Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)

1988 • 3,818 citations

Effect of Enalapril on Mortality and the Development of Heart Failure in Asymptomatic Patients with Reduced Left Ventricular Ejection Fractions

1992 • 3,708 citations

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Hypercholesterolemia increases endothelial superoxide anion production.

1993 • 1,799 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.

1993 • 1,240 citations

Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.

1988 • 1,077 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

1995 • 737 citations

Association of the Renin-Sodium Profile with the Risk of Myocardial Infarction in Patients with Hypertension

1991 • 734 citations

Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.

1995 • 660 citations

Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.

1989 • 558 citations

NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium

1994 • 546 citations

Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells.

1996 • 513 citations

Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

1989 • 467 citations

Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits.

1991 • 403 citations

Angiotensin II Induces c-fos mRNA in Aortic Smooth Muscle

1989 • 401 citations

Free radicals in diabetic endothelial cell dysfunction

1994 • 398 citations

An NADPH oxidase superoxide-generating system in the rabbit aorta

1995 • 295 citations

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

1994 • 286 citations

Coronary Kinin Generation Mediates Nitric Oxide Release After Angiotensin Receptor Stimulation

1995 • 259 citations

Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat.

1994 • 225 citations

Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals

1994 • 198 citations

Dietary Correction of Hypercholesterolemia in the Rabbit Normalizes Endothelial Superoxide Anion Production

1995 • 197 citations

Angiotensin receptor regulates cardiac hypertrophy and transforming growth factor-beta 1 expression.

1994 • 196 citations

Kinetics of Cytochrome C2+ Oxidation by Peroxynitrite: Implications for Superoxide Measurements in Nitric Oxide-Producing Biological-Systems

1995 • 188 citations

Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle

1994 • 165 citations

Induction of the proto-oncogene c-jun by angiotensin II.

1990 • 143 citations

Properties of a superoxide anion-generating microsomal NADH oxidoreductase, a potential pulmonary artery PO2 sensor

1994 • 127 citations

Tissue renin-angiotensin systems. Their role in cardiovascular disease.

1993 • 125 citations

Arachidonic acid acts as an intracellular activator of NADPH-oxidase in Fc gamma receptor-mediated superoxide generation in macrophages.

1987 • 98 citations

Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes

1993 • 74 citations

Role of prostanoids in renin-dependent and renin-independent hypertension.

1991 • 63 citations

Angiotensin II alters aortic fibronectin independently of hypertension.

1994 • 48 citations

Angiotensin II and structural remodeling of coronary vessels in rats.

1994 • 44 citations

Nitric oxide in the pathogenesis of hypertension

1995 • 33 citations

Membrane-associated diacylglycerol kinase activity is increased by noradrenaline, but not by angiotensin II, in arterial smooth muscle

1994 • 27 citations

Mechanisms of cardiac growth. The role of the renin-angiotensin system

1992 • 18 citations

Induction of the Proto-Oncogene c-jun by Angiotensin II

1990 • 17 citations

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