Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-(α is mediated by lipoxygenase metabolites of arachidonic acid

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[1] Role of free radicals and catalytic metal ions in human disease: An overview

1990 • 5,041 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Induction of Manganous Superoxide Dismutase by Tumor Necrosis Factor: Possible Protective Mechanism

1988 • 933 citations

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

1989 • 821 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1987 • 640 citations

Cytotoxic mechanism of tumor necrosis factor‐α

1990 • 539 citations

A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia

1985 • 525 citations

G-protein βγ-subunits activate the cardiac muscarinic K+-channel via phospholipase A2

1989 • 438 citations

New Aspects of the Mode of Action of Nonsteroid Anti-Inflammatory Drugs

1974 • 427 citations

Two Different Cell Types have Different Major Receptors for Human Tumor Necrosis Factor (TNFα)

1989 • 368 citations

MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.

1990 • 319 citations

Arachidonic acid metabolites as intracellular modulators of the G protein-gated cardiac K+ channel

1989 • 299 citations

Tumour cell killing by tumour necrosis factor: inhibition by anaerobic conditions, free-radical scavengers and inhibitors of arachidonate metabolism.

1987 • 206 citations

Analysis of gene expression during differentiation of adipogenic cells in culture and hormonal control of the developmental program.

1984 • 203 citations

Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production

1992 • 179 citations

TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metabolite.

1991 • 159 citations

Involvement of phospholipase A2 activation in tumour cell killing by tumour necrosis factor.

1988 • 124 citations

Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells.

1988 • 101 citations

Human Mn superoxide dismutase cDNA sequence

1987 • 91 citations

Evidence for two mechanisms by which tumor necrosis factor kills cells

1989 • 80 citations

Modulation of tumor necrosis factor-α cytotoxicity in L929 cells by bacterial toxins, hydrocortisone and inhibitors of arachidonic acid metabolism

1987 • 60 citations

Resistance to killing by tumor necrosis factor in an adipocyte cell line caused by a defect in arachidonic acid biosynthesis.

1991 • 57 citations

Free radicals in immunological killing: The case of tumour necrotising factor (TNF)

1986 • 19 citations