Improvement in endothelial function by angiotensin-converting enzyme inhibition in non–insulin-dependent diabetes mellitus

The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy

1993 • 5,296 citations

Role of Oxidative Stress in Development of Complications in Diabetes

1991 • 3,774 citations

Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications

1988 • 2,527 citations

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

1996 • 2,456 citations

Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency

1996 • 1,759 citations

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance.

1996 • 1,695 citations

Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.

1993 • 1,542 citations

Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

1994 • 1,326 citations

Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction

1994 • 1,240 citations

Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

1991 • 1,161 citations

Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

1993 • 1,102 citations

Angiotensin-Converting Enzyme Inhibition With Quinapril Improves Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

1996 • 1,065 citations

Cellular and molecular mechanisms of endothelial cell dysfunction.

1997 • 1,064 citations

Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus

1996 • 1,024 citations

Simvastatin, an HMG–Coenzyme A Reductase Inhibitor, Improves Endothelial Function Within 1 Month

1997 • 968 citations

Impaired endothelium-dependent and independent vasodilation in patients with Type 2 (non-insulin-dependent) diabetes mellitus

1992 • 922 citations

Passive Smoking and Impaired Endothelium-Dependent Arterial Dilatation in Healthy Young Adults

1996 • 907 citations

Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.

1996 • 884 citations

Nitric oxide release accounts for insulin's vascular effects in humans.

1994 • 747 citations

Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells.

1996 • 735 citations

Ascorbic Acid Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

1996 • 593 citations

Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

1997 • 585 citations

Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes.

1992 • 527 citations

Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. European Microalbuminuria Captopril Study Group

1994 • 494 citations

Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia

1992 • 475 citations

Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis

1994 • 457 citations

Impairment of Coronary Vascular Reserve and ACh-Induced Coronary Vasodilation in Diabetic Patients With Angiographically Normal Coronary Arteries and Normal Left Ventricular Systolic Function

1993 • 443 citations

Measuring Forearm Blood Flow and Interpreting the Responses to Drugs and Mediators

1995 • 402 citations

Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta.

1990 • 375 citations

Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal.

1992 • 343 citations

Endothelial Nitric Oxide Production and Insulin Sensitivity

1996 • 323 citations

The beneficial effect of angiotensin-converting enzyme inhibition with captopril on diabetic nephropathy in normotensive IDDM patients with microalbuminuria

1995 • 278 citations

Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway.

1994 • 254 citations

Acute Amelioration of Diabetic Endothelial Dysfunction with a Derivative of the Nitric Oxide Synthase Cofactor, Tetrahydrobiopterin

1997 • 224 citations

Improvement in endothelial function by angiotensin converting enzyme inhibition in insulin-dependent diabetes mellitus.

1997 • 220 citations

Inhibition of Nitric Oxide Synthesis in Forearm Vasculature of Insulin-Dependent Diabetic Patients: Blunted Vasoconstriction in Patients with Microalbuminuria

1993 • 214 citations

Impaired Endothelium-Dependent and Independent Dilatation of Forearm Resistance Arteries in Men with Diet-Treated Non-Insulin-Dependent Diabetes: Role of Dyslipidaemia

1996 • 204 citations

Dietary fish oil augments nitric oxide production or release in patients with Type 2 (non-insulin-dependent) diabetes mellitus

1993 • 201 citations

Effect of Insulin on Acetylcholine-Induced Vasodilation in Normotensive Subjects and Patients With Essential Hypertension

1995 • 193 citations

Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.

1992 • 175 citations

Kinins mediate the antiproliferative effect of ramipril in rat carotid artery

1992 • 144 citations

Endothelium-Derived Relaxing Factors and Converting Enzyme Inhibition

1995 • 129 citations

Angiotensin-Converting Enzyme Inhibition Restores Flow-Dependent and Cold Pressor Test–Induced Dilations in Coronary Arteries of Hypertensive Patients

1996 • 129 citations

Endothelium-Dependent Vascular Relaxation in Patients With Type I Diabetes

1993 • 124 citations

Early endothelial dysfunction in adults at risk from atherosclerosis: different responses to l-arginine

1998 • 112 citations

Endothelium-derived nitric oxide activity in forearm vessels of tennis players

1996 • 103 citations

Forearm Nitric Oxide Balance, Vascular Relaxation, and Glucose Metabolism in NIDDM Patients

1997 • 92 citations

Effect of angiotensin-converting enzyme inhibitors on endothelium-dependent peripheral vasodilation in patients with chronic heart failure

1994 • 89 citations

Improved Insulin Action and Glycemic Control After Long Term Angiotensin-Converting Enzyme Inhibition in Subjects with Arterial Hypertension and Type II Diabetes

1993 • 86 citations

Effect of Chronic Angiotensin-Converting Enzyme Inhibition on Endothelial Function in Patients with Chronic Heart Failure

1995 • 85 citations

Bradykinin-Induced Vasodilation of Human Coronary Arteries In Vivo: Role of Nitric Oxide and Angiotensin-Converting Enzyme

1997 • 84 citations

Effect of Enalapril on Endothelial Function in Young Insulin-Dependent Diabetic Patients: A Randomized, Double-Blind Study 11This study was supported by a grant from Merck Sharp and Dohme Ltd., Hertfordshire, England, United Kingdom. Ms. Donald is supported by a grant from the Coronary Artery Disease Research Foundation (CORDA), London, England, United Kingdom.

1998 • 80 citations

Vascular responsiveness and cation exchange in insulin-dependent diabetes

1991 • 74 citations

THERAPEUTIC RESTORATION OF ENDOTHELIAL FUNCTION IN HYPERCHOLESTEROLAEMIC SUBJECTS: EFFECT OF FISH OILS

1994 • 61 citations

Angiotensin Converting Enzyme Inhibitors as Oxygen Free Radical Scavengers

1993 • 58 citations

Endothelium-Dependent Vasodilation is Augmented by Angiotensin Converting Enzyme Inhibitors in Healthy Volunteers

1992 • 57 citations

Perindopril inhibits both the development of atherosclerosis in the cholesterol-fed rabbit and lipoprotein binding to smooth muscle cells in culture

1994 • 43 citations

Effect of Long-Term Angiotensin-Converting Enzyme Inhibition on Endothelial Function in Patients with the Insulin-Resistance Syndrome

1995 • 41 citations

Captopril scavenges hydrogen peroxide and reduces, but does not eliminate, oxidant-induced cell injury

1993 • 39 citations

Vascular action of the hypoglycaemic agent gliclazide in diabetic rabbits

1998 • 37 citations

Tetrahydrobiopterin metabolism in the streptozotocin induced diabetic state in rats

1989 • 34 citations

Lisinopril improves endothelial dysfunction in hypertensive NIDDM subjects with diabetic nephropathy

1997 • 32 citations

Endothelium-mediated vasodilation during ACE inhibition

1995 • 25 citations

Lack of Effect of Vitamin E Administration on Basal Nitric Oxide Function in Male Smokers and Non-Smokers

1995 • 23 citations

The effect of angiotensin‐converting enzyme inhibitors on human neutrophil chemotaxis in vitro.

1994 • 10 citations

Comparison of the Free Radical-scavenging Ability of Captopril and Ascorbic Acid in an In-vitro Model of Lipid Oxidation. Implications for Reperfusion Injury and ACE Inhibitor Therapy

1994 • 9 citations

The HMG-CoA reductase inhibitor, simvastatin, improves endothelial function within one month

1997 • 7 citations

Protective effects of cilazapril against free radical injury in myocardial ischaemia-reperfusion

1995 • 7 citations