1,510 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

The nuclear lamina is a meshwork of intermediate-type filaments

1986 • 957 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase

1990 • 783 citations

cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

1986 • 711 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1990 • 642 citations

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

1990 • 464 citations

Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C

1990 • 425 citations

Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival.

1991 • 421 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

1990 • 377 citations

On the occurrence of a fibrous lamina on the inner aspect of the nuclear envelope in certain cells of vertebrates

1966 • 366 citations

Lamin B constitutes an intermediate filament attachment site at the nuclear envelope.

1987 • 306 citations

Abnormally high expression of proteasomes in human leukemic cells.

1990 • 305 citations

[7] Purification and properties of NADPH-Cytochrome P-450 reductase

1978 • 303 citations

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

1989 • 277 citations

Active involvement of Ca2+ in mitotic progression of Swiss 3T3 fibroblasts.

1990 • 183 citations

Changes in expressions of proteasome and ubiquitin genes in human renal cancer cells.

1991 • 168 citations

The ATP-dependent Clp protease of Escherichia coli. Sequence of clpA and identification of a Clp-specific substrate.

1990 • 156 citations

Escherichia coli contains a soluble ATP-dependent protease (Ti) distinct from protease La.

1987 • 142 citations

Nuclear lamin LI of Xenopus laevis: cDNA cloning, amino acid sequence and binding specificity of a member of the lamin B subfamily.

1987 • 141 citations

Possible mechanism of nuclear translocation of proteasomes

1990 • 132 citations

Isolation and sequence of a rat chymotrypsin B gene.

1984 • 128 citations

The Drosophila proteasome undergoes changes in its subunit pattern during development

1989 • 127 citations

Mitotic control by metaphase-promoting factor and Cdc proteins

1989 • 126 citations

Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes.

1989 • 121 citations

Internuclear exchange of an inner nuclear membrane protein (p55) in heterokaryons: in vivo evidence for the interaction of p55 with the nuclear lamina.

1990 • 112 citations

Calcium restriction prolongs metaphase in dividing Tradescantia stamen hair cells.

1985 • 107 citations

A new lamin in Xenopus somatic tissues displays strong homology to human lamin A.

1987 • 106 citations

Purification and characterization of major extracellular proteinases from Trichophyton rubrum

1985 • 105 citations

Role of protein synthesis and proteases in production and inactivation of maturation-promoting activity during meiotic maturation of starfish oocytes

1985 • 104 citations

Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells.

1986 • 103 citations

Molecular cloning and functional analysis of three subunits of yeast proteasome.

1991 • 97 citations

Intracellular levels and distribution of Ca2+ in digitonin-permeabilized cells

1985 • 97 citations

Establishment of a transplantable ascites variant of a rat hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene.

1970 • 91 citations

Pertinence of nuclear envelope nucleoside triphosphatase activity to ribonucleic acid transport

1980 • 90 citations

The PROS-35 gene encodes the 35 kd protein subunit of Drosophila melanogaster proteasome.

1989 • 89 citations

Molecular cloning of cDNA for proteasomes (multicatalytic proteinase complexes) from rat liver: primary structure of the largest component (C2)

1989 • 86 citations

Molecular cloning of cDNA for proteasomes from rat liver: primary structure of component C3 with a possible tyrosine phosphorylation site

1990 • 73 citations

Direct evidence for nuclear and cytoplasmic colocalization of proteasomes (Multiprotease complexes) in liver

1989 • 69 citations

Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome)

1990 • 67 citations

cDNA cloning and sequencing of component C9 of proteasomes from rat hepatoma cells

1990 • 67 citations

Sea urchin prosome: characterization and changes during development.

1987 • 59 citations

Submicromolar Ca2+ regulates phosphorylating respiration by normal rat liver and AS-30D hepatoma mitochondria by different mechanisms.

1990 • 55 citations

Proteolytic Activity Associated with the Nuclear Scaffold

1989 • 50 citations

An ATP‐dependent protease and ingensin, the multicatalytic proteinase, in K562 cells

1988 • 49 citations

Separation of yeast proteasome subunits

1989 • 40 citations

Nucleotide sequence of the full-length mouse lamin C cDNA and its deduced amino-acid sequence

1989 • 39 citations

Characterization of an ATPase on the Inside of Rat‐Liver Nuclear Envelopes by Affinity Labeling

1982 • 39 citations

Rigidity of the nucleus during nuclear rotation in 3T3 cells*1

1988 • 31 citations

Differential sensitivity of vimentin and nuclear lamins from Ehrlich ascites tumor cells toward Ca2+ -activated neutral thiol proteinase.

1988 • 26 citations

Complete primary structure of a calcium‐dependent serine proteinase capable of degrading extracellular matrix proteins

1989 • 25 citations

Fluorescent measurements of intracellular free calcium in isolated toad urinary bladder epithelial cells

1987 • 25 citations

The 46-kDa nucleoside triphosphatase of rat liver nuclear scaffold represents the N-terminal portion of lamins A/C

1988 • 21 citations

Regulation of nuclear scaffold protease activity by calcium

1990 • 19 citations

Purification and characterization of a novel calcium-dependent serine proteinase secreted from malignant hamster embryo fibroblast Nil2C2

1989 • 17 citations

Lens neutral endopeptidase occurs in other bovine and human tissues

1987 • 16 citations

The Mr 46,000 nuclear scaffold ATP-binding protein: identification of the putative nucleoside triphosphatase by proteolysis and monoclonal antibodies directed against lamins A/C.

1990 • 13 citations

Alterations in nuclear scaffold constituents during carbon tetrachloride–induced liver regeneration

1991 • 7 citations

PREPARATION OF LYSOSOME-RICH FRACTIONS WITH OR WITHOUT PEROXISOMES

1972 • 6 citations

Induction of a Novel Ca 2+-Dependent Chymotrypsin-Like Serine Protease by Tumor Promoters in Rat Livers<xref ref-type="fn" rid="FN1">2</xref>

1986 • 6 citations