Comparison of the Free Radical-scavenging Ability of Captopril and Ascorbic Acid in an In-vitro Model of Lipid Oxidation. Implications for Reperfusion Injury and ACE Inhibitor Therapy

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury.

1989 • 580 citations

Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues.

1989 • 518 citations

Studies on scavengers of active oxygen species. 1. Synthesis and biological activity of 2-O-alkylascorbic acids

1988 • 246 citations

Comparison of the efficiencies of several natural and synthetic antioxidants in aqueous SDS [sodium dodecyl sulfate] micelle solutions

1988 • 241 citations

Does captopril attenuate reperfusion-induced myocardial dysfunction by scavenging free radicals?

1988 • 229 citations

Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor

1989 • 156 citations

Protective effects of sulfhydryl-containing angiotensin converting enzyme inhibitors against free radical injury in endothelial cells

1990 • 113 citations

The autoxidation of unsaturated lipids in micelles. Synergism of inhibitors vitamins C and E

1983 • 106 citations

Benzophenone-photosensitized autoxidation of linoleate in solution and sodium dodecyl sulfate micelles

1987 • 80 citations

3-O-Alkylascorbic acids as free-radical quenchers: synthesis and inhibitory effect on lipid peroxidation

1991 • 79 citations

Captopril and enalaprilat do not scavenge the superoxide anion

1990 • 59 citations

Captopril and ramiprilat protect against free radical injury in isolated working rat hearts

1989 • 54 citations

Simple method for quantifying the distribution of organic substrates between the micellar and aqueous phases of sodium dodecyl sulfate solution

1984 • 49 citations

Free radical scavenging: a potentially beneficial action of thiol-containing angiotensin converting enzyme inhibitors

1990 • 36 citations

Sulfhydryl Group in Angiotensin Converting Enzyme Inhibitors and Superoxide Radical Formation

1990 • 20 citations

3-O-Alkylascorbic Acids as Free Radical Quenchers. II. Inhibitory Effects on Some Lipid Peroxidation Models.

1991 • 17 citations

Enhanced prostaglandin production in the ischemic-reperfused myocardium by captopril linked with its free radical scavenging action

1989 • 17 citations