Angiotensin-Converting Enzyme Inhibition Restores Flow-Dependent and Cold Pressor Test–Induced Dilations in Coronary Arteries of Hypertensive Patients

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.

1977 • 4,520 citations

Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension

1990 • 2,388 citations

Role of endothelium in responses of vascular smooth muscle.

1983 • 1,975 citations

Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo

1995 • 1,632 citations

Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension.

1990 • 803 citations

Endothelium‐dependent hyperpolarization of canine coronary smooth muscle

1988 • 785 citations

Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test.

1988 • 564 citations

Vasodilation to acetylcholine in primary and secondary forms of human hypertension.

1993 • 550 citations

A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin

1970 • 533 citations

Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis.

1991 • 531 citations

Comparative assessment of stimuli that release neuronal and adrenomedullary catecholamines in man.

1979 • 460 citations

Endothelium-dependent, flow-induced dilation of isolated coronary arterioles

1990 • 420 citations

Endothelium-derived contracting factors.

1992 • 395 citations

Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels.

1993 • 395 citations

Intracoronary papaverine: an ideal coronary vasodilator for studies of the coronary circulation in conscious humans.

1986 • 383 citations

Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition.

1984 • 367 citations

Coronary vasomotion in response to sympathetic stimulation in humans: Importance of the functional integrity of the endothelium

1989 • 346 citations

Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal.

1992 • 343 citations

Flow-dependent coronary artery dilatation in humans.

1989 • 333 citations

Preserved Endothelium-Dependent Vasodilatation in Patients with Essential Hypertension

1994 • 287 citations

Flow-Dependent, Endothelium-Mediated Dilation of Epicardial Coronary Arteries in Conscious Dogs

1984 • 279 citations

Interaction Between Sympathetic and Renin-angiotensin System

1984 • 249 citations

Effect of antihypertensive treatment on endothelium-dependent vascular relaxation in patients with essential hypertension

1993 • 246 citations

Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension

1992 • 238 citations

Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats.

1990 • 234 citations

Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries.

1993 • 233 citations

Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin I converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxing and hyperpolarizing factors.

1992 • 221 citations

Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines.

1992 • 214 citations

Role of Endogenous Bradykinin in Human Coronary Vasomotor Control

1995 • 207 citations

Antihypertensive treatment normalizes decreased endothelium-dependent relaxations in rats with salt-induced hypertension.

1987 • 196 citations

Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats.

1988 • 193 citations

Effect of captopril and enalapril on endothelial function in hypertensive patients.

1994 • 186 citations

Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.

1992 • 175 citations

Epicardial coronary artery responses to acetylcholine are impaired in hypertensive patients.

1992 • 173 citations

Abnormal endothelium-dependent coronary vasomotion in hypertensive patients

1992 • 165 citations

Endothelium-dependent responses in carotid and renal arteries of normotensive and hypertensive rats.

1988 • 157 citations

Antihypertensive therapy augments endothelium-dependent relaxations in coronary arteries of spontaneously hypertensive rats.

1994 • 134 citations

Direct myocardial and coronary effects of enalaprilat in patients with dilated cardiomyopathy: assessment by a bilateral intracoronary infusion technique.

1988 • 115 citations

ACE inhibition attenuates sympathetic coronary vasoconstriction in patients with coronary artery disease.

1992 • 93 citations

Flow-mediated vasodilation of human epicardial coronary arteries: effect of inhibition of nitric oxide synthesis

1996 • 89 citations

Nitric oxide modulates coronary autoregulation in the guinea pig.

1992 • 86 citations

Loss of Flow-Dependent Coronary Artery Dilatation in Patients With Hypertension

1995 • 86 citations

Regulation of large coronary arteries by increases in myocardial metabolic demands in conscious dogs.

1981 • 76 citations

Assessment of airways, tremor and chronotropic responses to inhaled salbutamol in the quantification of beta 2‐adrenoceptor blockade.

1989 • 70 citations

Effects of the converting enzyme inhibitor cilazaprilat on endothelium-dependent responses.

1991 • 69 citations

Coronary artery constriction caused by the cold pressor test in human hypertension.

1994 • 67 citations

Converting-enzyme inhibition and coronary blood flow.

1987 • 54 citations

Remodeling of the rat aortic endothelial layer during experimental hypertension. Changes in replication rate, cell density, and surface morphology.

1983 • 46 citations

Coronary Vasodilation Induced by Angiotensin-Converting Enzyme Inhibition In Vivo

1996 • 44 citations

Effects of antihypertensive agents on endothelium‐dependent and endothelium‐independent relaxations.

1989 • 42 citations

Captopril Attenuates Adrenergic Vasoconstriction in Rat Mesenteric Arteries by Angiotensin-Dependent and -Independent Mechanisms

1981 • 38 citations

Effect of angiotensin converting enzyme inhibition on cardiovascular regulation during reflex sympathetic activation in sodium-replete patients with essential hypertension

1989 • 31 citations

Effects of Sympathetic Nerve Stimulation are Attenuated by the Converting Enzyme Inhibitor Hoe 498 in Isolated Rabbit Hearts

1984 • 27 citations

Effects of Teprotide, Captopril and Enalaprilat on Arterial Wall Kininase and Angiotensin Converting Activity

1987 • 22 citations